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PDB: 659 件

7NTK
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PALS1 PDZ1 domain with SARS-CoV-2_E PBM complex
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, Envelope small membrane protein, ...
著者Javorsky, A, Kvansakul, M.
登録日2021-03-10
公開日2021-06-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain.
Commun Biol, 4, 2021
7NTJ
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PALS1 PDZ1 domain with SARS-CoV-1_E PBM complex
分子名称: Envelope small membrane protein, MAGUK p55 subfamily member 5
著者Javorsky, A, Kvansakul, M.
登録日2021-03-10
公開日2021-06-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain.
Commun Biol, 4, 2021
7X2E
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Structure of USH1C PDZ2 and coiled-coil in complex with CDHR2 C-terminal tail
分子名称: Cadherin-related family member 2, GLYCEROL, Harmonin
著者Yan, W, Chen, G, Li, J.
登録日2022-02-25
公開日2022-07-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of the Harmonin PDZ2 and coiled-coil domains in a complex with CDHR2 tail and its implications.
Faseb J., 36, 2022
4XHV
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BU of 4xhv by Molmil
Crystal structure of Drosophila Spinophilin-PDZ and a C-terminal peptide of Neurexin
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, LP20995p, ...
著者Driller, J.H, Muhammad, K.G.H, Reddy, S, Rey, U, Boehme, M.A, Hollmann, C, Ramesh, N, Depner, H, Luetzkendorf, J, Matkovic, T, Bergeron, D, Quentin, C, Schmoranzer, J, Goettfert, F, Holt, M, Wahl, M.C, Hell, S.W, Walter, A, Sigrist, S.J, Loll, B.
登録日2015-01-06
公開日2015-07-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function.
Nat Commun, 6, 2015
6MS1
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BU of 6ms1 by Molmil
Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC
分子名称: 1,2-ETHANEDIOL, APC C-terminus peptide, Protein scribble homolog
著者How, J.Y, Kvansakul, M, Caria, S, Humbert, P.O.
登録日2018-10-16
公開日2019-02-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC.
FEBS Lett., 593, 2019
6MYE
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Crystal structure of human Scribble PDZ1 domain in complex with internal PDZ binding motif of Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF)
分子名称: FORMIC ACID, Protein scribble homolog, Rho guanine nucleotide exchange factor 26, ...
著者Sun, Y.J, Hou, T, Gakhar, L, Fuentes, E.J.
登録日2018-11-01
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility.
J.Cell Biol., 218, 2019
6MYF
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Crystal structure of free human Scribble PDZ1 domain
分子名称: Protein scribble homolog
著者Sun, Y.J, Hou, T, Gakhar, L, Fuentes, E.J.
登録日2018-11-01
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility.
J.Cell Biol., 218, 2019
6NH9
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Crystal structure of a human calcium/calmodulin dependent serine protein kinase (CASK) PDZ domain
分子名称: Peripheral plasma membrane protein CASK
著者Sun, Y.J, Gakhar, L, Fuentes, E.J.
登録日2018-12-21
公開日2019-12-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献CASK PDZ domain specificity
To be published
5ZYS
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BU of 5zys by Molmil
Structure of Nephrin/MAGI1 complex
分子名称: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1, Nephrin
著者Weng, Z.F, Shng, Y, Zhu, J.W, Zhang, R.G.
登録日2018-05-28
公開日2019-01-23
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling.
J. Am. Soc. Nephrol., 29, 2018
4AMH
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BU of 4amh by Molmil
Influence of circular permutation on the folding pathway of a PDZ domain
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DISKS LARGE HOMOLOG 1, GLYCEROL
著者Hultqvist, G, Punekar, A.S, Chi, C.N, Selmer, M, Gianni, S, Jemth, P.
登録日2012-03-10
公開日2012-12-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Tolerance of Protein Folding to a Circular Permutation in a Pdz Domain
Plos One, 7, 2012
6OV7
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CFTR Associated Ligand (CAL) PDZ domain bound to peptide kCAL01
分子名称: Golgi-associated PDZ and coiled-coil motif-containing protein, kCAL01 peptide
著者Gill, N.P, Madden, D.R.
登録日2019-05-07
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Computational Analysis of Energy Landscapes Reveals Dynamic Features That Contribute to Binding of Inhibitors to CFTR-Associated Ligand.
J.Phys.Chem.B, 123, 2019
6HKS
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BU of 6hks by Molmil
Crystal structure of the PTPN3 PDZ domain bound to the HPV16 E6 oncoprotein C-terminal peptide
分子名称: IODIDE ION, Protein E6, Tyrosine-protein phosphatase non-receptor type 3
著者Genera, M, Haouz, A, Caillet-Saguy, C.
登録日2018-09-07
公開日2019-05-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1944108 Å)
主引用文献Structural and functional characterization of the PDZ domain of the human phosphatase PTPN3 and its interaction with the human papillomavirus E6 oncoprotein.
Sci Rep, 9, 2019
6V84
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CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALAc
分子名称: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, LyCALAc
著者Gill, N.P, Madden, D.R.
登録日2019-12-10
公開日2021-02-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALAc
To Be Published
6AK2
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BU of 6ak2 by Molmil
Crystal structure of the syntenin PDZ1 domain in complex with the peptide inhibitor KSL-128018
分子名称: Syntenin-1, peptide inhibitor KSL-128018
著者Jin, Z.Y, Park, J.H, Yun, J.H, Haugaard-Kedstrom, L.M, Lee, W.T.
登録日2018-08-29
公開日2019-09-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.868 Å)
主引用文献A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma.
J.Med.Chem., 64, 2021
6AR4
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BU of 6ar4 by Molmil
Crystal structure of PICK1 in complex with the small molecule inhibitor 1o
分子名称: N-[4-(4-bromophenyl)-1-{[2-(trifluoromethyl)phenyl]methyl}piperidine-4-carbonyl]-3-cyclopropyl-L-alanine, PRKCA-binding protein
著者Marcotte, D.
登録日2017-08-21
公開日2018-08-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction.
Sci Rep, 8, 2018
6NID
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BU of 6nid by Molmil
Crystal structure of a human calcium/calmodulin dependent serine protein kinase (CASK) PDZ domain in complex with Neurexin-1 peptide
分子名称: 1,2-ETHANEDIOL, Neurexin-1, Peripheral plasma membrane protein CASK
著者Sun, Y.J, Gakhar, L, Fuentes, E.J.
登録日2018-12-27
公開日2020-01-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献CASK PDZ domain specificity
To be published
4YYX
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BU of 4yyx by Molmil
Crystal structure of the ZO-1 PDZ1 domain in complex with the 7-mer Claudin2 C-terminal tail
分子名称: FORMIC ACID, Tight junction protein ZO-1 fused with Claudin-2 C-terminal
著者Nomme, J, Lavie, A.
登録日2015-03-24
公開日2015-04-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins.
J.Biol.Chem., 290, 2015
4Z33
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Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2
分子名称: ACETATE ION, D-MYO-INOSITOL-4,5-BISPHOSPHATE, GLYCEROL, ...
著者Egea-Jimenez, A.L, Gallardo, R, Garcia-Pino, A, Ivarsson, Y, Wawrzyniak, A.M, Kashyap, R, Loris, R, Schymkowitz, J, Rousseau, F, Zimmermann, P.
登録日2015-03-30
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of the syntenin PDZ1 and PDZ2 tandem in complex with the Frizzled 7 C-terminal fragment and PIP2
To Be Published
4Z8J
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BU of 4z8j by Molmil
Crystal structure of the SNX27 PDZ domain bound to the C-terminal PTHR PDZ binding motif
分子名称: C-terminal PDZ binding motif from parathyroid hormone receptor (PTHR), Sorting nexin-27
著者Clairfeuille, T, Pavlos, N, Collins, B.M.
登録日2015-04-09
公開日2016-02-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Role of SNX27-retromer in PTHR trafficking
To Be Published
6UBH
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BU of 6ubh by Molmil
Structure of the MM7 Erbin PDZ variant in complex with a high-affinity peptide
分子名称: Erbin, SODIUM ION, peptide
著者Singer, A.U, Teyra, J, McLaughlin, M, Ernst, A, Sicheri, F, Sidhu, S.S.
登録日2019-09-11
公開日2020-07-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Comprehensive Assessment of the Relationship Between Site -2 Specificity and Helix alpha 2 in the Erbin PDZ Domain.
J.Mol.Biol., 433, 2021
6GBD
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BU of 6gbd by Molmil
Murine Protein Tyrosine Phosphatase PTPN13 PDZ3 Domain
分子名称: PDZ3
著者Kock, G, Stoll, R.
登録日2018-04-13
公開日2018-12-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Molecular Basis of Class III Ligand Recognition by PDZ3 in Murine Protein Tyrosine Phosphatase PTPN13.
J. Mol. Biol., 430, 2018
6GBE
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Murine Protein Tyrosine Phosphatase PTPN13 PDZ3 Domain-PRK2 Peptide Complex
分子名称: Serine/threonine-protein kinase N2, Tyrosine-protein phosphatase non-receptor type 13
著者Kock, G, Stoll, R.
登録日2018-04-13
公開日2018-12-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Molecular Basis of Class III Ligand Recognition by PDZ3 in Murine Protein Tyrosine Phosphatase PTPN13.
J. Mol. Biol., 430, 2018
4YDP
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BU of 4ydp by Molmil
Crystal structure of N-terminal PDZ domain of ZASP in complex with myotilin C-terminal peptide.
分子名称: GLUTAMIC ACID, LEUCINE, LIM domain-binding protein 3
著者Grishkovskaya, I, Onipe, A, Kontaxis, G, Djinovic-Carugo, K.
登録日2015-02-22
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of N-terminal PDZ domain of ZASP in complex with myotilin C-terminal peptide.
To Be Published
6BJO
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PICK1 PDZ domain in complex with the small molecule inhibitor BIO124.
分子名称: (2S)-({4-(4-bromophenyl)-1-[1-(tert-butoxycarbonyl)-L-prolyl]piperidine-4-carbonyl}amino)(cyclopentyl)acetic acid, PRKCA-binding protein
著者Marcotte, D.J.
登録日2017-11-06
公開日2018-01-10
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure.
Protein Sci., 27, 2018
6BJN
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PICK1 PDZ domain in complex with the class I PDZ binding motif QSAV
分子名称: PRKCA-binding protein
著者Marcotte, D.J.
登録日2017-11-06
公開日2018-01-10
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure.
Protein Sci., 27, 2018

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件を2024-06-26に公開中

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