8TK3
HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) having oxidized catalytic cysteine and complexed with 6-(difluoromethyl)pyrimidin-4-ol at two allosteric sites
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity protein phosphatase 3 | polymer | 183 | 20315.0 | 1 | UniProt (P51452) Pfam (PF00782) | Homo sapiens (human) | Dual specificity protein phosphatase VHR,Vaccinia H1-related phosphatase,VHR |
| 2 | B, C (A) | 6-(difluoromethyl)pyrimidin-4-ol | non-polymer | 146.1 | 2 | Chemie (I2X) | |||
| 3 | D, E, F (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 4 | G (A) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20315.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 526.6 | |
| All* | Total formula weight | 20841.6 |
