Crystal Structure of FKBP52 C-terminal Domain complex with the C-terminal peptide MEEVD of Hsp90

Summary for 1QZ2

DescriptorFK506-binding protein 4, 5-mer peptide from Heat shock protein HSP 90 (3 entities in total)
Functional Keywordsisomerase, rotamase, chaperone, heat shock, isomerase-chaperone complex, isomerase/chaperone
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm, cytosol (By similarity) Q02790
Cytoplasm P08238
Total number of polymer chains5
Total molecular weight116449.75
Wu, B.,Li, P.,Lou, Z.,Liu, Y.,Ding, Y.,Shu, C.,Shen, B.,Rao, Z. (deposition date: 2003-09-15, release date: 2004-06-22, Last modification date: 2011-07-13)
Primary citation
Wu, B.,Li, P.,Liu, Y.,Lou, Z.,Ding, Y.,Shu, C.,Ye, S.,Bartlam, M.,Shen, B.,Rao, Z.
3D structure of human FK506-binding protein 52: Implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex.
Proc.Natl.Acad.Sci.USA, 101:8348-8353, 2004
PubMed: 15159550 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.0305969101
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.274316.8%7.0%0.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution