4U0B

Hexamer HIV-1 CA in complex with CPSF6 peptide, P212121 crystal form

Summary for 4U0B

Entry DOI	10.2210/pdb4u0b/pdb
Related	4U0A
Descriptor	Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6 (2 entities in total)
Functional Keywords	capsid, complex, viral protein
Biological source	Human immunodeficiency virus type 1 group M subtype B (HIV-1) More
Cellular location	Matrix protein p17: Virion . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion : P12493 Nucleus : Q16630
Total number of polymer chains	24
Total formula weight	324144.80
Authors	Price, A.J.,Jacques, D.A.,James, L.C. (deposition date: 2014-07-11, release date: 2014-11-12, Last modification date: 2023-12-20)
Primary citation	Price, A.J.,Jacques, D.A.,McEwan, W.A.,Fletcher, A.J.,Essig, S.,Chin, J.W.,Halambage, U.D.,Aiken, C.,James, L.C. Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly. Plos Pathog., 10:e1004459-e1004459, 2014 Cited by PubMed: 25356722 DOI: 10.1371/journal.ppat.1004459 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation