3WS3
Crystal Structure of H-2D in complex with an insulin derived peptide
Summary for 3WS3
Entry DOI | 10.2210/pdb3ws3/pdb |
Related | 3WS6 |
Descriptor | H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, Insulin derived 9-mer peptide, ... (4 entities in total) |
Functional Keywords | class i mhc, major histocompatibility complex, insulin, h-2d, structural genomics, psi-biology, new york structural genomics research consortium, nysgrc, immune system |
Biological source | Mus musculus (mouse) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01899 Secreted: P01887 |
Total number of polymer chains | 6 |
Total formula weight | 89484.39 |
Authors | Kumar, P.R.,Mukherjee, G.,Samanta, D.,DiLorenzo, T.P.,Almo, S.C.,Immune Function Network,New York Structural Genomics Research Consortium (NYSGRC) (deposition date: 2014-02-28, release date: 2014-03-26, Last modification date: 2023-11-08) |
Primary citation | Lamont, D.,Mukherjee, G.,Kumar, P.R.,Samanta, D.,McPhee, C.G.,Kay, T.W.H.,Almo, S.C.,DiLorenzo, T.P.,Serreze, D.V. Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses J. Immunol., 193:2135-2146, 2014 Cited by PubMed: 25063871DOI: 10.4049/jimmunol.1400997 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.335 Å) |
Structure validation
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