1XOD
 
 | | Crystal structure of X. tropicalis Spred1 EVH-1 domain | | 分子名称: | GLYCEROL, Spred1 | | 著者 | Harmer, N.J, Sivak, J.M, Amaya, E, Blundell, T.L. | | 登録日 | 2004-10-06 | | 公開日 | 2005-01-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | 1.15A Crystal structure of the X. tropicalis Spred1 EVH1 domain suggests a fourth distinct peptide-binding mechanism within the EVH1 family
Febs Lett., 579, 2005
|
|
7LXE
 | |
2P8V
 | | Crystal structure of human Homer3 EVH1 domain | | 分子名称: | Homer protein homolog 3, SULFATE ION | | 著者 | Bouyain, S, Tu, J, Huang, G.N, Worley, P.F, Leahy, D. | | 登録日 | 2007-03-23 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins.
Science, 319, 2008
|
|
4MY6
 | | EnaH-EVH1 in complex with peptidomimetic low-molecular weight inhibitor Ac-[2-Cl-F]-[ProM-2]-[ProM-1]-OH | | 分子名称: | (3aR,5aS,8S,10aS)-1-[(3S,6R,8aS)-1'-[(2S)-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8a-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-10-oxidanylidene-2,3,3a,5a,8,10a-hexahydrodipyrrolo[3,2-b:3',1'-f]azepine-8-carboxylic acid, BROMIDE ION, Protein enabled homolog | | 著者 | Barone, M, Roske, Y, Kuehne, R. | | 登録日 | 2013-09-27 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
1QC6
 | | EVH1 domain from ENA/VASP-like protein in complex with ACTA peptide | | 分子名称: | EVH1 DOMAIN FROM ENA/VASP-LIKE PROTEIN, PHE-GLU-PHE-PRO-PRO-PRO-PRO-THR-ASP-GLU-GLU | | 著者 | Fedorov, A.A, Fedorov, E.V, Gertler, F.B, Almo, S.C. | | 登録日 | 1999-05-17 | | 公開日 | 1999-05-25 | | 最終更新日 | 2018-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of EVH1, a novel proline-rich ligand-binding module involved in cytoskeletal dynamics and neural function
Nat.Struct.Biol., 6, 1999
|
|
7AKI
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-1]-NH2 | | 分子名称: | (3~{S},7~{R},10~{R},13~{S})-4-[(3~{S},6~{R},8~{a}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-2-oxidanylidene-1,4-diazatricyclo[8.3.0.0^{3,7}]tridec-8-ene-13-carboxamide, NITRATE ION, Protein enabled homolog | | 著者 | Barone, M, Roske, Y. | | 登録日 | 2020-10-01 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
7A5M
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-17]-OMe | | 分子名称: | Ac-[2-Cl-F]-[ProM-2]-[ProM-17]-OMe, NITRATE ION, Protein enabled homolog | | 著者 | Barone, M, Roske, Y. | | 登録日 | 2020-08-21 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (0.78 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6RCF
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-15]-OH | | 分子名称: | 2-[(3~{a}~{R},6~{R},8~{a}~{S})-1-[(3~{S},6~{R},8~{a}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-6-ethyl-8-oxidanylidene-3,3~{a},6,8~{a}-tetrahydro-2~{H}-pyrrolo[2,3-c]azepin-7-yl]ethanoic acid, NITRATE ION, Protein enabled homolog | | 著者 | Barone, M, Roske, Y. | | 登録日 | 2019-04-11 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
1TJ6
 | |
3SYX
 | | Crystal Structure of the WH1 domain from human sprouty-related, EVH1 domain-containing protein. Northeast Structural Genomics Consortium Target HR5538B. | | 分子名称: | Sprouty-related, EVH1 domain-containing protein 1, YTTRIUM (III) ION | | 著者 | Vorobiev, S, Su, M, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2011-07-18 | | 公開日 | 2011-08-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.453 Å) | | 主引用文献 | Crystal Structure of the WH1 domain from human sprouty-related, EVH1 domain-containing protein.
To be Published
|
|
5ZZ9
 | | Crystal structure of Homer2 EVH1/Drebrin PPXXF complex | | 分子名称: | Homer protein homolog 2, Peptide from Drebrin | | 著者 | Li, Z, Liu, H, Li, J, Liu, W, Zhang, M. | | 登録日 | 2018-05-31 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Homer Tetramer Promotes Actin Bundling Activity of Drebrin.
Structure, 27, 2019
|
|
6RCJ
 | |
6XVT
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-PPPPTEDDL-NH2 | | 分子名称: | ACY-SC1-SC2-SC3-SC4-SC5-NME, NITRATE ION, Protein enabled homolog, ... | | 著者 | Barone, M, Le Cong, K, Roske, Y. | | 登録日 | 2020-01-22 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6RD2
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-2]-[ProM-1]-TEDEL-NH2 | | 分子名称: | (3~{S},7~{R},10~{R},13~{S})-4-[(3~{S},6~{R},8~{a}~{S})-1'-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-5-oxidanylidene-spiro[1,2,3,8~{a}-tetrahydroindolizine-6,2'-pyrrolidine]-3-yl]carbonyl-2-oxidanylidene-1,4-diazatricyclo[8.3.0.0^{3,7}]tridec-8-ene-13-carboxylic acid, GLYCEROL, NITRATE ION, ... | | 著者 | Barone, M, Roske, Y. | | 登録日 | 2019-04-12 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6XXR
 | |
1I2H
 | | CRYSTAL STRUCTURE ANALYSIS OF PSD-ZIP45(HOMER1C/VESL-1L)CONSERVED HOMER 1 DOMAIN | | 分子名称: | PSD-ZIP45(HOMER-1C/VESL-1L) | | 著者 | Irie, K, Nakatsu, T, Mitsuoka, K, Fujiyoshi, Y, Kato, H. | | 登録日 | 2001-02-09 | | 公開日 | 2002-05-29 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure of the Homer 1 Family Conserved Region Reveals the Interaction Between the EVH1 Domain and
Own Proline-rich Motif
J.Mol.Biol., 318, 2002
|
|
1I7A
 | | EVH1 DOMAIN FROM MURINE HOMER 2B/VESL 2 | | 分子名称: | CITRATE ANION, HOMER 2B, PHE-ALA-PHE, ... | | 著者 | Barzik, M, Carl, U.D, Schubert, W.-D, Wehland, J, Heinz, D.W. | | 登録日 | 2001-03-08 | | 公開日 | 2001-08-22 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | The N-terminal domain of Homer/Vesl is a new class II EVH1 domain.
J.Mol.Biol., 309, 2001
|
|
2IFS
 | |
1MKE
 | | Structure of the N-WASP EVH1 Domain-WIP complex | | 分子名称: | Fusion protein consisting of Wiskott-Aldrich syndrome protein interacting protein (WIP), GSGSG linker, and Neural Wiskott-Aldrich syndrome protein (N-WASP) | | 著者 | Volkman, B.F, Prehoda, K.E, Scott, J.A, Peterson, F.C, Lim, W.A. | | 登録日 | 2002-08-29 | | 公開日 | 2002-12-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the N-WASP EVH1 Domain-WIP Complex. Insight into the
Molecular Basis of Wiskott-Aldrich Syndrome.
Cell(Cambridge,Mass.), 111, 2002
|
|
2JP2
 | | Solution structure and resonance assignment of the N-terminal EVH1 domain from the human Spred2 protein (Sprouty-related protein with EVH1 domain isoform 2) | | 分子名称: | Sprouty-related, EVH1 domain-containing protein 2 | | 著者 | Fossi, M, Zimmermann, J, Jarchau, T, Lemak, A, Walter, U, Wiegelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Oschkinat, H, Ball, L.J, Structural Genomics Consortium (SGC) | | 登録日 | 2007-04-18 | | 公開日 | 2007-05-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | 1H, 13C and 15N resonance assignment of the human Spred2 EVH1 domain
J.Biomol.NMR, 29, 2004
|
|
1DDW
 | | HOMER EVH1 DOMAIN UNLIGANDED | | 分子名称: | GLGF-DOMAIN PROTEIN HOMER | | 著者 | Beneken, J, Tu, J.C, Xiao, B, Worley, P.F, Leahy, D.J. | | 登録日 | 1999-11-11 | | 公開日 | 2000-05-10 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition.
Neuron, 26, 2000
|
|
1DDV
 | | CRYSTAL STRUCTURE OF THE HOMER EVH1 DOMAIN WITH BOUND MGLUR PEPTIDE | | 分子名称: | GLGF-DOMAIN PROTEIN HOMER, METABOTROPIC GLUTAMATE RECEPTOR MGLUR5 | | 著者 | Beneken, J, Tu, J.C, Xiao, B, Worley, P.F, Leahy, D.J. | | 登録日 | 1999-11-11 | | 公開日 | 2000-05-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the Homer EVH1 domain-peptide complex reveals a new twist in polyproline recognition.
Neuron, 26, 2000
|
|
1EVH
 | |
1EGX
 | | SOLUTION STRUCTURE OF THE ENA-VASP HOMOLOGY 1 (EVH1) DOMAIN OF HUMAN VASODILATOR-STIMULATED PHOSPHOPROTEIN (VASP) | | 分子名称: | VASODILATOR-STIMULATED PHOSPHOPROTEIN | | 著者 | Ball, L, Kuhne, R, Hoffmann, B, Hafner, A, Schmieder, P, Volkmer-Engert, R, Hof, M, Wahl, M, Schneider-Mergener, J, Walter, U, Oschkinat, H, Jarchau, T. | | 登録日 | 2000-02-17 | | 公開日 | 2000-09-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity.
EMBO J., 19, 2000
|
|
5NAJ
 | | ENAH EVH1 in complex with Ac-[2-Cl-F]-[ProM-1]-[ProM-1]-OH | | 分子名称: | (3~{S},7~{R},10~{R},13~{S})-4-[[(3~{R},7~{S},10~{S},13~{R})-4-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-2-oxidanylidene-1,4-diazatricyclo[8.3.0.0^{3,7}]tridec-8-en-13-yl]carbonyl]-2-oxidanylidene-1,4-diazatricyclo[8.3.0.0^{3,7}]tridec-8-ene-13-carboxylic acid, (3~{S},7~{R},10~{R},13~{S})-4-[[(3~{S},7~{R},10~{R},13~{S})-4-[(2~{S})-2-acetamido-3-(2-chlorophenyl)propanoyl]-2-oxidanylidene-1,4-diazatricyclo[8.3.0.0^{3,7}]tridec-8-en-13-yl]carbonyl]-2-oxidanylidene-1,4-diazatricyclo[8.3.0.0^{3,7}]tridec-8-ene-13-carboxylic acid, CHLORIDE ION, ... | | 著者 | Barone, M, Roske, Y. | | 登録日 | 2017-02-28 | | 公開日 | 2017-05-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
