2FZS
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1YG6
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![BU of 1yg6 by Molmil](/molmil-images/mine/1yg6) | ClpP | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ATP-dependent Clp protease proteolytic subunit | 著者 | Bewley, M.C, Graziano, V, Griffin, K, Flanagan, J.M. | 登録日 | 2005-01-04 | 公開日 | 2006-04-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The asymmetry in the mature amino-terminus of ClpP facilitates a local symmetry match in ClpAP and ClpXP complexes. J.Struct.Biol., 153, 2006
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6NB1
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![BU of 6nb1 by Molmil](/molmil-images/mine/6nb1) | Crystal structure of Escherichia coli ClpP protease complexed with small molecule activator, ACP1-06 | 分子名称: | ATP-dependent Clp protease proteolytic subunit, GLYCEROL, N-{2-[(2-chlorophenyl)sulfanyl]ethyl}-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]sulfonyl}propanamide | 著者 | Mabanglo, M.F, Houry, W.A, Eger, B.T, Bryson, S, Pai, E.F. | 登録日 | 2018-12-06 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores. Commun Biol, 2, 2019
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3MT6
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![BU of 3mt6 by Molmil](/molmil-images/mine/3mt6) | Structure of ClpP from Escherichia coli in complex with ADEP1 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACYLDEPSIPEPTIDE 1, ATP-dependent Clp protease proteolytic subunit | 著者 | Chung, Y.S. | 登録日 | 2010-04-30 | 公開日 | 2010-11-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP. Chem.Biol., 17, 2010
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1TYF
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![BU of 1tyf by Molmil](/molmil-images/mine/1tyf) | |
8E91
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1YG8
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![BU of 1yg8 by Molmil](/molmil-images/mine/1yg8) | |
6W1Z
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![BU of 6w1z by Molmil](/molmil-images/mine/6w1z) | ClpAP Engaged1 State bound to RepA-GFP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | 著者 | Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. | 登録日 | 2020-03-04 | 公開日 | 2020-05-06 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
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6WR2
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7MK5
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![BU of 7mk5 by Molmil](/molmil-images/mine/7mk5) | Crystal structure of Escherichia coli ClpP covalently inhibited by clipibicyclene | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-[(1E)-3-{[(2E,4E,6E,8S)-8-hydroxy-4-methyldeca-2,4,6-trienoyl]amino}-3-oxoprop-1-en-1-yl]azete-1(2H)-carboxylic acid, ACETATE ION, ... | 著者 | Culp, E.J, Sychantha, D, Hobson, C, Pawlowski, A.J, Prehna, G, Wright, G.D. | 登録日 | 2021-04-21 | 公開日 | 2022-02-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | ClpP inhibitors are produced by a widespread family of bacterial gene clusters. Nat Microbiol, 7, 2022
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6UQE
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![BU of 6uqe by Molmil](/molmil-images/mine/6uqe) | ClpA/ClpP Disengaged State bound to RepA-GFP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease proteolytic subunit, ... | 著者 | Lopez, K.L, Rizo, A.R, Southworth, D.R. | 登録日 | 2019-10-18 | 公開日 | 2020-04-22 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
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6W20
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![BU of 6w20 by Molmil](/molmil-images/mine/6w20) | ClpAP Disengaged State bound to RepA-GFP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | 著者 | Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. | 登録日 | 2020-03-04 | 公開日 | 2020-05-06 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
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8E7V
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![BU of 8e7v by Molmil](/molmil-images/mine/8e7v) | Cryo-EM structure of substrate-free DNClpX.ClpP from singly capped particles | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ... | 著者 | Ghanbarpour, A, Cohen, S, Davis, J.H, Sauer, R.T. | 登録日 | 2022-08-24 | 公開日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structure of substrate-free DNClpX.ClpP Nat Commun, 2023
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6UQO
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![BU of 6uqo by Molmil](/molmil-images/mine/6uqo) | ClpA/ClpP Engaged State bound to RepA-GFP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp endopeptidase proteolytic subunit ClpP, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | 著者 | Lopez, K.L, Rizo, A.N, Southworth, D.R. | 登録日 | 2019-10-21 | 公開日 | 2020-04-22 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
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8E8Q
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![BU of 8e8q by Molmil](/molmil-images/mine/8e8q) | Cryo-EM structure of substrate-free DNClpX.ClpP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ... | 著者 | Ghanbarpour, A, Cohen, S, Davis, J.H, Sauer, R.T. | 登録日 | 2022-08-25 | 公開日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Cryo-EM structure of substrate-free DNClpX.ClpP Nat Commun, 2023
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6WRF
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![BU of 6wrf by Molmil](/molmil-images/mine/6wrf) | ClpX-ClpP complex bound to GFP-ssrA, recognition complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | 著者 | Fei, X, Sauer, R.T. | 登録日 | 2020-04-29 | 公開日 | 2020-11-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates. Elife, 9, 2020
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6WSG
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![BU of 6wsg by Molmil](/molmil-images/mine/6wsg) | |
6PPE
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![BU of 6ppe by Molmil](/molmil-images/mine/6ppe) | ClpP and ClpX IGF loop in ClpX-ClpP complex with D7 symmetry | 分子名称: | ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit | 著者 | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | 登録日 | 2019-07-06 | 公開日 | 2020-03-11 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife, 9, 2020
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3HLN
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![BU of 3hln by Molmil](/molmil-images/mine/3hln) | Crystal structure of ClpP A153C mutant with inter-heptamer disulfide bonds | 分子名称: | ATP-dependent Clp protease proteolytic subunit, CALCIUM ION | 著者 | Kimber, M.S, Yu, A.Y.H, Borg, M, Chan, H.S, Houry, W.A. | 登録日 | 2009-05-27 | 公開日 | 2010-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural and Theoretical Studies Indicate that the Cylindrical Protease ClpP Samples Extended and Compact Conformations. Structure, 18, 2010
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7UIY
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![BU of 7uiy by Molmil](/molmil-images/mine/7uiy) | ClpAP complex bound to ClpS N-terminal extension, class IIIa | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | 著者 | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | 登録日 | 2022-03-29 | 公開日 | 2022-10-26 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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7UIZ
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![BU of 7uiz by Molmil](/molmil-images/mine/7uiz) | ClpAP complex bound to ClpS N-terminal extension, class IIc | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | 著者 | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | 登録日 | 2022-03-29 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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7UIX
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![BU of 7uix by Molmil](/molmil-images/mine/7uix) | ClpAP complex bound to ClpS N-terminal extension, class I | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | 著者 | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | 登録日 | 2022-03-29 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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7UJ0
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![BU of 7uj0 by Molmil](/molmil-images/mine/7uj0) | ClpAP complex bound to ClpS N-terminal extension, class IIIb | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | 著者 | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | 登録日 | 2022-03-29 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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6W21
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![BU of 6w21 by Molmil](/molmil-images/mine/6w21) | ClpAP Engaged2 State bound to RepA-GFP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ... | 著者 | Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R. | 登録日 | 2020-03-04 | 公開日 | 2020-05-13 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nat.Struct.Mol.Biol., 27, 2020
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7UIW
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![BU of 7uiw by Molmil](/molmil-images/mine/7uiw) | ClpAP complex bound to ClpS N-terminal extension, class IIb | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease adapter protein ClpS, ... | 著者 | Kim, S, Fei, X, Sauer, R.T, Baker, T.A. | 登録日 | 2022-03-29 | 公開日 | 2022-11-09 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | AAA+ protease-adaptor structures reveal altered conformations and ring specialization. Nat.Struct.Mol.Biol., 29, 2022
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