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PDB: 118 件
9DJ9
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HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) in distinct apo form
分子名称: Dual specificity protein phosphatase 3
著者Keedy, D.A, Lemberikman, A.M, Isiorho, E.A, Aleshin, A.E, Wu, J, Lambert, L.J, Cosford, N.D.P, Tautz, L.
登録日2024-09-06
公開日2024-09-25
実験手法X-RAY DIFFRACTION (1.924 Å)
主引用文献Fragment Screening Platform and Discovery of Novel Fragment Binders of the VHR Phosphatase, a Drug Target for Sepsis and Septic Shock
To Be Published
2Q05
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Crystal structure of tyr/ser protein phosphatase from Vaccinia virus WR
分子名称: Dual specificity protein phosphatase
著者Osipiuk, J, Skarina, T, Kagan, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2007-05-18
公開日2007-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Crystal structure of tyr/ser protein phosphatase from Vaccinia virus WR.
To be Published
5GTJ
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BU of 5gtj by Molmil
CRYSTAL STRUCTURE OF CATALYTICALLY ACTIVE FORM OF HUMAN DUSP26
分子名称: Dual specificity protein phosphatase 26, PHOSPHATE ION
著者Won, E.-Y, Kim, S.J, Chi, S.-W.
登録日2016-08-21
公開日2016-09-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insight into the Critical Role of the N-Terminal Region in the Catalytic Activity of Dual-Specificity Phosphatase 26
Plos One, 11, 2016
7NCY
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Dual specificity phosphatase from Sulfolobales Beppu filamentous virus 3
分子名称: Dual specificity phosphatase, GLYCEROL, NICKEL (II) ION
著者Welin, M, Akutsu, M, Hakansson, M, Al-Karadaghi, S, Jasilionis, A, Nordberg Karlsson, E.
登録日2021-01-29
公開日2022-03-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dual specificity phosphatase from Sulfolobales Beppu filamentous virus 3
To Be Published
4HRF
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Atomic structure of DUSP26
分子名称: Dual specificity protein phosphatase 26
著者Lokareddy, R.K, Bhardwaj, A, Cingolani, G.
登録日2012-10-27
公開日2013-01-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Atomic structure of dual-specificity phosphatase 26, a novel p53 phosphatase.
Biochemistry, 52, 2013
2Y96
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Structure of human dual-specificity phosphatase 27
分子名称: DUAL SPECIFICITY PHOSPHATASE DUPD1, SULFATE ION
著者Lountos, G.T, Tropea, J.E, Waugh, D.S.
登録日2011-02-11
公開日2011-04-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structure of Human Dual-Specificity Phosphatase at 2.38A Resolution
Acta Crystallogr.,Sect.D, 67, 2011
4R30
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Structure of human laforin dual specificity phosphatase domain
分子名称: BETA-MERCAPTOETHANOL, Laforin, SULFATE ION
著者Sankhala, R.S, Koksal, A.C, Cingolani, G.
登録日2014-08-13
公開日2014-12-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Dimeric quaternary structure of human laforin.
J.Biol.Chem., 290, 2015
6LMY
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Crystal structure of DUSP22 mutant_C88S/S93A
分子名称: Dual specificity protein phosphatase 22, PHOSPHATE ION
著者Lai, C.H, Lyu, P.C.
登録日2019-12-27
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases.
Int J Mol Sci, 21, 2020
6LOT
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Crystal structure of DUSP22 mutant_N128D
分子名称: Dual specificity protein phosphatase 22, SULFATE ION
著者Lai, C.H, Lyu, P.C.
登録日2020-01-07
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases.
Int J Mol Sci, 21, 2020
3LJ8
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Crystal Structure of MKP-4
分子名称: Tyrosine-protein phosphatase
著者Jeong, D.G, Yoon, T.S, Jung, S.-K, Park, H.S, Ryu, S.E, Kim, S.J.
登録日2010-01-26
公開日2010-12-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Exploring binding sites other than the catalytic core in the crystal structure of the catalytic domain of MKP-4
Acta Crystallogr.,Sect.D, 67, 2011
4WOH
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Structure of of human dual-specificity phosphatase 22 (E24A/K28A/K30A/C88S) complexed with 4-nitrophenolphosphate
分子名称: 1,2-ETHANEDIOL, 4-NITROPHENYL PHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
著者Lountos, G.T, Cherry, S, Tropea, J.E, Waugh, D.S.
登録日2014-10-15
公開日2015-02-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Structural analysis of human dual-specificity phosphatase 22 complexed with a phosphotyrosine-like substrate.
Acta Crystallogr.,Sect.F, 71, 2015
5NCR
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OH1 from the Orf virus: a tyrosine phosphatase that displays distinct structural features and triple substrate specificity
分子名称: PHOSPHATE ION, SULFATE ION, tyrosine phosphatase
著者Segovia, D, Haouz, A, Berois, M, Villarino, A, Andre-Leroux, G.
登録日2017-03-06
公開日2017-08-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity.
J. Mol. Biol., 429, 2017
5M43
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Crystal structure of Yvh1 phosphatase domain from Chaetomium thermophilum
分子名称: GLYCEROL, NITRATE ION, Putative uncharacterized protein
著者Ahmed, Y.L, Sinning, I.
登録日2016-10-18
公開日2016-11-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.646 Å)
主引用文献Interaction network of the ribosome assembly machinery from a eukaryotic thermophile.
Protein Sci., 26, 2017
4Y2E
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Crystal structure of the catalytic domain of human dual-specificity phosphatase 7 (C232S)
分子名称: Dual specificity protein phosphatase 7, PHOSPHATE ION
著者Lountos, G.T, Austin, B.P, Tropea, J.E, Waugh, D.S.
登録日2015-02-09
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structure of human dual-specificity phosphatase 7, a potential cancer drug target.
Acta Crystallogr.,Sect.F, 71, 2015
1MKP
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CRYSTAL STRUCTURE OF PYST1 (MKP3)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, PYST1
著者Stewart, A.E, Dowd, S, Keyse, S, Mcdonald, N.Q.
登録日1998-07-11
公開日1999-07-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation.
Nat.Struct.Biol., 6, 1999
7EZN
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Crystal structure of CnYvh1 complex with vanadate
分子名称: 1,2-ETHANEDIOL, Protein-tyrosine-phosphatase, VANADATE ION
著者Choi, M.K, Yoo, Y.
登録日2021-06-01
公開日2022-06-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of CnYvh1 complex with vanadate
To Be Published
6I28
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Crystal Structure of Cydia Pomonella PTP-2 phosphatase
分子名称: CALCIUM ION, GLYCEROL, ORF98 PTP-2
著者Huang, G, Keown, J.P, Oliver, M.R, Metcalf, P.
登録日2018-10-31
公開日2019-02-20
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of protein tyrosine phosphatase-2 from Cydia pomonella granulovirus.
Acta Crystallogr.,Sect.F, 75, 2019
4NYH
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Orthorhombic crystal form of pir1 dual specificity phosphatase core
分子名称: CHLORIDE ION, PHOSPHATE ION, RNA/RNP complex-1-interacting phosphatase
著者Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
登録日2013-12-10
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of Human PIR1, an Atypical Dual-Specificity Phosphatase.
Biochemistry, 53, 2014
7C8S
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Crystal structure of DUSP22 mutant_N128A
分子名称: Dual specificity protein phosphatase 22, SULFATE ION
著者Lai, C.H, Lyu, P.C.
登録日2020-06-03
公開日2020-10-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases.
Int J Mol Sci, 21, 2020
6L1S
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Crystal structure of DUSP22 mutant_C88S
分子名称: Dual specificity protein phosphatase 22, PHOSPHATE ION
著者Lai, C.H, Chang, C.C, Lyu, P.C.
登録日2019-09-30
公開日2020-10-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.3611 Å)
主引用文献Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases.
Int J Mol Sci, 21, 2020
1M3G
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BU of 1m3g by Molmil
SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF MAPK PHOSPHATASE PAC-1: INSIGHTS INTO SUBSTRATE-INDUCED ENZYMATIC ACTIVATION
分子名称: DUAL SPECIFICITY PROTEIN PHOSPHATASE 2
著者Farooq, A, Zhou, M.-M.
登録日2002-06-27
公開日2003-06-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of the MAPK Phosphatase PAC-1 Catalytic Domain Insights into Substrate-Induced Enzymatic Activation of MKP
Structure, 11, 2003
2R0B
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Crystal structure of human tyrosine phosphatase-like serine/threonine/tyrosine-interacting protein
分子名称: GLYCEROL, SULFATE ION, Serine/threonine/tyrosine-interacting protein
著者Bonanno, J.B, Freeman, J, Bain, K.T, Iizuka, M, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-08-18
公開日2007-08-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural genomics of protein phosphatases.
J.Struct.Funct.Genom., 8, 2007
1I9S
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CRYSTAL STRUCTURE OF THE RNA TRIPHOSPHATASE DOMAIN OF MOUSE MRNA CAPPING ENZYME
分子名称: CACODYLATE ION, ISOPROPYL ALCOHOL, MAGNESIUM ION, ...
著者Changela, A, Ho, C.K, Martins, A, Shuman, S, Mondragon, A.
登録日2001-03-20
公開日2001-05-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure and mechanism of the RNA triphosphatase component of mammalian mRNA capping enzyme.
EMBO J., 20, 2001
2RF6
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Crystal Structure of the Vaccinia Virus Dual-Specificity Phosphatase VH1
分子名称: Dual specificity protein phosphatase, SULFATE ION
著者Koksal, A.C, Cingolani, G.
登録日2007-09-28
公開日2008-09-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of the Vaccinia Virus Dual-Specificity Phosphatase VH1
To be Published
1J4X
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HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE C124S MUTANT-PEPTIDE COMPLEX
分子名称: DDE(AHP)(TPO)G(PTR)VATR, DUAL SPECIFICITY PROTEIN PHOSPHATASE 3
著者Schumacher, M.A, Todd, J.L, Tanner, K.G, Denu, J.M.
登録日2001-12-13
公開日2001-12-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase.
Biochemistry, 41, 2002

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