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PDB: 127 件

8CL1
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HIV-1 mature capsid hexamer from CA-IP6 CLPs, bound to CPSF6 peptide.
分子名称: Cleavage and polyadenylation specificity factor subunit 6, Gag polyprotein
著者Stacey, J.C.V, Briggs, J.A.G.
登録日2023-02-16
公開日2023-04-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
6ECN
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BU of 6ecn by Molmil
HIV-1 CA 1/2-hexamer-EE
分子名称: HIV-1 CA
著者Summers, B.J, Xiong, Y.
登録日2018-08-08
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms.
Cell Host Microbe, 26, 2019
6EC2
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BU of 6ec2 by Molmil
Structure of HIV-1 CA 1/3-hexamer
分子名称: ACETATE ION, Capsid protein p24
著者Summers, B.J, Xiong, Y.
登録日2018-08-07
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms.
Cell Host Microbe, 26, 2019
7URN
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BU of 7urn by Molmil
Structure of HIV-1 capsid declination
分子名称: HIV-1 capsid protein, INOSITOL HEXAKISPHOSPHATE
著者Pornillos, O, Ganser-Pornillos, B.K, Schirra, R.T.
登録日2022-04-22
公開日2023-02-15
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献A molecular switch modulates assembly and host factor binding of the HIV-1 capsid.
Nat.Struct.Mol.Biol., 30, 2023
8CL2
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BU of 8cl2 by Molmil
HIV-1 mature capsid pentamer from CA-IP6 CLPs bound to CPSF6 peptide
分子名称: Gag polyprotein
著者Stacey, J.C.V, Briggs, J.A.G.
登録日2023-02-16
公開日2023-04-26
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
7N9V
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BU of 7n9v by Molmil
CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
分子名称: Capsid protein, Nanobody-GYAR
著者Tripler, T.N.
登録日2021-06-18
公開日2022-06-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献CA-targeting nanobody is a tool for studying HIV-1 capsid lattice interactions
To Be Published
8G6N
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BU of 8g6n by Molmil
HIV-1 capsid lattice bound to dNTPs
分子名称: Capsid protein
著者Highland, C.M, Dick, R.A.
登録日2023-02-15
公開日2023-05-03
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G6K
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BU of 8g6k by Molmil
HIV-1 CA lattice bound to IP6; from capsid-like particles
分子名称: Capsid protein
著者Highland, C.M, Dick, R.A.
登録日2023-02-15
公開日2023-05-03
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM.
Proc.Natl.Acad.Sci.USA, 120, 2023
8EJL
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BU of 8ejl by Molmil
Structure of HIV-1 capsid declination in complex with CPSF6-FG peptide
分子名称: Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein
著者Pornillos, O, Ganser-Pornillos, B.K, Schirra, R.T, dos Santos, N.F.B.
登録日2022-09-17
公開日2023-02-15
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献A molecular switch modulates assembly and host factor binding of the HIV-1 capsid.
Nat.Struct.Mol.Biol., 30, 2023
5L93
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BU of 5l93 by Molmil
An atomic model of HIV-1 CA-SP1 reveals structures regulating assembly and maturation
分子名称: Capsid protein p24
著者Schur, F.K.M, Obr, M, Hagen, W.J.H, Wan, W, Arjen, J.J, Kirkpatrick, J.M, Sachse, C, Kraeusslich, H.-G, Briggs, J.A.G.
登録日2016-06-09
公開日2016-07-13
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation.
Science, 353, 2016
6ECO
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BU of 6eco by Molmil
Hexamer-2-Foldon HIV-1 capsid platform
分子名称: HIV-1 capsid platform protein
著者Summers, B.J, Xiong, Y.
登録日2018-08-08
公開日2019-09-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Modular HIV-1 Capsid Assemblies Reveal Diverse Host-Capsid Recognition Mechanisms.
Cell Host Microbe, 26, 2019
5UPW
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BU of 5upw by Molmil
CryoEM Structure Refinement by Integrating NMR Chemical Shifts with Molecular Dynamics Simulations
分子名称: Gag polyprotein
著者Perilla, J.R.
登録日2017-02-04
公開日2017-03-01
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献CryoEM Structure Refinement by Integrating NMR Chemical Shifts with Molecular Dynamics Simulations.
J Phys Chem B, 121, 2017
6VWS
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BU of 6vws by Molmil
Hexamer of Helical HIV capsid by RASTR method
分子名称: HIV capsid protein
著者Zhao, H, Iqbal, N, Asturias, F, Kvaratskhelia, M, Vanblerkom, P.
登録日2020-02-20
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.08 Å)
主引用文献Structural and mechanistic bases for a potent HIV-1 capsid inhibitor.
Science, 370, 2020
7OVR
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BU of 7ovr by Molmil
Mature HIV-1 matrix structure
分子名称: HIV-1 matrix, MYRISTIC ACID, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Qu, K, Ke, Z.L, Zila, V, Anders-Oesswein, M, Glass, B, Muecksch, F, Mueller, R, Schultz, C, Mueller, B, Kraeusslich, H.G, Briggs, J.A.G.
登録日2021-06-15
公開日2021-08-18
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Maturation of the matrix and viral membrane of HIV-1.
Science, 373, 2021
3GV2
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BU of 3gv2 by Molmil
X-ray Structure of Hexameric HIV-1 CA
分子名称: Capsid protein p24,Carbon dioxide-concentrating mechanism protein CcmK homolog 4
著者Kelly, B.N.
登録日2009-03-30
公開日2009-06-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (7 Å)
主引用文献X-ray structures of the hexameric building block of the HIV capsid.
Cell(Cambridge,Mass.), 137, 2009
7OVQ
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BU of 7ovq by Molmil
Immature HIV-1 matrix structure
分子名称: Gag polyprotein, MYRISTIC ACID
著者Qu, K, Ke, Z.L, Zila, V, Anders-Oesswein, M, Glass, B, Muecksch, F, Mueller, R, Schultz, C, Mueller, B, Kraeusslich, H.G, Briggs, J.A.G.
登録日2021-06-15
公開日2021-08-18
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Maturation of the matrix and viral membrane of HIV-1.
Science, 373, 2021
1GWP
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BU of 1gwp by Molmil
STRUCTURE OF THE N-TERMINAL DOMAIN OF THE MATURE HIV-1 CAPSID PROTEIN
分子名称: GAG POLYPROTEIN
著者Tang, C, Gitti, R.K, Lee, B.M, Walker, J, Summers, M.F, Yoo, S, Sundquist, W.I.
登録日2002-03-22
公開日2002-06-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the N-Terminal 283-Residue Fragment of the Immature HIV-1 Gag Polyprotein
Nat.Struct.Biol., 9, 2002
6WAP
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BU of 6wap by Molmil
Atomic-Resolution Structure of HIV-1 Capsid Tubes by Magic Angle Spinning NMR
分子名称: HIV-1 capsid protein
著者Lu, M, Russell, R.W, Bryer, A, Quinn, C.M, Hou, G, Zhang, H, Schwieters, C.D, Perilla, J.R, Gronenborn, A.M, Polenova, T.
登録日2020-03-25
公開日2020-09-02
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR.
Nat.Struct.Mol.Biol., 27, 2020
2C55
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BU of 2c55 by Molmil
Solution Structure of the Human Immunodeficiency Virus Type 1 p6 Protein
分子名称: PROTEIN P6
著者Fossen, T, Wray, V, Bruns, K, Rachmat, J, Henklein, P, Tessmer, U, Maczurek, A, Klinger, P, Schubert, U.
登録日2005-10-25
公開日2005-11-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure of the Human Immunodeficiency Virus Type 1 P6 Protein.
J.Biol.Chem., 280, 2005
7P3O
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BU of 7p3o by Molmil
Solution structures of HIV-1 and SIVmac p6 and their interaction with accessory proteins Vpr and Vpx in the presence of DPC micelles
分子名称: Gag protein
著者Wang, X, Nonin-Lecomte, S, Bouaziz, S.
登録日2021-07-08
公開日2023-01-18
最終更新日2024-03-27
実験手法SOLUTION NMR
主引用文献Solution structures of HIV-1 and SIVmac p6 and their interaction with accessory proteins Vpr and Vpx in the presence of DPC micelles
To Be Published
6X63
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BU of 6x63 by Molmil
Atomic-Resolution Structure of HIV-1 Capsid Tubes by Magic Angle Spinning NMR
分子名称: HIV-1 capsid protein
著者Lu, M, Russell, R.W, Bryer, A, Quinn, C.M, Hou, G, Zhang, H, Schwieters, C.D, Perilla, J.R, Gronenborn, A.M, Polenova, T.
登録日2020-05-27
公開日2020-09-02
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR.
Nat.Struct.Mol.Biol., 27, 2020
7R7P
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BU of 7r7p by Molmil
Immature HIV-1 CACTD-SP1 lattice with Bevirimat (BVM) and Inositol hexakisphosphate (IP6)
分子名称: 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid, Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
著者Sarkar, S, Zadrozny, K.K, Zadorozhnyi, R, Russell, R.W, Quinn, C.M, Kleinpeter, A, Ablan, S, Meshkin, H, Perilla, J.R, Ganser-Pornillos, B.K, Pornillos, O, Freed, E.O, Gronenborn, A.M, Polenova, T.
登録日2021-06-25
公開日2023-02-15
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Structural basis of HIV-1 maturation inhibitor binding and activity.
Nat Commun, 14, 2023
7R7Q
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BU of 7r7q by Molmil
Immature HIV-1 CACTD-SP1 lattice with Inositol hexakisphosphate (IP6)
分子名称: Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
著者Sarkar, S, Zadrozny, K.K, Zadorozhnyi, R, Russell, R.W, Quinn, C.M, Kleinpeter, A, Ablan, S, Meshkin, H, Perilla, J.R, Ganser-Pornillos, B.K, Pornillos, O, Freed, E.O, Gronenborn, A.M, Polenova, T.
登録日2021-06-25
公開日2023-02-15
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Structural basis of HIV-1 maturation inhibitor binding and activity.
Nat Commun, 14, 2023
6RWG
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BU of 6rwg by Molmil
Structure of HIV-1 CAcSP1NC mutant(W41A,M42A) interacting with maturation inhibitor EP39
分子名称: Gag polyprotein, ZINC ION
著者Chen, X, Coric, P, Larue, V, Nonin-Lecomte, S, Bouaziz, S, Structural Genomics Consortium (SGC)
登録日2019-06-05
公開日2020-05-20
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献The HIV-1 maturation inhibitor, EP39, interferes with the dynamic helix-coil equilibrium of the CA-SP1 junction of Gag.
Eur.J.Med.Chem., 204, 2020
5IRT
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BU of 5irt by Molmil
Dimerization interface of the noncrystalline HIV-1 capsid protein lattice from solid state NMR spectroscopy of tubular assemblies
分子名称: Capsid protein p24
著者Bayro, M.J, Tycko, R.
登録日2016-03-14
公開日2016-06-22
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Structure of the Dimerization Interface in the Mature HIV-1 Capsid Protein Lattice from Solid State NMR of Tubular Assemblies.
J.Am.Chem.Soc., 138, 2016

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件を2024-08-07に公開中

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