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PDB: 392 件

3WMF
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Crystal structure of an inward-facing eukaryotic ABC multitrug transporter G277V/A278V/A279V mutant
分子名称: ATP-binding cassette, sub-family B, member 1, ...
著者Kodan, A, Yamaguchi, T, Nakatsu, T, Kato, H.
登録日2013-11-18
公開日2014-03-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for gating mechanisms of a eukaryotic P-glycoprotein homolog.
Proc.Natl.Acad.Sci.USA, 111, 2014
5C76
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BU of 5c76 by Molmil
ATP-driven lipid-linked oligosaccharide flippase PglK in apo-inward facing state (2)
分子名称: WlaB protein
著者Perez, C, Gerber, S, Locher, K.P.
登録日2015-06-24
公開日2015-08-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.94 Å)
主引用文献Structure and mechanism of an active lipid-linked oligosaccharide flippase.
Nature, 524, 2015
4LSG
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BU of 4lsg by Molmil
Structure of Mouse P-Glycoprotein
分子名称: MERCURY (II) ION, Multidrug resistance protein 1A
著者Chang, G, Szewczyk, P.
登録日2013-07-22
公開日2013-07-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献

4M2T
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BU of 4m2t by Molmil
Corrected Structure of Mouse P-glycoprotein bound to QZ59-SSS
分子名称: (4S,11S,18S)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, Multidrug resistance protein 1A
著者Li, J, Jaimes, K.F, Aller, S.G.
登録日2013-08-05
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.35 Å)
主引用文献Refined structures of mouse P-glycoprotein.
Protein Sci., 23, 2014
5C73
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BU of 5c73 by Molmil
ATP-driven lipid-linked oligosaccharide flippase PglK in outward-occluded conformation
分子名称: Protein glycosylation K
著者Perez, C, Locher, K.P.
登録日2015-06-24
公開日2015-08-19
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (5.9 Å)
主引用文献Structure and mechanism of an active lipid-linked oligosaccharide flippase.
Nature, 524, 2015
4MRN
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BU of 4mrn by Molmil
Structure of a bacterial Atm1-family ABC transporter
分子名称: ABC transporter related protein, LAURYL DIMETHYLAMINE-N-OXIDE, PHOSPHATE ION
著者Lee, J.Y, Yang, J.G, Zhitnitsky, D, Lewinson, O, Rees, D.C.
登録日2013-09-17
公開日2014-03-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for heavy metal detoxification by an Atm1-type ABC exporter.
Science, 343, 2014
8HF5
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BU of 8hf5 by Molmil
Cryo-EM structure of nucleotide-bound ComA at outward-facing state with EC gate open conformation
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transport/processing ATP-binding protein ComA
著者Yu, L, Xin, X, Min, L.
登録日2022-11-09
公開日2023-10-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
8HF6
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BU of 8hf6 by Molmil
Cryo-EM structure of nucleotide-bound ComA E647Q mutant
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Competence factor transporting ATP-binding protein/permease ComA
著者Yu, L, Xin, X, Min, L.
登録日2022-11-09
公開日2023-10-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
8HF4
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BU of 8hf4 by Molmil
Cryo-EM structure of nucleotide-bound ComA at outward-facing state with EC gate closed conformation
分子名称: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transport/processing ATP-binding protein ComA
著者Yu, L, Xin, X, Min, L.
登録日2022-11-09
公開日2023-10-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
4MRS
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BU of 4mrs by Molmil
Structure of a bacterial Atm1-family ABC transporter
分子名称: ABC transporter related protein, LAURYL DIMETHYLAMINE-N-OXIDE, OXIDIZED GLUTATHIONE DISULFIDE, ...
著者Lee, J.Y, Yang, J.G, Zhitnitsky, D, Lewinson, O, Rees, D.C.
登録日2013-09-17
公開日2014-03-19
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for heavy metal detoxification by an Atm1-type ABC exporter.
Science, 343, 2014
5C78
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BU of 5c78 by Molmil
ATP-driven lipid-linked oligosaccharide flippase PglK in apo-inward state (1)
分子名称: ATP-driven flippase PglK, PENTAETHYLENE GLYCOL
著者Perez, C, Locher, K.P.
登録日2015-06-24
公開日2015-08-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure and mechanism of an active lipid-linked oligosaccharide flippase.
Nature, 524, 2015
8HF7
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BU of 8hf7 by Molmil
Cryo-EM structure of ComA bound to its mature substrate CSP peptide
分子名称: Competence factor transporting ATP-binding protein/permease ComA, Competence-stimulating peptide type 1
著者Yu, L, Xin, X, Min, L.
登録日2022-11-09
公開日2023-10-11
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
6O2P
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BU of 6o2p by Molmil
Complex of ivacaftor with cystic fibrosis transmembrane conductance regulator (CFTR)
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ...
著者Liu, F, Zhang, Z, Chen, J, Levit, A, Shoichet, B.
登録日2019-02-24
公開日2019-06-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural identification of a hotspot on CFTR for potentiation.
Science, 364, 2019
6O1V
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BU of 6o1v by Molmil
Complex of human cystic fibrosis transmembrane conductance regulator (CFTR) and GLPG1837
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ...
著者Zhang, Z, Liu, F, Chen, J, Levit, A, Shoichet, B.
登録日2019-02-21
公開日2019-06-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural identification of a hotspot on CFTR for potentiation.
Science, 364, 2019
6O30
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BU of 6o30 by Molmil
Lipid A transporter MsbA from Salmonella typhimurium
分子名称: Lipid A export ATP-binding/permease protein MsbA
著者Padayatti, P.S, Zhang, Q, Wilson, I.A, Lee, S.C, Stanfield, R.L.
登録日2019-02-25
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.47 Å)
主引用文献Structural Insights into the Lipid A Transport Pathway in MsbA.
Structure, 27, 2019
6C3O
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BU of 6c3o by Molmil
Cryo-EM structure of human KATP bound to ATP and ADP in quatrefoil form
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Lee, K.P.K, Chen, J, MacKinnon, R.
登録日2018-01-10
公開日2018-01-31
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular structure of human KATP in complex with ATP and ADP
Elife, 6, 2017
6D3S
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BU of 6d3s by Molmil
Thermostabilized phosphorylated chicken CFTR
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator
著者Fay, J.F, Riordan, J.R, Chen, Z.J.
登録日2018-04-16
公開日2018-10-17
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Cryo-EM Visualization of an Active High Open Probability CFTR Anion Channel.
Biochemistry, 57, 2018
6C3P
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BU of 6c3p by Molmil
Cryo-EM structure of human KATP bound to ATP and ADP in propeller form
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ...
著者Lee, K.P.K, Chen, J, MacKinnon, R.
登録日2018-01-10
公開日2018-01-24
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Molecular structure of human KATP in complex with ATP and ADP.
Elife, 6, 2017
6C0V
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BU of 6c0v by Molmil
Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance protein 1
著者Kim, Y.J, Chen, J.
登録日2018-01-02
公開日2018-01-31
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation.
Science, 359, 2018
5EG1
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BU of 5eg1 by Molmil
Antibacterial peptide ABC transporter McjD with a resolved lipid
分子名称: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, MAGNESIUM ION, Microcin-J25 export ATP-binding/permease protein McjD, ...
著者Choudhury, H.G, Beis, K.
登録日2015-10-26
公開日2016-08-31
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Structural and Functional Basis for Lipid Synergy on the Activity of the Antibacterial Peptide ABC Transporter McjD.
J.Biol.Chem., 291, 2016
6PAM
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BU of 6pam by Molmil
Structure of a bacterial Atm1-family ABC transporter with MgADP bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATM1-type heavy metal exporter, MAGNESIUM ION
著者Fan, C, Kaiser, J.T, Rees, D.C.
登録日2019-06-11
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6JB3
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BU of 6jb3 by Molmil
Structure of SUR1 subunit bound with repaglinide
分子名称: ATP-binding cassette sub-family C member 8 isoform X2, Digitonin, Repaglinide
著者Chen, L, Ding, D, Wang, M, Wu, J.-X, Kang, Y.
登録日2019-01-25
公開日2019-05-22
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel.
Cell Rep, 27, 2019
6LR0
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BU of 6lr0 by Molmil
structure of human bile salt exporter ABCB11
分子名称: Bile salt export pump
著者Wang, L, Hou, W.T, Chen, L, Jiang, Y.L, Xu, D, Sun, L.F, Zhou, C.Z, Chen, Y.
登録日2020-01-15
公開日2020-04-15
最終更新日2023-01-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of human bile salts exporter ABCB11.
Cell Res., 30, 2020
6JB1
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Structure of pancreatic ATP-sensitive potassium channel bound with repaglinide and ATPgammaS at 3.3A resolution
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ATP-binding cassette sub-family C member 8 isoform X2, ATP-sensitive inward rectifier potassium channel 11, ...
著者Chen, L, Ding, D, Wang, M, Wu, J.-X, Kang, Y.
登録日2019-01-25
公開日2019-05-22
最終更新日2021-09-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The Structural Basis for the Binding of Repaglinide to the Pancreatic KATPChannel.
Cell Rep, 27, 2019
6MSM
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Phosphorylated, ATP-bound human cystic fibrosis transmembrane conductance regulator (CFTR)
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ...
著者Zhang, Z, Liu, F, Chen, J.
登録日2018-10-16
公開日2018-11-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular structure of the ATP-bound, phosphorylated human CFTR.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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