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PDB: 291 件
6PFJ
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Structure of S. venezuelae RsiG-WhiG-(ci-di-GMP) complex, P64 crystal form
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor
著者Schumacher, M.A.
登録日2019-06-21
公開日2019-11-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces.
Mol.Cell, 77, 2020
6PFV
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BU of 6pfv by Molmil
Structure of S. venezuelae RisG-WhiG-c-di-GMP complex: orthorhombic crystal form
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor
著者Schumacher, M.A.
登録日2019-06-22
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces.
Mol.Cell, 77, 2020
1ZYR
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BU of 1zyr by Molmil
Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase omega chain, ...
著者Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E.
登録日2005-06-10
公開日2005-09-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation.
Cell(Cambridge,Mass.), 122, 2005
5XJ0
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BU of 5xj0 by Molmil
T. thermophilus RNA polymerase holoenzyme bound with gp39 and gp76
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Ooi, W.Y, Murayama, Y, Mekler, V, Minakhin, L, Severinov, K, Yokoyama, S, Sekine, S.
登録日2017-04-28
公開日2017-12-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (4.004 Å)
主引用文献A Thermus phage protein inhibits host RNA polymerase by preventing template DNA strand loading during open promoter complex formation
Nucleic Acids Res., 46, 2018
4MEY
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BU of 4mey by Molmil
Crystal structure of Escherichia coli RNA polymerase holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H.
登録日2013-08-27
公開日2014-05-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.948 Å)
主引用文献Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3, 2014
8AD1
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BU of 8ad1 by Molmil
RNA polymerase at U-rich pause bound to RNA putL triple mutant - pause prone, closed clamp state
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Dey, S, Weixlbaumer, A.
登録日2022-07-07
公開日2022-10-19
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into RNA-mediated transcription regulation in bacteria.
Mol.Cell, 82, 2022
7P5X
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BU of 7p5x by Molmil
Mycobacterial RNAP with transcriptional activator PafBC
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Mueller, A.U, Kummer, E, Schilling, C.M, Ban, N, Weber-Ban, E.
登録日2021-07-15
公開日2021-12-22
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Transcriptional control of mycobacterial DNA damage response by sigma adaptation.
Sci Adv, 7, 2021
1L9Z
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BU of 1l9z by Molmil
Thermus aquaticus RNA Polymerase Holoenzyme/Fork-Junction Promoter DNA Complex at 6.5 A Resolution
分子名称: MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ...
著者Murakami, K.S, Masuda, S, Campbell, E.A, Muzzin, O, Darst, S.A.
登録日2002-03-27
公開日2002-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (6.5 Å)
主引用文献Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex.
Science, 296, 2002
8FTD
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BU of 8ftd by Molmil
Structure of Escherichia coli CedA in complex with transcription initiation complex
分子名称: CHAPSO, Cell division activator CedA, DNA-directed RNA polymerase subunit alpha, ...
著者Liu, M, Vassyliev, N, Nudler, E.
登録日2023-01-11
公開日2024-01-10
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献General transcription factor from Escherichia coli with a distinct mechanism of action.
Nat.Struct.Mol.Biol., 31, 2024
3IYD
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BU of 3iyd by Molmil
Three-dimensional EM structure of an intact activator-dependent transcription initiation complex
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ...
著者Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L.
登録日2009-08-01
公開日2009-11-10
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (19.799999 Å)
主引用文献Three-dimensional EM structure of an intact activator-dependent transcription initiation complex
Proc.Natl.Acad.Sci.USA, 106, 2009
8DY7
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BU of 8dy7 by Molmil
Streptomyces venezuelae RNAP transcription open promoter complex with WhiA and WhiB transcription factors
分子名称: DNA (71-MER), DNA (78-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Lilic, M, Campbell, E.A.
登録日2022-08-03
公開日2023-03-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DY9
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BU of 8dy9 by Molmil
Streptomyces venezuelae RNAP unconstrained open promoter complex with WhiA and WhiB transcription factors
分子名称: DNA (38-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Lilic, M, Campbell, E.A.
登録日2022-08-03
公開日2023-03-01
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
Proc.Natl.Acad.Sci.USA, 120, 2023
3DXJ
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BU of 3dxj by Molmil
Crystal structure of thermus thermophilus rna polymerase holoenzyme in complex with the antibiotic myxopyronin
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, BACTERIAL RNA POLYMERASE BETA SUBUNIT; CHAIN C, M, ...
著者Das, K, Arnold, E.
登録日2008-07-24
公開日2008-10-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The RNA polymerase "switch region" is a target for inhibitors.
Cell(Cambridge,Mass.), 135, 2008
3EQL
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BU of 3eql by Molmil
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic myxopyronin
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Vassylyev, D.G, Vassylyeva, M.N, Artsimovitch, I.
登録日2008-09-30
公開日2008-10-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Transcription inactivation through local refolding of the RNA polymerase structure.
Nature, 457, 2009
1SMY
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BU of 1smy by Molmil
Structural basis for transcription regulation by alarmone ppGpp
分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
著者Artsimovitch, I, Patlan, V, Sekine, S, Vassylyeva, M.N, Hosaka, T, Ochi, K, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-03-10
公開日2004-05-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for transcription regulation by alarmone ppGpp
Cell(Cambridge,Mass.), 117, 2004
4G7H
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BU of 4g7h by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex
分子名称: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', DNA-directed RNA polymerase subunit alpha, ...
著者Zhang, Y, Ebright, R.H.
登録日2012-07-20
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of transcription initiation.
Science, 338, 2012
4G7O
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BU of 4g7o by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex containing 2 nt of RNA
分子名称: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-R(*GP*A)-3', ...
著者Zhang, Y, Ebright, R.H.
登録日2012-07-20
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.993 Å)
主引用文献Structural basis of transcription initiation.
Science, 338, 2012
4G7Z
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BU of 4g7z by Molmil
Crystal structure of Thermus thermophilus transcription initiation complex containing 5-BrU at template-strand position +1
分子名称: 5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*(BRU)P*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', DNA-directed RNA polymerase subunit alpha, ...
著者Zhang, Y, Ebright, R.H.
登録日2012-07-20
公開日2012-10-31
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.815 Å)
主引用文献Structural basis of transcription initiation.
Science, 338, 2012
1SC5
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BU of 1sc5 by Molmil
Sigma-28(FliA)/FlgM complex
分子名称: RNA polymerase sigma factor FliA, anti-sigma factor FlgM
著者Sorenson, M.K, Ray, S.S, Darst, S.A.
登録日2004-02-11
公開日2004-04-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献Crystal structure of the flagellar sigma/anti-sigma complex sigma(28)/FlgM reveals an intact sigma factor in an inactive conformation.
Mol.Cell, 14, 2004
3UGP
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BU of 3ugp by Molmil
Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TATAAT)
分子名称: 5'-D(*TP*GP*TP*AP*TP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor
著者Feklistov, A, Darst, S.A.
登録日2011-11-02
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.697 Å)
主引用文献Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit.
Cell(Cambridge,Mass.), 147, 2011
1RP3
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BU of 1rp3 by Molmil
Cocrystal structure of the flagellar sigma/anti-sigma complex, Sigma-28/FlgM
分子名称: RNA polymerase sigma factor SIGMA-28 (FliA), anti sigma factor FlgM
著者Sorenson, M.K, Ray, S.S, Darst, S.A.
登録日2003-12-02
公開日2004-04-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the Flagellar Sigma/Anti-Sigma Complex Sigma(28)/FlgM Reveals an Intact Sigma Factor in an Inactive Conformation
Mol.Cell, 14, 2004
3UGO
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BU of 3ugo by Molmil
Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element ssDNA oligo (TACAAT)
分子名称: 5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3', POTASSIUM ION, RNA polymerase sigma factor
著者Feklistov, A, Darst, S.A.
登録日2011-11-02
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.096 Å)
主引用文献Structural basis for promoter-10 element recognition by the bacterial RNA polymerase sigma subunit.
Cell(Cambridge,Mass.), 147, 2011
6BZO
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BU of 6bzo by Molmil
Mtb RNAP Holo/RbpA/Fidaxomicin/upstream fork DNA
分子名称: DNA (26-MER), DNA (32-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J.
登録日2017-12-25
公開日2018-03-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
6C06
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BU of 6c06 by Molmil
Mycobacterium tuberculosis RNAP Holo/RbpA/Fidaxomicin
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M.
登録日2017-12-27
公開日2018-03-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.15 Å)
主引用文献Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
6B6H
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BU of 6b6h by Molmil
The cryo-EM structure of a bacterial class I transcription activation complex
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Hong, C, Huang, R, Yu, Z, Steitz, T.A.
登録日2017-10-02
公開日2017-11-15
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of bacterial transcription activation.
Science, 358, 2017

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件を2024-08-07に公開中

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