7OF0
 
 | | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with MTERF4-NSUN4 (dataset1). | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R. | | 登録日 | 2021-05-04 | | 公開日 | 2021-06-09 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Nat Commun, 12, 2021
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7QI4
 | | Human mitochondrial ribosome at 2.2 A resolution (bound to partly built tRNAs and mRNA) | | 分子名称: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | | 著者 | Singh, V, Itoh, Y, Amunts, A. | | 登録日 | 2021-12-14 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.21 Å) | | 主引用文献 | Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications.
Biorxiv, 2023
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8QU5
 | | mt-LSU assembly intermediate in GTPBP8 knock-out cells, state 2 | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Valentin Gese, G, Cipullo, M, Rorbach, J, Hallberg, B.M. | | 登録日 | 2023-10-13 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.42 Å) | | 主引用文献 | GTPBP8 plays a role in mitoribosome formation in human mitochondria
Nat Commun, 2024
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7OF7
 | | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with MTERF4-NSUN4 and GTPBP5 (dataset1). | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R. | | 登録日 | 2021-05-04 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Nat Commun, 12, 2021
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7O9M
 | | Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1 and the MALSU module | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Valentin Gese, G, Hallberg, B.M. | | 登録日 | 2021-04-16 | | 公開日 | 2021-06-30 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structural basis for late maturation steps of the human mitoribosomal large subunit.
Nat Commun, 12, 2021
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7PO4
 | | Assembly intermediate of human mitochondrial ribosome large subunit (largely unfolded rRNA with MALSU1, L0R8F8 and ACP) | | 分子名称: | 16SrRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Itoh, Y, Khawaja, A, Rorbach, J, Amunts, A. | | 登録日 | 2021-09-08 | | 公開日 | 2022-06-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | | 主引用文献 | Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Nature, 606, 2022
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6ZM6
 | | Human mitochondrial ribosome in complex with mRNA, A/A tRNA and P/P tRNA | | 分子名称: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | | 著者 | Itoh, Y, Andrell, J, Amunts, A. | | 登録日 | 2020-07-01 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | | 主引用文献 | Mechanism of membrane-tethered mitochondrial protein synthesis.
Science, 371, 2021
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7OF6
 | | Structure of mature human mitochondrial ribosome large subunit in complex with GTPBP6 (PTC conformation 2). | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R. | | 登録日 | 2021-05-04 | | 公開日 | 2021-06-09 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Nat Commun, 12, 2021
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7QI5
 | | Human mitochondrial ribosome in complex with mRNA, A/A-, P/P- and E/E-tRNAs at 2.63 A resolution | | 分子名称: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | | 著者 | Singh, V, Itoh, Y, Amunts, A. | | 登録日 | 2021-12-14 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | | 主引用文献 | Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications.
Biorxiv, 2023
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7OF2
 | | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with GTPBP6. | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R. | | 登録日 | 2021-05-04 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Nat Commun, 12, 2021
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7OF4
 | | Structure of mature human mitochondrial ribosome large subunit in complex with GTPBP6 (PTC conformation 1). | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R. | | 登録日 | 2021-05-04 | | 公開日 | 2021-06-09 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Nat Commun, 12, 2021
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7OF3
 | | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with MTERF4-NSUN4 (dataset2). | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R. | | 登録日 | 2021-05-04 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Nat Commun, 12, 2021
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8ANY
 | | Human mitochondrial ribosome in complex with LRPPRC, SLIRP, A-site, P-site, E-site tRNAs and mRNA | | 分子名称: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | | 著者 | Singh, V, Itoh, Y, Amunts, A. | | 登録日 | 2022-08-06 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Structural basis of LRPPRC-SLIRP-dependent translation by the
mitoribosome
To Be Published
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6ZM5
 | | Human mitochondrial ribosome in complex with OXA1L, mRNA, A/A tRNA, P/P tRNA and nascent polypeptide | | 分子名称: | 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ... | | 著者 | Itoh, Y, Andrell, J, Amunts, A. | | 登録日 | 2020-07-01 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Mechanism of membrane-tethered mitochondrial protein synthesis.
Science, 371, 2021
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7QH7
 | | Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 4 | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Rebelo-Guiomar, P, Pellegrino, S, Dent, K.C, Warren, A.J, Minczuk, M. | | 登録日 | 2021-12-10 | | 公開日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit.
Nat Commun, 13, 2022
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8K2A
 | | Cryo-EM structure of the human 55S mitoribosome with Tigecycline | | 分子名称: | 12S rRNA, 16S rRNA, 39S ribosomal protein L22, ... | | 著者 | Li, X, Wang, M, Cheng, J. | | 登録日 | 2023-07-12 | | 公開日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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7OF5
 | | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with MTERF4-NSUN4 and GTPBP5 (dataset2). | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R. | | 登録日 | 2021-05-04 | | 公開日 | 2021-06-09 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling.
Nat Commun, 12, 2021
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7ODR
 | | State A of the human mitoribosomal large subunit assembly intermediate | | 分子名称: | 16S mitochondrial rRNA, DNA (31-MER),16S mitochondrial rRNA, 39S ribosomal protein L10, ... | | 著者 | Lenarcic, T, Jaskolowski, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Saurer, M, Lee, R.G, Rackham, O, Filipovska, A, Ban, N. | | 登録日 | 2021-04-30 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Nat Commun, 12, 2021
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8OIT
 | | 39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA | | 分子名称: | 16S rRNA, 39S ribosomal protein L1, mitochondrial, ... | | 著者 | Saurer, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Ban, N. | | 登録日 | 2023-03-23 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Science, 380, 2023
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6VMI
 | | Structure of the human mitochondrial ribosome-EF-G1 complex (ClassIII) | | 分子名称: | 12s rRNA, 16s rRNA, 28S ribosomal protein S10, ... | | 著者 | Sharma, M.R, Koripella, R.K, Agrawal, R.K. | | 登録日 | 2020-01-28 | | 公開日 | 2020-08-05 | | 最終更新日 | 2021-02-17 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation.
Nat Commun, 11, 2020
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6VLZ
 | | Structure of the human mitochondrial ribosome-EF-G1 complex (ClassI) | | 分子名称: | 12s rRNA, 16s rRNA, 28S ribosomal protein S10, ... | | 著者 | Sharma, M.R, Koripella, R.K, Agrawal, R.K. | | 登録日 | 2020-01-27 | | 公開日 | 2020-08-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation.
Nat Commun, 11, 2020
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7QI6
 | | Human mitochondrial ribosome in complex with mRNA, A/P- and P/E-tRNAs at 2.98 A resolution | | 分子名称: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | | 著者 | Singh, V, Itoh, Y, Amunts, A. | | 登録日 | 2021-12-14 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications.
Biorxiv, 2023
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8QSJ
 | | Human mitoribosomal large subunit assembly intermediate 2 with GTPBP7 | | 分子名称: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Ritter, C, Nguyen, T.G, Kummer, E. | | 登録日 | 2023-10-10 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome.
Nat Commun, 14, 2023
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5OOM
 | | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA | | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V. | | 登録日 | 2017-08-08 | | 公開日 | 2017-09-13 | | 最終更新日 | 2023-03-15 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
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8PK0
 | | human mitoribosomal large subunit assembly intermediate 1 with GTPBP10-GTPBP7 | | 分子名称: | 16S rRNA + pre-H68-71 segment, 39S ribosomal protein L10, mitochondrial, ... | | 著者 | Kummer, E, Nguyen, T.G, Ritter, C. | | 登録日 | 2023-06-23 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome.
Nat Commun, 14, 2023
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