7NY1
 
 | | Structure of the fungal plasma membrane proton pump Pma1 in its auto-inhibited state - hexameric assembly | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, POTASSIUM ION, ... | | 著者 | Heit, S, Geurts, M.M.G, Murphy, B.J, Corey, R, Mills, D.J, Kuehlbrandt, W, Bublitz, M. | | 登録日 | 2021-03-19 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Structure of the hexameric fungal plasma membrane proton pump in its autoinhibited state.
Sci Adv, 7, 2021
|
|
3NAL
 | | SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative DTB | | 分子名称: | (3S,3aR,4S,6S,6aS,8R,9bS)-6-(acetyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-4-yl dodecanoate, MAGNESIUM ION, POTASSIUM ION, ... | | 著者 | Winther, A.M.L, Sonntag, Y, Olesen, C, Moller, J.V, Nissen, P. | | 登録日 | 2010-06-02 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs
J.Biol.Chem., 285, 2010
|
|
3NAM
 | | SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative dOTg | | 分子名称: | (3S,3aR,4S,6S,6aS,8R,9R,9aR,9bS)-6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-2-oxododecahydroazuleno[4,5-b]furan-8-yl (2Z)-2-methylbut-2-enoate, MAGNESIUM ION, PHOSPHATIDYLETHANOLAMINE, ... | | 著者 | Winther, A.M.L, Sonntag, Y, Olesen, C, Moller, J.V, Nissen, P. | | 登録日 | 2010-06-02 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs
J.Biol.Chem., 285, 2010
|
|
4YCN
 | | Crystal structure of the calcium pump with bound marine macrolide BLLB | | 分子名称: | (4S,5E,8S,9E,11S,13E,15E,18R)-4-hydroxy-8-methoxy-9,11-dimethyl-18-[(1Z,4E)-2-methylhexa-1,4-dien-1-yl]oxacyclooctadeca-5,9,13,15-tetraen-2-one, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ... | | 著者 | Morita, M, Ogawa, H, Ohno, O, Yamori, T, Suenaga, K, Toyoshima, C. | | 登録日 | 2015-02-20 | | 公開日 | 2016-01-13 | | 最終更新日 | 2020-02-05 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Biselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca(2+) pumps with a unique mode of binding
Febs Lett., 589, 2015
|
|
3W5C
 | | Crystal structure of the calcium pump in the E2 state free from exogenous inhibitors | | 分子名称: | PHOSPHATIDYLETHANOLAMINE, SERCA1a, SODIUM ION | | 著者 | Toyoshima, C, Iwasawa, S, Ogawa, H, Hirata, A, Tsueda, J, Inesi, G. | | 登録日 | 2013-01-27 | | 公開日 | 2013-03-06 | | 最終更新日 | 2013-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of the calcium pump and sarcolipin in the Mg2+-bound E1 state.
Nature, 495, 2013
|
|
3WGV
 | | Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state with oligomycin | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Kanai, R, Ogawa, H, Vilsen, B, Cornelius, F, Toyoshima, C. | | 登録日 | 2013-08-09 | | 公開日 | 2013-10-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of a Na1-bound Na1,K1-ATPase preceding the E1P state
Nature, 502, 2013
|
|
7OP1
 | |
7OP3
 | | Cryo-EM structure of P5B-ATPase E2PiSPM | | 分子名称: | Cation-transporting ATPase, SPERMINE | | 著者 | Li, P, Gronberg, C, Wang, K.T, Salustros, N, Gourdon, P.E. | | 登録日 | 2021-05-28 | | 公開日 | 2021-06-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
|
|
7OP8
 | |
7OP5
 | | Cryo-EM structure of P5B-ATPase E2P | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, P5B-ATPase | | 著者 | Li, P, Gourdon, P. | | 登録日 | 2021-05-29 | | 公開日 | 2021-06-30 | | 最終更新日 | 2021-09-01 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structure and transport mechanism of P5B-ATPases.
Nat Commun, 12, 2021
|
|
4YCM
 | | Crystal structure of the calcium pump with bound marine macrolide BLS | | 分子名称: | (4S,5E,8S,9E,11S,13E,15E,18R)-8-methoxy-9,11-dimethyl-18-[(1Z,4E)-2-methylhexa-1,4-dien-1-yl]-2-oxooxacyclooctadeca-5,9,13,15-tetraen-4-yl 3-O-methyl-beta-D-glucopyranoside, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ... | | 著者 | Morita, M, Ogawa, H, Ohno, O, Yamori, T, Suenaga, K, Toyoshima, C. | | 登録日 | 2015-02-20 | | 公開日 | 2016-01-13 | | 最終更新日 | 2020-02-05 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Biselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca(2+) pumps with a unique mode of binding
Febs Lett., 589, 2015
|
|
3N5K
 | | Structure Of The (Sr)Ca2+-ATPase E2-AlF4- Form | | 分子名称: | ACETATE ION, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ... | | 著者 | Bublitz, M, Olesen, C, Poulsen, H, Morth, J.P, Moller, J.V, Nissen, P. | | 登録日 | 2010-05-25 | | 公開日 | 2011-06-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Ion pathways in the sarcoplasmic reticulum Ca2+-ATPase.
J.Biol.Chem., 288, 2013
|
|
3N23
 | | Crystal structure of the high affinity complex between ouabain and the E2P form of the sodium-potassium pump | | 分子名称: | MAGNESIUM ION, Na+/K+ ATPase gamma subunit transcript variant a, OUABAIN, ... | | 著者 | Yatime, L, Laursen, M, Morth, J.P, Esmann, M, Nissen, P, Fedosova, N.U. | | 登録日 | 2010-05-17 | | 公開日 | 2011-01-19 | | 最終更新日 | 2014-09-17 | | 実験手法 | X-RAY DIFFRACTION (4.6 Å) | | 主引用文献 | Structural insights into the high affinity binding of cardiotonic steroids to the Na+,K+-ATPase.
J.Struct.Biol., 174, 2011
|
|
3WGU
 | | Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state without oligomycin | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Kanai, R, Ogawa, H, Vilsen, B, Cornelius, F, Toyoshima, C. | | 登録日 | 2013-08-09 | | 公開日 | 2013-10-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of a Na1-bound Na1,K1-ATPase preceding the E1P state
Nature, 502, 2013
|
|
7Y45
 | | Cryo-EM structure of the Na+,K+-ATPase in the E2.2K+ state | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-06-14 | | 公開日 | 2022-07-13 | | 最終更新日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-electron microscopy of Na + ,K + -ATPase reveals how the extracellular gate locks in the E2·2K + state.
Febs Lett., 596, 2022
|
|
7Y46
 | | Cryo-EM structure of the Na+,K+-ATPase in the E2.2K+ state after addition of ATP | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-06-14 | | 公開日 | 2022-07-13 | | 最終更新日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | | 主引用文献 | Cryo-electron microscopy of Na + ,K + -ATPase reveals how the extracellular gate locks in the E2·2K + state.
Febs Lett., 596, 2022
|
|
7YAG
 | | CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 1 | | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Chen, Z, Watanabe, S, Inaba, K. | | 登録日 | 2022-06-28 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
|
|
7YAH
 | | CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 2 | | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Chen, Z, Watanabe, S, Inaba, K. | | 登録日 | 2022-06-28 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
|
|
7YAI
 | | CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 3 | | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, Nanobody head piece of megabody, ... | | 著者 | Chen, Z, Watanabe, S, Inaba, K. | | 登録日 | 2022-06-28 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
|
|
7YAM
 | | CryoEM structure of SPCA1a in E2P state | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION | | 著者 | Chen, Z, Watanabe, S, Inaba, K. | | 登録日 | 2022-06-28 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
|
|
7YAJ
 | | CryoEM structure of SPCA1a in E1-Mn-AMPPCP state subclass 1 | | 分子名称: | Calcium-transporting ATPase type 2C member 1, MANGANESE (II) ION, Nanobody head piece of megabody, ... | | 著者 | Chen, Z, Watanabe, S, Inaba, K. | | 登録日 | 2022-06-28 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
|
|
6LN5
 | | CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class1) | | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
|
|
6LN9
 | | CryoEM structure of SERCA2b T1032stop in E2-BeF3- state (class2) | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2020-09-16 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
|
|
6LN7
 | | CryoEM structure of SERCA2b T1032stop in E1-2Ca2+-AMPPCP (class3) | | 分子名称: | CALCIUM ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
|
|
6LN8
 | | CryoEM structure of SERCA2b T1032stop in E2-BeF3- state (class1) | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | | 著者 | Zhang, Y, Tsutsumi, A, Watanabe, S, Inaba, K. | | 登録日 | 2019-12-28 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structures of SERCA2b reveal the mechanism of regulation by the luminal extension tail.
Sci Adv, 6, 2020
|
|
