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PDB: 57 件

2MQF
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NMR structure of spider toxin-TRTX-Hhn2b
分子名称: Mu-theraphotoxin-Hhn2b
著者Klint, J.K, Chin, Y.K.Y, Mobli, M.
登録日2014-06-19
公開日2015-07-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Rational Engineering Defines a Molecular Switch That Is Essential for Activity of Spider-Venom Peptides against the Analgesics Target NaV1.7
Mol.Pharmacol., 88, 2015
2MPQ
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Solution structure of the sodium channel toxin Hd1a
分子名称: Hd1a
著者Klint, J.K, Mobli, M, King, G.F.
登録日2014-06-01
公開日2015-03-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach.
Br.J.Pharmacol., 172, 2015
2MXM
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NMR solution structure of TRTX-Tp1a from the tarantula Thrixopelma pruriens
分子名称: entity
著者Rosengren, K.
登録日2015-01-08
公開日2015-06-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Identification and Characterization of ProTx-III [ mu-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens.
Mol.Pharmacol., 88, 2015
2N6O
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Structure of spider-venom peptide Hm1a
分子名称: Kappa-theraphotoxin-Hm1a
著者Undheim, E.A.B, King, G.F, Mobli, M.
登録日2015-08-27
公開日2016-09-07
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure of spider-venom peptide Hm1a
To be Published
3J5Q
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Structure of TRPV1 ion channel in complex with DkTx and RTX determined by single particle electron cryo-microscopy
分子名称: Kappa-theraphotoxin-Cg1a 1, Transient receptor potential cation channel subfamily V member 1
著者Liao, M, Cao, E, Julius, D, Cheng, Y.
登録日2013-10-28
公開日2013-12-04
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献TRPV1 structures in distinct conformations reveal activation mechanisms.
Nature, 504, 2013
7K48
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Structure of NavAb/Nav1.7-VS2A chimera trapped in the resting state by tarantula toxin m3-Huwentoxin-IV
分子名称: Maltose/maltodextrin-binding periplasmic protein,Ion transport protein,Sodium channel protein type 9 subunit alpha chimera, Mu-theraphotoxin-Hs2a
著者Wisedchaisri, G, Tonggu, L, Gamal El-Din, T.M, McCord, E, Zheng, N, Catterall, W.A.
登録日2020-09-15
公開日2020-12-02
最終更新日2021-01-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural Basis for High-Affinity Trapping of the Na V 1.7 Channel in Its Resting State by Tarantula Toxin.
Mol.Cell, 81, 2021
6W6O
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NaChBac-Nav1.7VSDII chimera and HWTX-IV complex
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Huwentoxin-IV, NaChBac-Nav1.7VSDII chimera
著者Yan, N, Gao, S.
登録日2020-03-17
公開日2020-06-24
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na + channels in nanodisc.
Proc.Natl.Acad.Sci.USA, 117, 2020
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件を2024-07-10に公開中

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