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PDB: 18 件
3TJQ
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BU of 3tjq by Molmil
N-domain of HtrA1
分子名称: CHLORIDE ION, GLYCEROL, PLATINUM (II) ION, ...
著者Eigenbrot, C, Ultsch, M.
登録日2011-08-24
公開日2012-05-16
最終更新日2012-06-27
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural and Functional Analysis of HtrA1 and Its Subdomains.
Structure, 20, 2012
7SJP
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BU of 7sjp by Molmil
anti-HtrA1 Fab15H6.v4 bound to HtrA1-LoopA peptide
分子名称: GLYCEROL, Heavy Chain, HtrA1-LoopA peptide, ...
著者Ultsch, M.H, Gerhardy, S.
登録日2021-10-18
公開日2022-09-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration.
Nat Commun, 13, 2022
6Z0Y
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BU of 6z0y by Molmil
HtrA1 inactive protease domain S328A with CARASIL mutations D174R R274Q
分子名称: SULFATE ION, Serine protease HTRA1
著者Vetter, I.R, Stege, P, Ingendahl, L, Ehrmann, M.
登録日2020-05-11
公開日2021-05-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Repair strategies addressing pathogenic protein conformations
To Be Published
3TJO
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BU of 3tjo by Molmil
HtrA1 catalytic domain, mutationally inactivated
分子名称: GLYCEROL, SULFATE ION, Serine protease HTRA1, ...
著者Eigenbrot, C, Ultsch, M.
登録日2011-08-24
公開日2012-05-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structural and Functional Analysis of HtrA1 and Its Subdomains.
Structure, 20, 2012
6Z0E
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BU of 6z0e by Molmil
HtrA1 inactive protease domain S328A with CARASIL mutation R274Q
分子名称: CALCIUM ION, Serine protease HTRA1
著者Vetter, I.R, Stege, P, Ingendahl, L, Ehrmann, M.
登録日2020-05-08
公開日2021-05-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Repair strategies addressing pathogenic protein conformations
To Be Published
3NUM
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BU of 3num by Molmil
Substrate induced remodeling of the active site regulates HtrA1 activity
分子名称: Serine protease HTRA1
著者Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M.
登録日2010-07-07
公開日2011-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
3NZI
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BU of 3nzi by Molmil
Substrate induced remodeling of the active site regulates HtrA1 activity
分子名称: Citrate synthase, Serine protease HTRA1
著者Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M.
登録日2010-07-16
公開日2011-02-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
8SDP
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BU of 8sdp by Molmil
HTRA-1 PDSA bound to CKP 3A7
分子名称: Cysteine knot peptide 3A7, SULFATE ION, Serine protease HTRA1
著者Ultsch, M.H, Kirchhofer, D, Wei, Y.
登録日2023-04-07
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献HTRA-1 PDSA bound to CKP 3A7
To Be Published
8SE7
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BU of 8se7 by Molmil
HTRA-1 PDSA bound to CKP 1A8
分子名称: Cysteine knot peptide, Serine protease HTRA1
著者Ultsch, M.H, Kirchhofer, D, Wei, Y.
登録日2023-04-08
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献HTRA-1 PDSA bound to CKP 1A8
To Be Published
3TJN
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BU of 3tjn by Molmil
HtrA1 catalytic domain, apo form
分子名称: Serine protease HTRA1
著者Eigenbrot, C, Ultsch, M.
登録日2011-08-24
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and Functional Analysis of HtrA1 and Its Subdomains.
Structure, 20, 2012
8SDM
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BU of 8sdm by Molmil
HTRA-1 PDSA bound to CKP 3B3
分子名称: Cysteine-containing peptide 3B3, Serine protease HTRA1
著者Ultsch, M.H, Kirchhofer, D, Wei, Y.
登録日2023-04-07
公開日2024-07-03
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献HTRA-1 PDSA bound to CKP 3B3
To Be Published
6Z0X
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BU of 6z0x by Molmil
HtrA1 inactive protease domain S328A with CARASIL mutations D174R R274Q
分子名称: SULFATE ION, Serine protease HTRA1
著者Vetter, I.R, Stege, P, Ingendahl, L, Ehrmann, M.
登録日2020-05-11
公開日2021-05-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Repair strategies addressing pathogenic protein conformations
To Be Published
8SE8
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BU of 8se8 by Molmil
HTRA-1 PD/SA bound to CKP 1G10
分子名称: Cysteine knot peptide, GLYCEROL, SULFATE ION, ...
著者Ultsch, M.H.
登録日2023-04-08
公開日2024-07-03
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献HTRA-1 PD/SA bound to CKP 1G10
To Be Published
3NWU
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BU of 3nwu by Molmil
Substrate induced remodeling of the active site regulates HtrA1 activity
分子名称: SULFATE ION, Serine protease HTRA1
著者Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M.
登録日2010-07-11
公開日2011-02-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
7SJO
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BU of 7sjo by Molmil
HtrA1S328A:Fab15H6.v4 complex
分子名称: Fab15H6.v4 Heavy Chain, Fab15H6.v4 Light Chain, Serine protease HTRA1
著者Gerhardy, S, Green, E, Estevez, A, Arthur, C.P, Ultsch, M, Rohou, A, Kirchhofer, D.
登録日2021-10-18
公開日2022-09-07
最終更新日2022-09-21
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration.
Nat Commun, 13, 2022
7SJN
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BU of 7sjn by Molmil
HtrA1:Fab15H6.v4 complex
分子名称: Fab15H6.v4 Heavy Chain, Fab15H6.v4 Light Chain, Serine protease HTRA1
著者Gerhardy, S, Green, E, Estevez, A, Arthur, C.P, Ultsch, M, Rohou, A, Kirchhofer, D.
登録日2021-10-18
公開日2022-09-07
最終更新日2022-09-21
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Allosteric inhibition of HTRA1 activity by a conformational lock mechanism to treat age-related macular degeneration.
Nat Commun, 13, 2022
2YTW
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BU of 2ytw by Molmil
Solution structure of the PDZ-domain of human protease HTRA 1 precursor
分子名称: Serine protease HTRA1
著者Goroncy, A.K, Saito, K, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2008-04-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PDZ-domain of human protease HTRA 1 precursor
To be Published
2JOA
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BU of 2joa by Molmil
HtrA1 bound to an optimized peptide: NMR assignment of PDZ domain and ligand resonances
分子名称: Peptide H1-C1, Serine protease HTRA1
著者Runyon, S.T, Zhang, Y, Appleton, B.A, Sazinksy, S.L, Wu, P, Pan, B, Wiesmann, C, Skelton, N.J, Sidhu, S.S.
登録日2007-03-01
公開日2007-11-20
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3
Protein Sci., 16, 2007

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件を2024-07-10に公開中

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