8TK3

HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) having oxidized catalytic cysteine and complexed with 6-(difluoromethyl)pyrimidin-4-ol at two allosteric sites

Summary for 8TK3

• Entry DOI: 10.2210/pdb8tk3/pdb
• Descriptor: Dual specificity protein phosphatase 3, 6-(difluoromethyl)pyrimidin-4-ol, DIMETHYL SULFOXIDE, ... (4 entities in total)
• Functional Keywords: protein dual-specificity phosphatase, vhr, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 20841.59

Authors

Aleshin, A.E.,Wu, J.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L. (deposition date: 2023-07-25, release date: 2024-08-14)

• Primary citation: Aleshin, A.E.,Wu, J.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L.; HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) having oxidized catalytic cysteine and complexed with 6-(difluoromethyl)pyrimidin-4-ol at two allosteric sites; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)