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PDB: 165 件

1S32
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Molecular Recognition of the Nucleosomal 'Supergroove'
分子名称: 2-(2-CARBAMOYLMETHOXY-ETHOXY)-ACETAMIDE, 3-AMINO-(DIMETHYLPROPYLAMINE), 4-AMINO-(1-METHYLIMIDAZOLE)-2-CARBOXYLIC ACID, ...
著者Edayathumangalam, R.S, Weyermann, P, Gottesfeld, J.M, Dervan, P.B, Luger, K.
登録日2004-01-12
公開日2004-05-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Molecular Recognition of the Nucleosomal 'Supergroove'
Proc.Natl.Acad.Sci.USA, 101, 2004
3UTA
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Crystal Structure of Nucleosome Core Particle Assembled with an Alpha-Satellite Sequence Containing Two TTAAA elements (NCP-TA2)
分子名称: 145-mer DNA, CHLORIDE ION, Histone H2A, ...
著者Chua, E.Y.D, Vasudevan, D, Davey, G.E, Wu, B, Davey, C.A.
登録日2011-11-25
公開日2012-04-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献The mechanics behind DNA sequence-dependent properties of the nucleosome
Nucleic Acids Res., 40, 2012
6WZ5
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BU of 6wz5 by Molmil
Bridging of double-strand DNA break activates PARP2/HPF1 to modify chromatin
分子名称: DNA (153-MER), Histone H2A, Histone H2B 1.1, ...
著者Halic, M, Bilokapic, S.
登録日2020-05-13
公開日2020-09-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Nature, 585, 2020
3UTB
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Crystal Structure of Nucleosome Core Particle Assembled with the 146b Alpha-Satellite Sequence (NCP146b)
分子名称: 146-mer DNA, Histone H2A, Histone H2B 1.1, ...
著者Chua, E.Y.D, Vasudevan, D, Davey, G.E, Wu, B, Davey, C.A.
登録日2011-11-25
公開日2012-04-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The mechanics behind DNA sequence-dependent properties of the nucleosome
Nucleic Acids Res., 40, 2012
3UT9
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BU of 3ut9 by Molmil
Crystal Structure of Nucleosome Core Particle Assembled with a Palindromic Widom '601' Derivative (NCP-601L)
分子名称: 145-mer DNA, CHLORIDE ION, Histone H2A, ...
著者Chua, E.Y.D, Vasudevan, D, Davey, G.E, Wu, B, Davey, C.A.
登録日2011-11-25
公開日2012-04-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The mechanics behind DNA sequence-dependent properties of the nucleosome
Nucleic Acids Res., 40, 2012
3MGR
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BU of 3mgr by Molmil
Binding of Rubidium ions to the Nucleosome Core Particle
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
著者Mohideen, K, Muhammad, R, Davey, C.A.
登録日2010-04-07
公開日2010-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Perturbations in nucleosome structure from heavy metal association.
Nucleic Acids Res., 38, 2010
8G88
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BU of 8g88 by Molmil
Human Oct4 bound to nucleosome with human nMatn1 sequence
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
8G86
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Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of nucleosome)
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
5OMX
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BU of 5omx by Molmil
X-ray Structure of the H2A-N38C Nucleosome Core Particle
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
著者Frouws, T.D, Richmond, T.J.
登録日2017-08-02
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Site-Specific Disulfide Crosslinked Nucleosomes with Enhanced Stability.
J. Mol. Biol., 430, 2018
6YN1
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BU of 6yn1 by Molmil
Crystal structure of histone chaperone APLF acidic domain bound to the histone H2A-H2B-H3-H4 octamer
分子名称: Aprataxin and PNK-like factor, CHLORIDE ION, GLYCEROL, ...
著者Corbeski, I, Guo, X, Van Ingen, H, Sixma, T.K.
登録日2020-04-10
公開日2021-11-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF.
Sci Adv, 8, 2022
4KHA
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BU of 4kha by Molmil
Structural basis of histone H2A-H2B recognition by the essential chaperone FACT
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Histone H2A, ...
著者Hondele, M, Halbach, F, Hassler, M, Ladurner, A.G.
登録日2013-04-30
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis of histone H2A-H2B recognition by the essential chaperone FACT.
Nature, 499, 2013
4XZQ
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BU of 4xzq by Molmil
Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad axis
分子名称: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
著者Dechassa, M.L, Luger, K, Chatterjee, N, North, J.A, Manohar, M, Prasad, R, Ottessen, J.J, Poirier, M.G, Bartholomew, B.
登録日2015-02-04
公開日2015-10-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF.
Mol.Cell.Biol., 35, 2015
4J8W
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BU of 4j8w by Molmil
X-ray structure of NCP145 with chlorido(eta-6-p-cymene)(N-fluorophenyl-2-pyridinecarbothioamide)osmium(II)
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Adhireksan, Z, Davey, C.A.
登録日2013-02-15
公開日2013-04-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
3MGP
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BU of 3mgp by Molmil
Binding of Cobalt ions to the Nucleosome Core Particle
分子名称: CHLORIDE ION, COBALT (II) ION, DNA (147-MER), ...
著者Mohideen, K, Muhammad, R, Davey, C.A.
登録日2010-04-07
公開日2010-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Perturbations in nucleosome structure from heavy metal association.
Nucleic Acids Res., 38, 2010
3LZ0
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BU of 3lz0 by Molmil
Crystal Structure of Nucleosome Core Particle Composed of the Widom 601 DNA Sequence (orientation 1)
分子名称: CHLORIDE ION, DNA (145-MER), Histone H2A, ...
著者Vasudevan, D, Chua, E.Y.D, Davey, C.A.
登録日2010-03-01
公開日2010-09-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of nucleosome core particles containing the '601' strong positioning sequence
J.Mol.Biol., 403, 2010
3LZ1
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BU of 3lz1 by Molmil
Crystal Structure of Nucleosome Core Particle Composed of the Widom 601 DNA Sequence (orientation 2)
分子名称: CHLORIDE ION, DNA (145-MER), Histone H2A, ...
著者Vasudevan, D, Chua, E.Y.D, Davey, C.A.
登録日2010-03-01
公開日2010-09-15
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of nucleosome core particles containing the '601' strong positioning sequence
J.Mol.Biol., 403, 2010
3MNN
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BU of 3mnn by Molmil
A Ruthenium Antitumour Agent Forms Specific Histone Protein Adducts in the Nucleosome Core
分子名称: 1,3,5-triaza-7-phosphatricyclo[3.3.1.1~3,7~]decane, 1-methyl-4-(1-methylethyl)benzene, DNA (145-MER), ...
著者Ong, M.S, Davey, C.A.
登録日2010-04-22
公開日2011-04-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core
Chemistry, 17, 2011
4Z66
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BU of 4z66 by Molmil
Nucleosome disassembly by RSC and SWI/SNF is enhanced by H3 acetylation near the nucleosome dyad axis
分子名称: DNA (147-MER), Histone H2A, Histone H2B 1.1, ...
著者Dechassa, M.L, Luger, K, Chatterjee, N, North, J.A, Manohar, M, Prasad, R, Ottessen, J.J, Poirier, M.G, Bartholomew, B.
登録日2015-04-03
公開日2015-10-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Histone Acetylation near the Nucleosome Dyad Axis Enhances Nucleosome Disassembly by RSC and SWI/SNF.
Mol.Cell.Biol., 35, 2015
7OHC
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BU of 7ohc by Molmil
Cryo-EM structure of nucleosome core particle composed of the Widom 601 DNA sequence
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Wang, H, Cramer, P.
登録日2021-05-10
公開日2021-07-28
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structures and implications of TBP-nucleosome complexes.
Proc.Natl.Acad.Sci.USA, 118, 2021
4J8V
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BU of 4j8v by Molmil
X-ray structure of NCP145 with bound chlorido(eta-6-p-cymene)(N-phenyl-2-pyridinecarbothioamide)ruthenium(II)
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Adhireksan, Z, Davey, C.A.
登録日2013-02-15
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
CHEM SCI, 4, 2013
5CP6
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Nucleosome Core Particle with Adducts from the Anticancer Compound, [(eta6-5,8,9,10-tetrahydroanthracene)Ru(ethylenediamine)Cl][PF6]
分子名称: (ethane6-5,8,9,10-tetrahydroanthracene)Ru(II)(ethylene-diamine)Cl, DNA (145-MER), Histone H2A, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2015-07-21
公開日2016-06-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode.
Angew.Chem.Int.Ed.Engl., 55, 2016
5XF6
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BU of 5xf6 by Molmil
Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having an ethylenediamine linker
分子名称: DNA (145-MER), ETHANE-1,2-DIAMINE, Histone H2A, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
3MGQ
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BU of 3mgq by Molmil
Binding of Nickel ions to the Nucleosome Core Particle
分子名称: CHLORIDE ION, DNA (147-MER), Histone H2A, ...
著者Mohideen, K, Muhammad, R, Davey, C.A.
登録日2010-04-07
公開日2010-06-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Perturbations in nucleosome structure from heavy metal association.
Nucleic Acids Res., 38, 2010
2NZD
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Nucleosome core particle containing 145 bp of DNA
分子名称: DNA (145-MER), Histone H2B, Histone H3, ...
著者Ong, M.S, Richmond, T.J, Davey, C.A.
登録日2006-11-23
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献DNA stretching and extreme kinking in the nucleosome core
J.Mol.Biol., 368, 2007
8PEO
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BU of 8peo by Molmil
H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex
分子名称: (2R)-2-amino-3-(2-dimethylaminoethylsulfanyl)propanoic acid, Histone H2A, Histone H2B 1.1, ...
著者Koutna, E, Kouba, T, Veverka, V.
登録日2023-06-14
公開日2023-08-16
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023

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