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PDB: 322 件

2VAA
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MHC CLASS I H-2KB HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
分子名称: BETA-2 MICROGLOBULIN, MHC CLASS I H-2KB HEAVY CHAIN, VESICULAR STOMATITIS VIRUS NUCLEOPROTEIN
著者Fremont, D.H, Wilson, I.A.
登録日1994-11-01
公開日1996-06-20
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb.
Science, 257, 1992
3TBT
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CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH THE LCMV-DERIVED GP33 ALTERED PEPTIDE ligand (V3P, Y4S)
分子名称: Beta-2-microglobulin, GLYCOPROTEIN G1, H-2 class I histocompatibility antigen, ...
著者Duru, A.D, Allerbring, E.B, Uchtenhagen, H, Mazumdar, P.A, Badia-Martinez, D, Madhurantakam, C, Sandalova, T, Nygren, P, Achour, A.
登録日2011-08-08
公開日2012-08-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Conversion of a T cell viral antagonist into an agonist through higher stabilization and conserved molecular mimicry: Implications for TCR recognition
To be Published
3P4O
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Crystal Structure of H2-Kb in complex with the mutant NP205-LCMV-V3A epitope YTAKYPNL, an 8-mer modified peptide from the LCMV
分子名称: ACETYL GROUP, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Gras, S, Guillonneau, C, Rossjohn, J.
登録日2010-10-06
公開日2011-10-12
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of H2-Kb in complex with the mutant NP205-LCMV-V3A epitope YTAKYPNL, an 8-mer modified peptide from the LCMV
To be Published
3CH1
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BU of 3ch1 by Molmil
Crystal structure of H-2Db in complex with chimeric gp100
分子名称: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
著者Badia-Martinez, D, Achour, A.
登録日2008-03-06
公開日2009-03-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.
Cancer Res., 69, 2009
8D5F
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BU of 8d5f by Molmil
The complex of Gtf2b neoantigen TGAARFDEF Presented by H2-Dd
分子名称: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
著者Custodio, J.M.F, Baker, B.M.
登録日2022-06-04
公開日2022-07-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural and physical features that distinguish tumor-controlling from inactive cancer neoepitopes.
Proc.Natl.Acad.Sci.USA, 120, 2023
4PV8
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Crystal Structure of H2Kb-Q600F complex
分子名称: ACETATE ION, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Twist, K.-A, Rossjohn, J, Gras, S.
登録日2014-03-15
公開日2014-04-23
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural and functional correlates of enhanced antiviral immunity generated by heteroclitic CD8 T cell epitopes.
J.Immunol., 192, 2014
3WS3
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BU of 3ws3 by Molmil
Crystal Structure of H-2D in complex with an insulin derived peptide
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
著者Kumar, P.R, Mukherjee, G, Samanta, D, DiLorenzo, T.P, Almo, S.C, Immune Function Network, New York Structural Genomics Research Consortium (NYSGRC)
登録日2014-02-28
公開日2014-03-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.335 Å)
主引用文献Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses
J. Immunol., 193, 2014
5KD7
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BU of 5kd7 by Molmil
Crystal Structure of Murine MHC-I H-2Dd in complex with Murine Beta2-Microglobulin and a Variant of Peptide (PV9) of HIV gp120 MN Isolate (IGPGRAFYV)
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Jiang, J, Natarajan, K, Margulies, D.
登録日2016-06-07
公開日2017-10-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Effects of Cross-Presentation, Antigen Processing, and Peptide Binding in HIV Evasion of T Cell Immunity.
J. Immunol., 200, 2018
6MJA
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Crystal structure of the mCD1d/xxo (JJ294) /iNKTCR ternary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Zajonc, D.M, Bitra, A, Janssens, J.
登録日2018-09-20
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14, 2019
7WCY
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BU of 7wcy by Molmil
Crystal Structure of H-2Kb with Cryptosporidium parvum gp40/15 epitope
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ...
著者Wang, Y.L, Gao, M.H, Zhang, L.X, Fan, S.H.
登録日2021-12-20
公開日2022-12-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural Analyses of a Dominant Cryptosporidium parvum Epitope Presented by H-2K b Offer New Options To Combat Cryptosporidiosis.
Mbio, 14, 2023
6CX9
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Structure of alpha-GSA[16,6P] bound by CD1d and in complex with the Va14Vb8.2 TCR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Wang, J, Zajonc, D.
登録日2018-04-02
公開日2019-04-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
4PG9
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BU of 4pg9 by Molmil
MHC Class I in complex with Sendai virus nucleoprotein peptide FAPGNYPAL
分子名称: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
著者Celie, P, Joosten, R.P, Perrakis, A, Neefjes, J.
登録日2014-05-01
公開日2015-01-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The first step of peptide selection in antigen presentation by MHC class I molecules.
Proc.Natl.Acad.Sci.USA, 112, 2015
7M72
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MHC-like protein complex structure
分子名称: (3R)-N-[(2S,3R)-1-(alpha-D-galactopyranosyloxy)-3-hydroxy-15-methylhexadecan-2-yl]-3-hydroxyheptadecanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ...
著者Thirunavukkarasu, P, Le Nours, J, Rossjohn, J.
登録日2021-03-26
公開日2021-11-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Host immunomodulatory lipids created by symbionts from dietary amino acids.
Nature, 600, 2021
1MWA
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BU of 1mwa by Molmil
2C/H-2KBM3/DEV8 ALLOGENEIC COMPLEX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2C T CELL RECEPTOR ALPHA CHAIN, ...
著者Luz, J.G, Huang, M.D, Garcia, K.C, Rudolph, M.G, Teyton, L, Wilson, I.A.
登録日2002-09-27
公開日2002-11-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural comparison of allogeneic and syngeneic T cell receptor-peptide-major histocompatibility complex complexes: a buried alloreactive mutation subtly alters peptide presentation substantially increasing V(beta) Interactions.
J.EXP.MED., 195, 2002
1BII
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BU of 1bii by Molmil
THE CRYSTAL STRUCTURE OF H-2DD MHC CLASS I IN COMPLEX WITH THE HIV-1 DERIVED PEPTIDE P18-110
分子名称: BETA-2 MICROGLOBULIN, DECAMERIC PEPTIDE, MHC CLASS I H-2DD
著者Achour, A, Persson, K, Harris, R.A, Sundback, J, Sentman, C.L, Lindqvist, Y, Schneider, G, Karre, K.
登録日1998-06-11
公開日1998-10-14
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of H-2Dd MHC class I complexed with the HIV-1-derived peptide P18-I10 at 2.4 A resolution: implications for T cell and NK cell recognition.
Immunity, 9, 1998
6H6D
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BU of 6h6d by Molmil
Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with adenovirus-derived peptide Ad10
分子名称: Beta-2-microglobulin, CHLORIDE ION, Early E1A protein, ...
著者Achour, A, Sandalova, T, Han, X.
登録日2018-07-27
公開日2019-08-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of H-2Db and H-2Dbm13 with cancer-associated Ad 10 peptide reveal that subtle changes in the peptide environment impact thermostability and alloreactivity
to be published
1S7W
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BU of 1s7w by Molmil
Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 index peptide and three of its escape variants
分子名称: Beta-2-microglobulin, Glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ...
著者Velloso, L.M, Michaelsson, J, Ljunggren, H.G, Schneider, G, Achour, A.
登録日2004-01-30
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.
J.Immunol., 172, 2004
5MZM
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BU of 5mzm by Molmil
Structure of H-2Db in complex with TEIPP APL Trh4 p3P
分子名称: Beta-2-microglobulin, Ceramide synthase 5 derived peptide Trh4 p3P, GLYCEROL, ...
著者Hafstrand, I, Achour, A, Sandalova, T.
登録日2017-02-01
公開日2018-03-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Immunogenicity of a Proline-Substituted Altered Peptide Ligand toward the Cancer-Associated TEIPP Neoepitope Trh4 Is Unrelated to Complex Stability.
J. Immunol., 200, 2018
6JQ2
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BU of 6jq2 by Molmil
Crystal Structure of H2-Kb in complex with a DPAGT1 self-peptide
分子名称: Beta-2-microglobulin, DPATG1 antigen SIIVFNLV, H-2 class I histocompatibility antigen, ...
著者Bai, P, Yin, L.
登録日2019-03-28
公開日2020-04-01
最終更新日2021-02-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
Oncoimmunology, 10, 2021
6H6H
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Crystal structures of the murine class I major histocompatibility complex H-2Dbm13 in complex with adenovirus-derived peptide Ad10
分子名称: Beta-2-microglobulin, GLYCEROL, H-2D cell surface glycoprotein, ...
著者Achour, A, Sandalova, T, Han, X.
登録日2018-07-27
公開日2019-08-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of H-2Db and H-2Dbm13 with cancer-associated Ad 10 peptide reveal that subtle changes in the peptide environment impact thermostability and alloreactivity
to be published
5JWE
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Crystal structure of H-2Db in complex with the LCMV-derived GP92-101 peptide
分子名称: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
著者Buratto, J, Badia-Martinez, D, Norstrom, M, Sandalova, T, Achour, A.
登録日2016-05-12
公開日2017-05-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity.
PLoS ONE, 12, 2017
1LD9
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THE THREE-DIMENSIONAL STRUCTURE OF AN H-2LD PEPTIDE COMPLEX EXPLAINS THE UNIQUE INTERACTION OF LD WITH BETA2M AND PEPTIDE
分子名称: BETA-2 MICROGLOBULIN, MHC CLASS I H-2LD HEAVY CHAIN, NANO-PEPTIDE
著者Balendiran, G.K, Solheim, J.C, Young, A.C.M, Hansen, T.H, Nathenson, S.G, Sacchettini, J.C.
登録日1997-04-24
公開日1998-05-06
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The three-dimensional structure of an H-2Ld-peptide complex explains the unique interaction of Ld with beta-2 microglobulin and peptide.
Proc.Natl.Acad.Sci.USA, 94, 1997
6CX5
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Structure of alpha-GSA[8,8P] bound by CD1d and in complex with the Va14Vb8.2 TCR
分子名称: (5R,6S,7S)-5,6-dihydroxy-7-(octanoylamino)-N-(8-phenyloctyl)-8-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}octanamide (non-preferred name), 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, J, Zajonc, D.
登録日2018-04-02
公開日2019-04-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019
5OQI
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Crystal Structure of a disulfide trapped single chain trimer composed of the MHC I heavy chain H-2Kb Y84C E63A mutant, beta-2microglobulin, and ovalbumin-derived peptide
分子名称: Beta-2-microglobulin,H-2 class I histocompatibility antigen, K-B alpha chain
著者Mikolajek, H, Werner, J.M, Beton, M.E.
登録日2017-08-11
公開日2018-04-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The partial dissociation of MHC class I-bound peptides exposes their N terminus to trimming by endoplasmic reticulum aminopeptidase 1.
J. Biol. Chem., 293, 2018
1HOC
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THE THREE-DIMENSIONAL STRUCTURE OF H-2DB AT 2.4 ANGSTROMS RESOLUTION: IMPLICATIONS FOR ANTIGEN-DETERMINANT SELECTION
分子名称: 9-RESIDUE PEPTIDE, BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (H2-DB) (ALPHA CHAIN)
著者Young, A.C.M, Zhang, W, Sacchettini, J.C.
登録日1994-01-02
公開日1994-04-30
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The three-dimensional structure of H-2Db at 2.4 A resolution: implications for antigen-determinant selection
Cell(Cambridge,Mass.), 76, 1994

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