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PDB: 15 件

5MQI
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Crystal structure of the N-terminal domain of human Timeless
分子名称: Protein timeless homolog,Protein timeless homolog, SULFATE ION
著者Holzer, S, Kilkenny, M.L, Pellegrini, L.
登録日2016-12-20
公開日2017-03-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.847 Å)
主引用文献Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin.
Nucleic Acids Res., 45, 2017
6XWX
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BU of 6xwx by Molmil
Crystal structure of the Tof1-Csm3 complex
分子名称: Chromosome segregation in meiosis protein, Uncharacterized protein,Uncharacterized protein
著者Grabarczyk, D.B.
登録日2020-01-24
公開日2020-05-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure and interactions of the Tof1-Csm3 (Timeless-Tipin) fork protection complex.
Nucleic Acids Res., 48, 2020
8XGC
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Structure of yeast replisome associated with FACT and histone hexamer, Composite map
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ...
著者Li, N, Gao, Y, Yu, D, Gao, N, Zhai, Y.
登録日2023-12-15
公開日2024-02-14
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Parental histone transfer caught at the replication fork.
Nature, 627, 2024
8DD7
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The Cryo-EM structure of Drosophila Cryptochrome in complex with Timeless
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Methylated-DNA--protein-cysteine methyltransferase,Cryptochrome-1 fusion, Protein timeless,Methylated-DNA--protein-cysteine methyltransferase fusion
著者Feng, S, Lin, C, DeOliveira, C.C, Crane, B.R.
登録日2022-06-17
公開日2023-02-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryptochrome-Timeless structure reveals circadian clock timing mechanisms.
Nature, 617, 2023
6SKL
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Cryo-EM structure of the CMG Fork Protection Complex at a replication fork - Conformation 1
分子名称: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA fork, ...
著者Yeeles, J, Baretic, D, Jenkyn-Bedford, M.
登録日2019-08-16
公開日2020-05-06
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork.
Mol.Cell, 78, 2020
8KG6
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Yeast replisome in state I
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ...
著者Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z.
登録日2023-08-17
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Synergism between CMG helicase and leading strand DNA polymerase at replication fork.
Nat Commun, 14, 2023
8OUW
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Cryo-EM structure of CMG helicase bound to TIM-1/TIPN-1 and homodimeric DNSN-1 on fork DNA (Caenorhabditis elegans)
分子名称: Cell division control protein 45 homolog, DNA Lagging Strand Template, DNA Leading Strand Template, ...
著者Jenkyn-Bedford, M, Yeeles, J.T.P, Labib, K.P.M.
登録日2023-04-25
公開日2023-08-16
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in Caenorhabditis elegans.
Science, 381, 2023
7PMK
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S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation I)
分子名称: Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA helicase, ...
著者Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D.
登録日2021-09-02
公開日2021-11-10
最終更新日2022-02-02
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
7PLO
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H. sapiens replisome-CUL2/LRR1 complex
分子名称: Cell division control protein 45 homolog, Claspin, Cullin-2, ...
著者Jones, M.J, Yeeles, J.T.P, Deegan, T.D, Jenkyn-Bedford, M.
登録日2021-09-01
公開日2021-11-10
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
7PMN
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S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation II)
分子名称: Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha-binding protein, ...
著者Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D.
登録日2021-09-02
公開日2021-11-10
最終更新日2022-01-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A conserved mechanism for regulating replisome disassembly in eukaryotes.
Nature, 600, 2021
7PFO
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Core human replisome
分子名称: Cell division control protein 45 homolog, Claspin, DNA polymerase epsilon catalytic subunit A, ...
著者Jones, M.J, Yeeles, J.T.P.
登録日2021-08-11
公開日2021-11-10
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of a human replisome shows the organisation and interactions of a DNA replication machine.
Embo J., 40, 2021
8B9B
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S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
分子名称: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
著者Jones, M.L, Yeeles, J.T.P.
登録日2022-10-05
公開日2023-08-09
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8B9A
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BU of 8b9a by Molmil
S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
分子名称: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
著者Jones, M.L, Yeeles, J.T.P.
登録日2022-10-05
公開日2023-08-09
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8B9C
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BU of 8b9c by Molmil
S. cerevisiae pol alpha - replisome complex
分子名称: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ...
著者Jones, M.L, Yeeles, J.T.P.
登録日2022-10-05
公開日2023-08-09
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023
8B9D
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BU of 8b9d by Molmil
Human replisome bound by Pol Alpha
分子名称: Cell division control protein 45 homolog, Claspin, DNA Molecule, ...
著者Jones, M.L, Yeeles, J.T.P.
登録日2022-10-05
公開日2023-08-09
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication.
Mol.Cell, 83, 2023

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件を2024-06-12に公開中

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