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PDB: 182 件

5ILQ
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Crystal structure of truncated unliganded Aspartate Transcarbamoylase from Plasmodium falciparum
分子名称: Aspartate carbamoyltransferase, GLYCEROL, SULFATE ION
著者Lunev, S, Bosch, S.S, Batista, F.D.A, Wrenger, C, Groves, M.R.
登録日2016-03-04
公開日2016-06-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum.
Acta Crystallogr.,Sect.F, 72, 2016
3AT1
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CRYSTAL STRUCTURES OF PHOSPHONOACETAMIDE LIGATED T AND PHOSPHONOACETAMIDE AND MALONATE LIGATED R STATES OF ASPARTATE CARBAMOYLTRANSFERASE AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL PH
分子名称: ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
著者Gouaux, J.E, Lipscomb, W.N.
登録日1989-09-22
公開日1990-10-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of phosphonoacetamide ligated T and phosphonoacetamide and malonate ligated R states of aspartate carbamoyltransferase at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
1EZZ
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CRYSTAL STRUCTURE OF E. COLI ASPARTATE TRANSCARBAMOYLASE P268A MUTANT IN THE T-STATE
分子名称: ASPARTATE CARBAMOYLTRANSFERASE CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ZINC ION
著者Jin, L, Stec, B, Kantrowitz, E.R.
登録日2000-05-12
公開日2000-11-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A cis-proline to alanine mutant of E. coli aspartate transcarbamoylase: kinetic studies and three-dimensional crystal structures.
Biochemistry, 39, 2000
6OVW
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Crystal structure of ornithine carbamoyltransferase from Salmonella enterica
分子名称: GLYCEROL, Ornithine carbamoyltransferase, PHOSPHATE ION
著者Chang, C, Mesa, N, Skarina, T, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2019-05-08
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献Crystal structure of ornithine carbamoyltransferase from Salmonella enterica
To Be Published
1ZA1
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Structure of wild-type E. coli Aspartate Transcarbamoylase in the presence of CTP at 2.20 A resolution
分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ...
著者Wang, J, Stieglitz, K.A, Cardia, J.P, Kantrowitz, E.R.
登録日2005-04-05
公開日2005-06-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for ordered substrate binding and cooperativity in aspartate transcarbamoylase
Proc.Natl.Acad.Sci.Usa, 102, 2005
6PNZ
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The structure of the Aspartate Transcarbamoylase trimer from Staphylococcus aureus complexed with PALA at 2.27 Resolution.
分子名称: Aspartate carbamoyltransferase, N-(PHOSPHONACETYL)-L-ASPARTIC ACID
著者Edwards, B.F.P, Evans, D.R, Patel, C.
登録日2019-07-03
公開日2020-07-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献The structure of the Aspartate Transcarbamoylase trimer from Staphylococcus aureus complexed with PALA at 2.27 Resolution.
To Be Published
9ATC
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ATCASE Y165F MUTANT
分子名称: ASPARTATE TRANSCARBAMOYLASE, ZINC ION
著者Ha, Y, Allewell, N.M.
登録日1998-06-26
公開日1999-07-26
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Intersubunit hydrogen bond acts as a global molecular switch in Escherichia coli aspartate transcarbamoylase.
Proteins, 33, 1998
7AT1
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CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ...
著者Gouaux, J.E, Stevens, R.C, Lipscomb, W.N.
登録日1989-09-22
公開日1990-10-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
6FBA
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Crystal Structure of truncated aspartate transcarbamoylase from Plasmodium falciparum with bound inhibitor 2,3-naphthalenediol
分子名称: Aspartate transcarbamoylase, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
著者Lunev, S, Bosch, S.S, Batista, F.A, Wang, C, Wrenger, C, Groves, M.R.
登録日2017-12-18
公開日2018-02-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase.
Biochem. Biophys. Res. Commun., 497, 2018
7K46
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Crystal Structure of a putative aspartate carbamoyltransferase Leishmania major Friedlin
分子名称: 1,2-ETHANEDIOL, Aspartate carbamoyltransferase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-09-14
公開日2020-09-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of a putative aspartate carbamoyltransferase Leishmania major Friedlin
to be published
7TMD
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Crystal structure of Ornithine carbamoyltransferase from Klebsiella pneumoniae
分子名称: BROMIDE ION, IODIDE ION, Ornithine carbamoyltransferase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-01-19
公開日2022-02-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of Ornithine carbamoyltransferase from Klebsiella pneumoniae
To be published
5AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
分子名称: ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
著者Stevens, R.C, Gouaux, J.E, Lipscomb, W.N.
登録日1990-04-26
公開日1990-10-15
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
6AT1
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STRUCTURAL CONSEQUENCES OF EFFECTOR BINDING TO THE T STATE OF ASPARTATE CARBAMOYLTRANSFERASE. CRYSTAL STRUCTURES OF THE UNLIGATED AND ATP-, AND CTP-COMPLEXED ENZYMES AT 2.6-ANGSTROMS RESOLUTION
分子名称: ASPARTATE CARBAMOYLTRANSFERASE (T STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
著者Stevens, R.C, Gouaux, J.E, Lipscomb, W.N.
登録日1990-04-26
公開日1990-10-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural consequences of effector binding to the T state of aspartate carbamoyltransferase: crystal structures of the unligated and ATP- and CTP-complexed enzymes at 2.6-A resolution.
Biochemistry, 29, 1990
7X99
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Anabolic ornithine carbamoyltransferases (OTCs) from Psychrobacter sp. PAMC 21119
分子名称: ornithine carbamoyltransferase
著者Do, H, Lee, J.H.
登録日2022-03-15
公開日2022-08-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Comparative structural insight into the unidirectional catalysis of ornithine carbamoyltransferases from Psychrobacter sp. PAMC 21119.
Plos One, 17, 2022
5VMQ
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STRUCTURE OF THE R105A MUTANT CATALYTIC TRIMER OF ESCHERICHIA COLI ASPARTATE TRANSCARBAMOYLASE AT 2.0-A RESOLUTION
分子名称: Aspartate carbamoyltransferase, CALCIUM ION, CHLORIDE ION
著者Beernink, P.T, Endrizzi, J.A.
登録日2017-04-28
公開日2017-05-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.012 Å)
主引用文献Charge neutralization in the active site of the catalytic trimer of aspartate transcarbamoylase promotes diverse structural changes.
Protein Sci., 26, 2017
2P2G
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Crystal Structure of Ornithine Carbamoyltransferase from Mycobacterium Tuberculosis (Rv1656): Orthorhombic Form
分子名称: Ornithine carbamoyltransferase, SULFATE ION
著者Sankaranarayanan, R, Cherney, M.M, Cherney, L.T, Garen, C, Moradian, F, James, M.N.G, TB Structural Genomics Consortium (TBSGC)
登録日2007-03-07
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structures of ornithine carbamoyltransferase from Mycobacterium tuberculosis and its ternary complex with carbamoyl phosphate and L-norvaline reveal the enzyme's catalytic mechanism.
J.Mol.Biol., 375, 2008
8BPL
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Aspartate transcarbamoylase mutant (N2045C, R2238C) from Chaetomium thermophilum CAD-like bound to carbamoyl phosphate
分子名称: Carbamoyl-phosphate synthase (glutamine-hydrolyzing), GLYCEROL, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ...
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2022-11-16
公開日2023-02-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD.
Molecules, 28, 2023
2OTC
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ORNITHINE TRANSCARBAMOYLASE COMPLEXED WITH N-(PHOSPHONACETYL)-L-ORNITHINE
分子名称: N-(PHOSPHONOACETYL)-L-ORNITHINE, ORNITHINE CARBAMOYLTRANSFERASE
著者Ha, Y, Allewell, N.M.
登録日1997-06-15
公開日1998-06-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Substrate-induced conformational change in a trimeric ornithine transcarbamoylase.
Proc.Natl.Acad.Sci.USA, 94, 1997
8BPS
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Aspartate transcarbamoylase mutant (N2045C, R2238C) from Chaetomium thermophilum CAD-like in apo form
分子名称: Carbamoyl-phosphate synthase (glutamine-hydrolyzing), GLYCEROL
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2022-11-25
公開日2023-02-01
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD.
Molecules, 28, 2023
4OH7
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Crystal structure of Ornithine carbamoyltransferase from Brucella melitensis
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Ornithine carbamoyltransferase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2014-01-17
公開日2014-02-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of Ornithine carbamoyltransferase from Brucella melitensis
To be Published
8QEV
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Crystal structure of ornithine transcarbamylase from Arabidopsis thaliana (AtOTC) in complex with carbamoyl phosphate
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ornithine transcarbamylase, ...
著者Nielipinski, M, Pietrzyk-Brzezinska, A, Sekula, B.
登録日2023-09-01
公開日2023-12-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural analysis and molecular substrate recognition properties of Arabidopsis thaliana ornithine transcarbamylase, the molecular target of phaseolotoxin produced by Pseudomonas syringae .
Front Plant Sci, 14, 2023
3GRF
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X-ray Structure of Ornithine Transcarbamoylase from Giardia lamblia
分子名称: NICKEL (II) ION, Ornithine carbamoyltransferase
著者Galkin, A, Herzberg, O.
登録日2009-03-25
公開日2009-06-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structure and kinetic properties of ornithine transcarbamoylase from the human parasite Giardia lamblia.
Proteins, 76, 2009
8QEU
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Crystal structure of ornithine transcarbamylase from Arabidopsis thaliana (AtOTC) in complex with ornithine
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, L-ornithine, ...
著者Nielipinski, M, Pietrzyk-Brzezinska, A, Sekula, B.
登録日2023-09-01
公開日2023-12-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural analysis and molecular substrate recognition properties of Arabidopsis thaliana ornithine transcarbamylase, the molecular target of phaseolotoxin produced by Pseudomonas syringae .
Front Plant Sci, 14, 2023
4NF2
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Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline
分子名称: CHLORIDE ION, NORVALINE, Ornithine carbamoyltransferase, ...
著者Shabalin, I.G, Handing, K, Cymborowski, M.T, Stam, J, Winsor, J, Shuvalova, L, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-10-30
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis
To be Published
1JS1
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Crystal Structure of a new transcarbamylase from the anaerobic bacterium Bacteroides fragilis at 2.0 A resolution
分子名称: PHOSPHATE ION, Transcarbamylase
著者Shi, D, Gallegos, R, DePonte III, J, Morizono, H, Yu, X, Allewell, N.M, Malamy, M, Tuchman, M.
登録日2001-08-15
公開日2002-07-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a transcarbamylase-like protein from the anaerobic bacterium Bacteroides fragilis at 2.0 A resolution.
J.Mol.Biol., 320, 2002

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