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PDB: 142 件
4Y18
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Structure of BRCA1 BRCT domains in complex with Abraxas double phosphorylated peptide
分子名称: BRCA1-A complex subunit Abraxas, Breast cancer type 1 susceptibility protein
著者Wu, Q, Blundell, T.L.
登録日2015-02-06
公開日2016-01-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites.
Mol.Cell, 61, 2016
4Y2G
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Structure of BRCA1 BRCT domains in complex with Abraxas single phosphorylated peptide
分子名称: BRCA1-A complex subunit Abraxas, Breast cancer type 1 susceptibility protein
著者Wu, Q, Blundell, T.L.
登録日2015-02-09
公開日2016-01-27
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites.
Mol.Cell, 61, 2016
3COJ
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BU of 3coj by Molmil
Crystal Structure of the BRCT Domains of Human BRCA1 in Complex with a Phosphorylated Peptide from Human Acetyl-CoA Carboxylase 1
分子名称: Acetyl-CoA carboxylase 1, Breast cancer type 1 susceptibility protein
著者Shen, Y, Tong, L.
登録日2008-03-28
公開日2008-05-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1
Biochemistry, 47, 2008
1Y98
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Structure of the BRCT repeats of BRCA1 bound to a CtIP phosphopeptide.
分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, CtIP PHOSPHORYLATED PEPTIDE, ...
著者Varma, A.K, Brown, R.S, Birrane, G, Ladias, J.A.A.
登録日2004-12-14
公開日2005-08-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Cell Cycle Checkpoint Control by the BRCA1-CtIP Complex.
Biochemistry, 44, 2005
3AL3
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BU of 3al3 by Molmil
Crystal Structure of TopBP1 BRCT7/8-BACH1 peptide complex
分子名称: DNA topoisomerase 2-binding protein 1, FORMIC ACID, Peptide of Fanconi anemia group J protein
著者Leung, C.C, Glover, J.N.
登録日2010-07-22
公開日2010-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control
J.Biol.Chem., 286, 2011
3UEN
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BU of 3uen by Molmil
Crystal structure of TopBP1 BRCT4/5 domains
分子名称: DNA topoisomerase 2-binding protein 1, GLYCEROL, THIOCYANATE ION
著者Leung, C.C, Glover, J.N.M.
登録日2011-10-31
公開日2013-07-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control.
Structure, 21, 2013
3UEO
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Crystal structure of TopBP1 BRCT4/5 domains in complex with a phospho-peptide
分子名称: DNA topoisomerase 2-binding protein 1, phospho-peptide
著者Leung, C.C, Glover, J.N.M.
登録日2011-10-31
公開日2013-07-03
最終更新日2014-03-26
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control.
Structure, 21, 2013
3AL2
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Crystal Structure of TopBP1 BRCT7/8
分子名称: DNA topoisomerase 2-binding protein 1, SULFATE ION
著者Leung, C.C, Glover, J.N.
登録日2010-07-22
公開日2010-12-01
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control
J.Biol.Chem., 286, 2011
2COK
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Solution structure of BRCT domain of poly(ADP-ribose) polymerase-1
分子名称: Poly [ADP-ribose] polymerase-1
著者Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-17
公開日2005-11-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of BRCT domain of poly(ADP-ribose) polymerase-1
To be Published
1T29
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Crystal structure of the BRCA1 BRCT repeats bound to a phosphorylated BACH1 peptide
分子名称: BACH1 phosphorylated peptide, Breast cancer type 1 susceptibility protein
著者Shiozaki, E.N, Gu, L, Yan, N, Shi, Y.
登録日2004-04-20
公開日2004-05-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling.
Mol.Cell, 14, 2004
2LE0
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PARP BRCT Domain
分子名称: Poly [ADP-ribose] polymerase 1
著者Mueller, G, Loeffler, P, Cuneo, M, Derose, E, London, R.
登録日2011-06-03
公開日2011-10-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural studies of the PARP-1 BRCT domain.
Bmc Struct.Biol., 11, 2011
1T2V
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Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide
分子名称: BRCTide-7PS, Breast cancer type 1 susceptibility protein
著者Williams, R.S, Lee, M.S, Hau, D.D, Glover, J.N.M.
登録日2004-04-22
公開日2004-05-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
6J0W
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Crystal Structure of Yeast Rtt107 and Nse6
分子名称: Peptide from DNA repair protein KRE29, Regulator of Ty1 transposition protein 107
著者Wan, B, Wu, J, Lei, M.
登録日2018-12-27
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107.
Mol.Cell, 75, 2019
1T2U
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Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F
分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
著者Williams, R.S, Lee, M.S, Duong, D.D, Glover, J.N.M.
登録日2004-04-22
公開日2004-05-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1
Nat.Struct.Mol.Biol., 11, 2004
1T15
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Crystal Structure of the Brca1 BRCT Domains in Complex with the Phosphorylated Interacting Region from Bach1 Helicase
分子名称: BRCA1 interacting protein C-terminal helicase 1, Breast cancer type 1 susceptibility protein
著者Clapperton, J.A, Manke, I.A, Lowery, D.M, Ho, T, Haire, L.F, Yaffe, M.B, Smerdon, S.J.
登録日2004-04-15
公開日2004-05-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer
Nat.Struct.Mol.Biol., 11, 2004
6J0V
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Crystal Structure of Yeast Rtt107
分子名称: Regulator of Ty1 transposition protein 107
著者Wan, B, Wu, J, Lei, M.
登録日2018-12-27
公開日2019-08-14
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.314 Å)
主引用文献Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107.
Mol.Cell, 75, 2019
6J0Y
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Crystal Structure of Yeast Rtt107 and Slx4
分子名称: Peptide from Structure-specific endonuclease subunit SLX4, Regulator of Ty1 transposition protein 107
著者Wan, B, Wu, J, Lei, M.
登録日2018-12-27
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107.
Mol.Cell, 75, 2019
6J0X
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Crystal Structure of Yeast Rtt107 and Mms22
分子名称: Peptide from E3 ubiquitin-protein ligase substrate receptor MMS22, Regulator of Ty1 transposition protein 107
著者Wan, B, Wu, J, Lei, M.
登録日2018-12-27
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Molecular Basis for Control of Diverse Genome Stability Factors by the Multi-BRCT Scaffold Rtt107.
Mol.Cell, 75, 2019
4BMD
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BU of 4bmd by Molmil
Crystal structure of S.pombe Rad4 BRCT3,4
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, S-M CHECKPOINT CONTROL PROTEIN RAD4
著者Meng, Q, Rappas, M, Wardlaw, C.P, Garcia, V, Carr, A.M, Oliver, A.W, Du, L.L, Pearl, L.H.
登録日2013-05-07
公開日2013-10-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Phosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4(Topbp1.).
Mol.Cell, 51, 2013
2ING
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BU of 2ing by Molmil
X-ray Structure of the BRCA1 BRCT mutant M1775K
分子名称: Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION
著者Birrane, G, Soni, A, Ladias, J.A.A.
登録日2006-10-07
公開日2007-09-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach.
Eur.J.Hum.Genet., 16, 2008
2K6G
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Solution structure of the DNA binding BRCT domain from the large subunit of human Replication Factor C
分子名称: Replication factor C subunit 1
著者Kobayashi, M, Siegal, G, Ab, E, Bonvin, A.M.J.J.
登録日2008-07-09
公開日2009-09-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA bound BRCT domain from human Replication Factor C p140
To be Published
2K7F
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HADDOCK calculated model of the complex between the BRCT region of RFC p140 and dsDNA
分子名称: 5'-D(P*DCP*DGP*DAP*DCP*DCP*DTP*DCP*DGP*DAP*DGP*DAP*DTP*DCP*DA)-3', 5'-D(P*DCP*DTP*DCP*DGP*DAP*DGP*DGP*DTP*DCP*DG)-3', Replication factor C subunit 1
著者Kobayashi, M, Ab, E, Bonvin, A, Siegal, G.
登録日2008-08-10
公開日2009-09-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the DNA-bound BRCA1 C-terminal region from human replication factor C p140 and model of the protein-DNA complex.
J.Biol.Chem., 285, 2010
2COE
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BU of 2coe by Molmil
Solution structure of BRCT domain of terminal deoxynucleotidyltransferase
分子名称: deoxynucleotidyltransferase, terminal variant
著者Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-17
公開日2005-11-17
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of BRCT domain of terminal deoxynucleotidyltransferase
To be Published
2EBU
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Solution structure of the BRCT domain from human replication factor C large subunit 1
分子名称: Replication factor C subunit 1
著者Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-09
公開日2007-08-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the BRCT domain from human replication factor C large subunit 1
To be Published
2EBW
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Solution structure of the BRCT domain from human DNA repair protein REV1
分子名称: DNA repair protein REV1
著者Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-02-09
公開日2007-08-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the BRCT domain from human DNA repair protein REV1
To be Published

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