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PDB: 291 件
4JKR
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Crystal Structure of E. coli RNA Polymerase in complex with ppGpp
分子名称: DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA', DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, Wang, Y, Steitz, T.A.
登録日2013-03-11
公開日2013-05-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献The mechanism of E. coli RNA polymerase regulation by ppGpp is suggested by the structure of their complex.
Mol.Cell, 50, 2013
8Y6U
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BU of 8y6u by Molmil
Cryo-EM structure of E.coli transcription initiation complex with transcription factor GcvA
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Lin, W, Shi, J.
登録日2024-02-03
公開日2024-06-05
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献NMR analysis of a loop-bulge structure of UUCGA pentaloop.
Biochem.Biophys.Res.Commun., 691, 2024
4LLG
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BU of 4llg by Molmil
Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex
分子名称: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Bae, B, Darst, S.A.
登録日2013-07-09
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.7936 Å)
主引用文献Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JK1
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BU of 4jk1 by Molmil
X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with Guanosine tetraphosphate (ppGpp)
分子名称: Escherichia coli RNA polymerase alpha subunit, Escherichia coli RNA polymerase beta subunit, Escherichia coli RNA polymerase beta' subunit, ...
著者Murakami, K.S.
登録日2013-03-09
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Differential regulation by ppGpp versus pppGpp in Escherichia coli.
Nucleic Acids Res., 41, 2013
4JK2
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BU of 4jk2 by Molmil
X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with guanosine pentaphosphate (pppGpp)
分子名称: Escherichia coli RNA polymerase alpha subunit, Escherichia coli RNA polymerase beta subunit, Escherichia coli RNA polymerase beta' subunit, ...
著者Murakami, K.S.
登録日2013-03-09
公開日2013-04-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.201 Å)
主引用文献Differential regulation by ppGpp versus pppGpp in Escherichia coli.
Nucleic Acids Res., 41, 2013
4LJZ
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BU of 4ljz by Molmil
Crystal Structure Analysis of the E.coli holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Bae, B, Darst, S.A.
登録日2013-07-05
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5871 Å)
主引用文献Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KN4
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BU of 4kn4 by Molmil
X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Benzoxazinorifamycin-2b
分子名称: Benzoxazinorifamycin-2b, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Murakami, K.S.
登録日2013-05-08
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.965 Å)
主引用文献X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins.
J.Med.Chem., 56, 2013
4KN7
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X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Benzoxazinorifamycin-2c
分子名称: Benzoxazinorifamycin-2c, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Murakami, K.S.
登録日2013-05-08
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.686 Å)
主引用文献X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins.
J.Med.Chem., 56, 2013
4LK0
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BU of 4lk0 by Molmil
Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex
分子名称: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Bae, B, Darst, S.A.
登録日2013-07-05
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.9103 Å)
主引用文献Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
4KMU
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BU of 4kmu by Molmil
X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Rifampin
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Murakami, K.S.
登録日2013-05-08
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.85 Å)
主引用文献X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins.
J.Med.Chem., 56, 2013
4MEX
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BU of 4mex by Molmil
Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H.
登録日2013-08-27
公開日2014-05-21
最終更新日2014-06-25
実験手法X-RAY DIFFRACTION (3.902 Å)
主引用文献Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3, 2014
7KHI
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BU of 7khi by Molmil
Escherichia coli RNA polymerase and rrnBP1 promoter complex with DksA/ppGpp
分子名称: CHAPSO, DNA (28-MER), DNA (36-MER), ...
著者Shin, Y, Qayyum, M.Z, Murakami, K.S.
登録日2020-10-21
公開日2020-10-28
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
7L7B
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BU of 7l7b by Molmil
Clostridioides difficile RNAP with fidaxomicin
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Boyaci, H, Campbell, E.A, Darst, S.A, Chen, J.
登録日2020-12-28
公開日2022-02-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile.
Nature, 604, 2022
7MLB
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BU of 7mlb by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex with 5nt RNA
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*AP*GP*GP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*TP*GP*CP*AP*TP*CP*CP*CP*TP*GP*AP*GP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Liu, Y, Ebright, R.H.
登録日2021-04-28
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural and mechanistic basis of reiterative transcription initiation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7MLI
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BU of 7mli by Molmil
Crystal structure of Thermus thermophilus reiterative transcription complex with 5nt oligo-C RNA
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*CP*TP*AP*CP*GP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*CP*GP*TP*AP*GP*GP*GP*CP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Liu, Y, Ebright, R.H.
登録日2021-04-28
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural and mechanistic basis of reiterative transcription initiation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7MLJ
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BU of 7mlj by Molmil
Crystal structure of Thermus thermophilus reiterative transcription complex with 4nt oligo-G RNA
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*GP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*CP*GP*TP*GP*CP*CP*CP*TP*GP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Liu, Y, Ebright, R.H.
登録日2021-04-28
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.75 Å)
主引用文献Structural and mechanistic basis of reiterative transcription initiation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7MKJ
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BU of 7mkj by Molmil
Cryo-EM structure of Escherichia coli RNA polymerase bound to T7A1 promoter DNA
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Saecker, R.M, Darst, S.A, Chen, J.
登録日2021-04-23
公開日2021-09-29
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MKD
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BU of 7mkd by Molmil
Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 1)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Saecker, R.M, Darst, S.A, Chen, J.
登録日2021-04-23
公開日2021-09-29
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MKE
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BU of 7mke by Molmil
Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 2)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Saecker, R.M, Darst, S.A, Chen, J.
登録日2021-04-23
公開日2021-09-29
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MKI
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BU of 7mki by Molmil
Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR (-5G to C) promoter DNA
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Saecker, R.M, Darst, S.A, Chen, J.
登録日2021-04-23
公開日2021-09-29
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
7KIF
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BU of 7kif by Molmil
Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription factor
分子名称: DNA (55-MER), DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Lilic, M, Darst, S.A, Campbell, E.A.
登録日2020-10-23
公開日2021-04-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
7KIM
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BU of 7kim by Molmil
Mycobacterium tuberculosis WT RNAP transcription closed promoter complex with WhiB7 transcription factor
分子名称: DNA (45-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Lilic, M, Darst, S.A, Campbell, E.A.
登録日2020-10-23
公開日2021-04-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
7KIN
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Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter
分子名称: DNA (49-MER), DNA (54-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Lilic, M, Darst, S.A, Campbell, E.A.
登録日2020-10-23
公開日2021-04-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7.
Mol.Cell, 81, 2021
7N4E
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BU of 7n4e by Molmil
Escherichia coli sigma 70-dependent paused transcription elongation complex
分子名称: 5'-R(*UP*UP*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3', DNA (61-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Molodtsov, V, Su, M, Ebright, R.H.
登録日2021-06-04
公開日2022-06-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural and mechanistic basis of sigma-dependent transcriptional pausing.
Proc.Natl.Acad.Sci.USA, 119, 2022
6VVS
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BU of 6vvs by Molmil
Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with antibiotic Sorangicin
分子名称: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ...
著者Lilic, M, Braffman, N, Darst, S.A, Campbell, E.A.
登録日2020-02-18
公開日2020-10-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.112 Å)
主引用文献The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Proc.Natl.Acad.Sci.USA, 117, 2020

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件を2024-08-07に公開中

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