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PDB: 127 件
6AXT
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BU of 6axt by Molmil
Structure of the T58S/T107I/P122A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Identification of a novel element in HIV-1 capsid critical for assembly and maturation
To be published
6AXW
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BU of 6axw by Molmil
Structure of the I124A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation.
MBio, 9, 2018
7E1K
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BU of 7e1k by Molmil
Crystal structure of Pr55Gag-matrix domain in complex with IP6 in space group R32
分子名称: Capsid protein p24, INOSITOL HEXAKISPHOSPHATE
著者DeMirci, H, Senda, T, Destan, E.
登録日2021-02-01
公開日2021-08-04
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of Pr55Gag-matrix domain in complex with IP6 in space group R32
To Be Published
6AXS
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BU of 6axs by Molmil
Structure of the V11I/T58A/P122A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Identification of a novel element in HIV-1 capsid critical for assembly and maturation
To be published
6B2G
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BU of 6b2g by Molmil
P38A mutant of HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-20
公開日2018-09-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.407 Å)
主引用文献Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.
Nat Commun, 14, 2023
4XFX
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BU of 4xfx by Molmil
Structure of the native full-length HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2014-12-29
公開日2015-06-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability.
Science, 349, 2015
7RHN
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BU of 7rhn by Molmil
Co-crystal structure of Q67H mutant of disulfide stabilized HIV-1 CA hexamer and lenacapavir
分子名称: CHLORIDE ION, Capsid protein p24, IODIDE ION, ...
著者Bester, S.M, Kvaratskhelia, M.
登録日2021-07-17
公開日2022-07-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structural and Mechanistic Bases of Viral Resistance to HIV-1 Capsid Inhibitor Lenacapavir.
Mbio, 13, 2022
6B2I
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BU of 6b2i by Molmil
E45A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-20
公開日2018-09-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.
Nat Commun, 14, 2023
6AY9
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BU of 6ay9 by Molmil
Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide
分子名称: CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein, ...
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.
Nat Commun, 14, 2023
5TSV
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BU of 5tsv by Molmil
HIV-1 CA hexamer with NUP153 peptide - R3 crystal form
分子名称: 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, HIV-1 CA protein, Nuclear pore complex protein Nup153
著者Skorupka, K, Ganser-Pornillos, B.K, Pornillos, O.
登録日2016-10-31
公開日2017-11-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献HIV-1 CA hexamer with NUP153 peptide - R3 crystal form
To Be Published
8CKY
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BU of 8cky by Molmil
HIV-1 mature capsid hexamer from CA-IP6 CLPs, bound to Nup153 peptide
分子名称: Gag polyprotein, Nuclear pore complex protein Nup153
著者Stacey, J.C.V, Briggs, J.A.G.
登録日2023-02-16
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding.
Proc.Natl.Acad.Sci.USA, 120, 2023
4WYM
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BU of 4wym by Molmil
Structural basis of HIV-1 capsid recognition by CPSF6
分子名称: Capsid protein p24, ISOFORM 2 OF CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6
著者Battacharya, A, Taylor, A.B, Hart, P.J, Ivanov, D.N.
登録日2014-11-17
公開日2014-12-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.
Proc.Natl.Acad.Sci.USA, 111, 2014
6AXX
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BU of 6axx by Molmil
Structure of the T58A/I124A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification of a novel element in HIV-1 capsid critical for assembly and maturation
To be published
6B2H
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BU of 6b2h by Molmil
P38A/T216I mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-20
公開日2018-09-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization.
Nat Commun, 14, 2023
7MKC
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BU of 7mkc by Molmil
N74D mutant of the HIV-1 capsid protein in complex with PF-3450074 (PF74)
分子名称: IODIDE ION, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE, capsid protein
著者Kirby, K.A, Sarafianos, S.G.
登録日2021-04-23
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献TRIM5alpha Restriction of HIV-1-N74D Viruses in Lymphocytes Is Caused by a Loss of Cyclophilin A Protection.
Viruses, 14, 2022
6BHT
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BU of 6bht by Molmil
HIV-1 CA hexamer in complex with IP6, orthorhombic crystal form
分子名称: Capsid protein p24, INOSITOL HEXAKISPHOSPHATE
著者Zadrozny, K, Wagner, J.M, Ganser-Pornillos, B.K, Pornillos, O.
登録日2017-10-31
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.689 Å)
主引用文献Inositol phosphates are assembly co-factors for HIV-1.
Nature, 560, 2018
7M9F
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BU of 7m9f by Molmil
Structure of the wild-type native full-length HIV-1 capsid protein in complex with ZW-1261
分子名称: HIV-1 capsid protein, IODIDE ION, N-(4-chlorophenyl)-Nalpha-[(5-hydroxy-1H-indol-3-yl)acetyl]-N-methyl-L-phenylalaninamide
著者Kirby, K.A, Sarafianos, S.G.
登録日2021-03-31
公開日2022-04-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular Dynamics Free Energy Simulations Reveal the Mechanism for the Antiviral Resistance of the M66I HIV-1 Capsid Mutation.
Viruses, 13, 2021
4XFZ
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BU of 4xfz by Molmil
Structure of the native full-length HIV-1 capsid protein in complex with PF-3450074 (PF74)
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION, ...
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2014-12-29
公開日2015-06-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability.
Science, 349, 2015
8QV4
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BU of 8qv4 by Molmil
Hexameric HIV-1 CA in complex with DDD01728503
分子名称: 1,2-ETHANEDIOL, Spacer peptide 1, ethyl 2-(3-oxidanylidene-2,4-dihydroquinoxalin-1-yl)ethanoate
著者Petit, A.P, Fyfe, P.K.
登録日2023-10-17
公開日2024-03-27
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Application of an NMR/Crystallography Fragment Screening Platform for the Assessment and Rapid Discovery of New HIV-CA Binding Fragments.
Chemmedchem, 19, 2024
7E1J
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BU of 7e1j by Molmil
Crystal structure of Pr55Gag-matrix domain in complex with IP6 in space group C121
分子名称: Capsid protein p24, INOSITOL HEXAKISPHOSPHATE
著者DeMirci, H, Senda, T, Destan, E.
登録日2021-02-01
公開日2021-08-04
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Crystal structure of Pr55Gag-matrix domain in complex with IP6 in space group C121
to be published
6R6Q
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BU of 6r6q by Molmil
HIV capsid hexamer with IP5 ligand
分子名称: Gag polyprotein
著者James, L.C.
登録日2019-03-27
公開日2020-05-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献HIV hexamer
to be published
5O2U
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BU of 5o2u by Molmil
Llama VHH in complex with p24
分子名称: Capsid protein p24, VHH 59H10
著者Caillat, C, Verrips, T, Weissenhorn, W.
登録日2017-05-22
公開日2017-06-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Unravelling the Molecular Basis of High Affinity Nanobodies against HIV p24: In Vitro Functional, Structural, and in Silico Insights.
ACS Infect Dis, 3, 2017
6AXV
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BU of 6axv by Molmil
Structure of the T58S/T107I/P122A mutant of the HIV-1 capsid protein in complex with PF-3450074 (PF74)
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION, ...
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Identification of a novel element in HIV-1 capsid critical for assembly and maturation
To be published
6AXY
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BU of 6axy by Molmil
Structure of the V11I/T58A/I124A mutant of the HIV-1 capsid protein
分子名称: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
著者Gres, A.T, Kirby, K.A, Sarafianos, S.G.
登録日2017-09-07
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Identification of a novel element in HIV-1 capsid critical for assembly and maturation
To be published
4U0B
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BU of 4u0b by Molmil
Hexamer HIV-1 CA in complex with CPSF6 peptide, P212121 crystal form
分子名称: Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6
著者Price, A.J, Jacques, D.A, James, L.C.
登録日2014-07-11
公開日2014-11-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Plos Pathog., 10, 2014

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件を2024-07-10に公開中

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