3CH1

Crystal structure of H-2Db in complex with chimeric gp100

Summary for 3CH1

• Entry DOI: 10.2210/pdb3ch1/pdb
• Related: 3CCH
• Descriptor: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, nonameric peptide chimeric gp100, ... (6 entities in total)
• Functional Keywords: mhc, h-2db, glycoprotein, immune response, membrane, mhc i, transmembrane, immunoglobulin domain, secreted, disease mutation, melanin biosynthesis, immune system
• Biological source: Mus musculus (mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887
• Total number of polymer chains: 12
• Total formula weight: 182503.71

Authors

Badia-Martinez, D.,Achour, A. (deposition date: 2008-03-06, release date: 2009-03-31, Last modification date: 2011-07-13)

• Primary citation: van Stipdonk, M.J.,Badia-Martinez, D.,Sluijter, M.,Offringa, R.,van Hall, T.,Achour, A.; Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.; Cancer Res., 69:7784-7792, 2009; PubMed: 19789338; DOI: 10.1158/0008-5472.CAN-09-1724

Experimental method

X-RAY DIFFRACTION (2.3 Å)