9DJ9

HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) in distinct apo form

Summary for 9DJ9

• Entry DOI: 10.2210/pdb9dj9/pdb
• Related: 8TK2 8TK3 8TK4 8TK5 8TK6
• Descriptor: Dual specificity protein phosphatase 3 (2 entities in total)
• Functional Keywords: phosphatase, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 20984.73

Authors

Keedy, D.A.,Lemberikman, A.M.,Isiorho, E.A.,Aleshin, A.E.,Wu, J.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L. (deposition date: 2024-09-06, release date: 2024-09-25)

• Primary citation: Wu, J.,Baranowski, M.R.,Aleshin, A.E.,Lambert, L.J.,Isiorho, E.A.,Lemberikman, A.M.,Keedy, D.A.,Cosford, N.D.P.,Tautz, L.; Fragment Screening Platform and Discovery of Novel Fragment Binders of the VHR Phosphatase, a Drug Target for Sepsis and Septic Shock; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.924 Å)