1QZ2

Crystal Structure of FKBP52 C-terminal Domain complex with the C-terminal peptide MEEVD of Hsp90

Summary for 1QZ2

DescriptorFK506-binding protein 4, 5-mer peptide from Heat shock protein HSP 90 (3 entities in total)
Functional Keywordsisomerase, rotamase, chaperone, heat shock, isomerase-chaperone complex, isomerase/chaperone
Biological sourceHomo sapiens (human)
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Cellular locationCytoplasm, cytosol (By similarity) Q02790
Cytoplasm P08238
Total number of polymer chains5
Total molecular weight116449.75
Authors
Wu, B.,Li, P.,Lou, Z.,Liu, Y.,Ding, Y.,Shu, C.,Shen, B.,Rao, Z. (deposition date: 2003-09-15, release date: 2004-06-22, Last modification date: 2011-07-13)
Primary citation
Wu, B.,Li, P.,Liu, Y.,Lou, Z.,Ding, Y.,Shu, C.,Ye, S.,Bartlam, M.,Shen, B.,Rao, Z.
3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex.
Proc.Natl.Acad.Sci.USA, 101:8348-8353, 2004
PubMed: 15159550 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.0305969101
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.274316.8%7.0%0.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution