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PDB: 660 件

7WEG
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Complex structure of PDZD7 and FCHSD2
分子名称: FCHSD2, PDZ domain-containing protein 7, ZINC ION
著者Wang, H, Lin, L, Lu, Q.
登録日2021-12-23
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Deafness-related protein PDZD7 forms complex with the C-terminal tail of FCHSD2.
Biochem.J., 479, 2022
7X2E
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Structure of USH1C PDZ2 and coiled-coil in complex with CDHR2 C-terminal tail
分子名称: Cadherin-related family member 2, GLYCEROL, Harmonin
著者Yan, W, Chen, G, Li, J.
登録日2022-02-25
公開日2022-07-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of the Harmonin PDZ2 and coiled-coil domains in a complex with CDHR2 tail and its implications.
Faseb J., 36, 2022
7XTY
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Crystal Structure of the second PDZ domain from human PTPN13 in complex with APC peptide
分子名称: APC-peptide, Tyrosine-protein phosphatase non-receptor type 13
著者Jing, L.Q, Sun, X.N, Ma, W.H, Zhou, W.J, Wu, D.L.
登録日2022-05-18
公開日2023-05-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Targeting PTPN13 with 11 amino acid peptides of C-terminal APC prevents immune evasion of colorectal cancer
to be published
6RQR
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Extended NHERF1 PDZ2 domain in complex with the PDZ-binding motif of CFTR
分子名称: Na(+)/H(+) exchange regulatory cofactor NHE-RF1,Cystic fibrosis transmembrane conductance regulator
著者Martin, E.R, Ford, R.C, Robinson, R.C.
登録日2019-05-16
公開日2020-02-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献In vivocrystals reveal critical features of the interaction between cystic fibrosis transmembrane conductance regulator (CFTR) and the PDZ2 domain of Na+/H+exchange cofactor NHERF1.
J.Biol.Chem., 295, 2020
6UBH
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Structure of the MM7 Erbin PDZ variant in complex with a high-affinity peptide
分子名称: Erbin, SODIUM ION, peptide
著者Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S.
登録日2019-09-11
公開日2020-07-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain.
J.Mol.Biol., 433, 2021
6IRE
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Complex structure of INAD PDZ45 and NORPA CC-PBM
分子名称: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase, Inactivation-no-after-potential D protein
著者Ye, F, Li, J, Deng, X, Liu, W, Zhang, M.
登録日2018-11-12
公開日2019-01-23
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献An unexpected INAD PDZ tandem-mediated plc beta binding in Drosophila photo receptors.
Elife, 7, 2018
6HKS
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Crystal structure of the PTPN3 PDZ domain bound to the HPV16 E6 oncoprotein C-terminal peptide
分子名称: IODIDE ION, Protein E6, Tyrosine-protein phosphatase non-receptor type 3
著者Genera, M, Haouz, A, Caillet-Saguy, C.
登録日2018-09-07
公開日2019-05-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1944108 Å)
主引用文献Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein.
Sci Rep, 9, 2019
6Q0N
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Structure of the Erbin PDB domain in complex with a high-affinity peptide
分子名称: Erbin, peptide
著者Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S.
登録日2019-08-02
公開日2019-11-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities.
Protein Sci., 29, 2020
6Q0U
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Structure of the Erbin PDZ variant E-6a with a high-affinity C-terminal peptide
分子名称: 1,2-ETHANEDIOL, Erbin, peptide
著者Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S.
登録日2019-08-02
公開日2019-11-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities.
Protein Sci., 29, 2020
6Q0M
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Structure of Erbin PDZ derivative E-14 with a high-affinity peptide
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
著者Singer, A.U, Teyra, J, Ernst, A, Sicheri, F, Sidhu, S.S.
登録日2019-08-02
公開日2019-11-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Comprehensive analysis of all evolutionary paths between two divergent PDZ domain specificities.
Protein Sci., 29, 2020
6QJJ
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Crystal Structure of the third PDZ domain of PSD-95 protein: space group P3221
分子名称: Disks large homolog 4, SULFATE ION
著者Camara-Artigas, A.
登録日2019-01-24
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Acta Crystallogr D Struct Biol, 75, 2019
6QJD
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Crystal Structure of the truncated form of the third PDZ domain of PSD-95: residues 302-392
分子名称: Disks large homolog 4, SULFATE ION
著者Camara-Artigas, A.
登録日2019-01-24
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.551 Å)
主引用文献Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Acta Crystallogr D Struct Biol, 75, 2019
6QJN
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Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group I4122
分子名称: Disks large homolog 4
著者Camara-Artigas, A.
登録日2019-01-24
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Acta Crystallogr D Struct Biol, 75, 2019
6QJI
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Crystal Structure of the third PDZ domain of PSD-95 protein: space group P3112
分子名称: Disks large homolog 4, SULFATE ION
著者Camara-Artigas, A.
登録日2019-01-24
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Acta Crystallogr D Struct Biol, 75, 2019
6QJF
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BU of 6qjf by Molmil
Crystal Structure of the third PDZ domain of PSD-95 protein D332P mutant: space group C121, structure 1
分子名称: Disks large homolog 4
著者Camara-Artigas, A.
登録日2019-01-24
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Acta Crystallogr D Struct Biol, 75, 2019
6QJL
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BU of 6qjl by Molmil
Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group P21
分子名称: Disks large homolog 4, GLYCEROL, SULFATE ION
著者Camara-Artigas, A.
登録日2019-01-24
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.043 Å)
主引用文献Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Acta Crystallogr D Struct Biol, 75, 2019
6QJG
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BU of 6qjg by Molmil
Crystal Structure of the third PDZ domain of PSD-95 protein D332P mutant: space group C121, structure 2
分子名称: Disks large homolog 4
著者Camara-Artigas, A.
登録日2019-01-24
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Acta Crystallogr D Struct Biol, 75, 2019
6QJK
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BU of 6qjk by Molmil
Crystal Structure of the third PDZ domain of PSD-95 protein D332G mutant: space group P43
分子名称: Disks large homolog 4, GLYCEROL, SULFATE ION
著者Camara-Artigas, A.
登録日2019-01-24
公開日2019-04-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.046 Å)
主引用文献Conformational changes in the third PDZ domain of the neuronal postsynaptic density protein 95.
Acta Crystallogr D Struct Biol, 75, 2019
6JUE
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The complex of PDZ and PBM
分子名称: Partitioning defective 3 homolog, SULFATE ION, THR-ILE-ILE-THR-LEU
著者Liu, Z.
登録日2019-04-13
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.549 Å)
主引用文献Par complex cluster formation mediated by phase separation.
Nat Commun, 11, 2020
6LCB
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BU of 6lcb by Molmil
Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009
分子名称: 2-[[3-[(2E)-2-[1,3-bis(oxidanylidene)-1-phenyl-butan-2-ylidene]hydrazinyl]phenyl]sulfonylamino]benzoic acid, SULFATE ION, Segment polarity protein dishevelled homolog DVL-1
著者Yasukochi, S, Numoto, N, Tenno, N, Tenno, T, Ito, N, Hiroaki, H.
登録日2019-11-18
公開日2020-11-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of human Dishevelled1 PDZ domain with its inhibitor NPL3009
To Be Published
1I92
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BU of 1i92 by Molmil
STRUCTURAL BASIS OF THE NHERF PDZ1-CFTR INTERACTION
分子名称: CHLORIDE ION, NA+/H+ EXCHANGE REGULATORY CO-FACTOR
著者Karthikeyan, S, Leung, T, Ladias, J.A.A.
登録日2001-03-16
公開日2001-06-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of the Na+/H+ exchanger regulatory factor PDZ1 interaction with the carboxyl-terminal region of the cystic fibrosis transmembrane conductance regulator.
J.Biol.Chem., 276, 2001
1IU2
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The first PDZ domain of PSD-95
分子名称: PSD-95
著者Long, J.-F, Tochio, H, Wang, P, Sala, C, Niethammer, M, Sheng, M, Zhang, M.
登録日2002-02-19
公開日2003-03-11
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95
J.MOL.BIOL., 327, 2003
1KWA
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HUMAN CASK/LIN-2 PDZ DOMAIN
分子名称: HCASK/LIN-2 PROTEIN, SULFATE ION
著者Daniels, D.L, Cohen, A.R, Anderson, J.M, Brunger, A.T.
登録日1998-01-16
公開日1998-05-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structure of the hCASK PDZ domain reveals the structural basis of class II PDZ domain target recognition
Nat.Struct.Biol., 5, 1998
1L6O
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XENOPUS DISHEVELLED PDZ DOMAIN
分子名称: Dapper 1, Segment polarity protein dishevelled homolog DVL-2
著者Cheyette, B.N.R, Waxman, J.S, Miller, J.R, Takemaru, K.-I, Sheldahl, L.C, Khlebtsova, N, Fox, E.P, Earnest, T, Moon, R.T.
登録日2002-03-11
公開日2003-06-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation
Dev.Cell, 2, 2002
1KEF
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PDZ1 of SAP90
分子名称: synapse associated protein-90
著者Piserchio, A, Pellegrini, M, Mehta, S, Blackman, S.M, Garcia, E.P, Marshall, J, Mierke, D.F.
登録日2001-11-15
公開日2002-03-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The PDZ1 domain of SAP90. Characterization of structure and binding.
J.Biol.Chem., 277, 2002

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