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PDB: 12 件
4LAY
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BU of 4lay by Molmil
Crystal Structure Analysis of FKBP52, Complex with I63
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP4, {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid
著者Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F.
登録日2013-06-20
公開日2013-08-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge.
J.Mol.Biol., 425, 2013
4DRJ
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BU of 4drj by Molmil
o-crystal structure of the PPIase domain of FKBP52, Rapamycin and the FRB fragment of mTOR
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP4, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, SULFATE ION, ...
著者Maerz, A.M, Bracher, A, Hausch, F.
登録日2012-02-17
公開日2013-02-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin.
Mol.Cell.Biol., 33, 2013
4LAV
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BU of 4lav by Molmil
Crystal Structure Analysis of FKBP52, Crystal Form II
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP4, SULFATE ION
著者Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F.
登録日2013-06-20
公開日2013-08-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge.
J.Mol.Biol., 425, 2013
1Q1C
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BU of 1q1c by Molmil
Crystal structure of N(1-260) of human FKBP52
分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, FK506-binding protein 4
著者Wu, B, Li, P, Lou, Z, Ding, Y, Shu, C, Shen, B, Rao, Z.
登録日2003-07-18
公開日2004-06-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex
Proc.Natl.Acad.Sci.USA, 101, 2004
4LAX
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BU of 4lax by Molmil
Crystal Structure Analysis of FKBP52, Complex with FK506
分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F.
登録日2013-06-20
公開日2013-08-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.007 Å)
主引用文献Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge.
J.Mol.Biol., 425, 2013
6RCY
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BU of 6rcy by Molmil
CRYSTAL STRUCTURE OF FK1 DOMAIN OF FKBP52 IN COMPLEX WITH A BIO-INSPIRED HYBRID FLUORESCENT LIGAND
分子名称: (2~{S})-5-carbamimidamido-2-[[(2~{S})-2-[[(2~{S})-1-[5-(dimethylamino)naphthalen-1-yl]sulfonylpiperidin-2-yl]carbonylamino]-4-phenyl-butanoyl]amino]pentanoic acid, Peptidyl-prolyl cis-trans isomerase FKBP4
著者Li de la Sierra-Gallay, I, Byrne, C.
登録日2019-04-12
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Bioinspired Hybrid Fluorescent Ligands for the FK1 Domain of FKBP52.
J.Med.Chem., 63, 2020
1N1A
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BU of 1n1a by Molmil
Crystal Structure of the N-terminal domain of human FKBP52
分子名称: FKBP52
著者Li, P, Ding, Y, Wu, B, Shu, C, Shen, B, Rao, Z.
登録日2002-10-16
公開日2002-12-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the N-terminal domain of human FKBP52.
Acta Crystallogr.,Sect.D, 59, 2003
4LAW
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BU of 4law by Molmil
Crystal Structure Analysis of FKBP52, Crystal Form III
分子名称: DIMETHYL SULFOXIDE, Peptidyl-prolyl cis-trans isomerase FKBP4
著者Bracher, A, Kozany, C, Haehle, A, Wild, P, Zacharias, M, Hausch, F.
登録日2013-06-20
公開日2013-08-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of the Free and Ligand-Bound FK1-FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge.
J.Mol.Biol., 425, 2013
1P5Q
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BU of 1p5q by Molmil
Crystal Structure of FKBP52 C-terminal Domain
分子名称: FK506-binding protein 4, SULFATE ION
著者Wu, B, Li, P, Lou, Z, Shu, C, Ding, Y, Shen, B, Rao, Z.
登録日2003-04-28
公開日2004-06-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex
Proc.Natl.Acad.Sci.USA, 101, 2004
1QZ2
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BU of 1qz2 by Molmil
Crystal Structure of FKBP52 C-terminal Domain complex with the C-terminal peptide MEEVD of Hsp90
分子名称: 5-mer peptide from Heat shock protein HSP 90, FK506-binding protein 4
著者Wu, B, Li, P, Lou, Z, Liu, Y, Ding, Y, Shu, C, Shen, B, Rao, Z.
登録日2003-09-15
公開日2004-06-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex.
Proc.Natl.Acad.Sci.USA, 101, 2004
4TW8
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BU of 4tw8 by Molmil
The Fk1-Fk2 domains of FKBP52 in complex with iFit-FL
分子名称: 2-(5-{[({3-[(1R)-1-[({(2S)-1-[(2S)-2-[(1S)-cyclohex-2-en-1-yl]-2-(3,4,5-trimethoxyphenyl)acetyl]piperidin-2-yl}carbonyl)oxy]-3-(3,4-dimethoxyphenyl)propyl]phenoxy}acetyl)amino]methyl}-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, Peptidyl-prolyl cis-trans isomerase FKBP4
著者Gaali, S, Kirschner, A, Cuboni, S, Hartmann, J, Kozany, C, Balsevich, G, Namendorf, C, Fernandez-Vizarra, P, Almeida, O.F.X, Ruehter, G, Uhr, M, Schmidt, M.V, Touma, C, Bracher, A, Hausch, F.
登録日2014-06-30
公開日2014-11-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Selective inhibitors of the FK506-binding protein 51 by induced fit.
Nat.Chem.Biol., 11, 2015
8FFV
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BU of 8ffv by Molmil
Cryo-EM structure of the GR-Hsp90-FKBP52 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ...
著者Noddings, C.M, Agard, D.A.
登録日2022-12-10
公開日2023-11-01
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor.
Nat.Struct.Mol.Biol., 30, 2023

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件を2024-06-26に公開中

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