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PDB: 109 件
3VA7
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Crystal structure of the Kluyveromyces lactis Urea Carboxylase
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, GLYCEROL, KLLA0E08119p, ...
著者Fan, C, Xiang, S.
登録日2011-12-29
公開日2012-02-01
最終更新日2013-07-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of urea carboxylase provides insights into the carboxyltransfer reaction
J.Biol.Chem., 287, 2012
2QF7
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BU of 2qf7 by Molmil
Crystal structure of a complete multifunctional pyruvate carboxylase from Rhizobium etli
分子名称: CHLORIDE ION, COENZYME A, FORMIC ACID, ...
著者St Maurice, M, Surinya, K.H, Rayment, I.
登録日2007-06-27
公開日2007-09-04
最終更新日2012-02-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme
Science, 317, 2007
6OI9
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BU of 6oi9 by Molmil
Crystal Structure of E. coli Biotin Carboxylase Complexed with 7-[3-(aminomethyl)pyrrolidin-1-yl]-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-2-amine
分子名称: 1,2-ETHANEDIOL, 7-[(3S)-3-(aminomethyl)pyrrolidin-1-yl]-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-2-amine, Biotin carboxylase
著者Andrews, L.D, Kane, T.R, Dozzo, P, Haglund, C.M, Hilderbrandt, D.J, Linsell, M.S, Machajewski, T, McEnroe, G, Serio, A.W, Wlasichuk, K.B, Neau, D.B, Pakhomova, S, Waldrop, G.L, Sharp, M, Pogliano, J, Cirz, R, Cohen, F.
登録日2019-04-09
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Optimization and Mechanistic Characterization of Pyridopyrimidine Inhibitors of Bacterial Biotin Carboxylase.
J.Med.Chem., 62, 2019
7YBU
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BU of 7ybu by Molmil
Human propionyl-coenzyme A carboxylase
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-CoA carboxylase alpha chain, mitochondrial, ...
著者Su, J.Y, Liu, D.S.
登録日2022-06-29
公開日2023-07-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Human propionyl-coenzyme A carboxylase
To Be Published
5H80
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BU of 5h80 by Molmil
Biotin Carboxylase domain of single-chain bacterial carboxylase
分子名称: 1,2-ETHANEDIOL, Carboxylase
著者Hagmann, A, Hunkeler, M, Stuttfeld, E, Maier, T.
登録日2015-12-23
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Hybrid Structure of a Dynamic Single-Chain Carboxylase from Deinococcus radiodurans.
Structure, 24, 2016
5MLK
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BU of 5mlk by Molmil
Biotin dependent carboxylase AccA3 dimer from Mycobacterium tuberculosis (Rv3285)
分子名称: Acetyl-COA carboxylase
著者Bennett, M.D, Hogbom, M.
登録日2016-12-07
公開日2017-03-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.939 Å)
主引用文献Crystal structure of the essential biotin-dependent carboxylase AccA3 from Mycobacterium tuberculosis.
FEBS Open Bio, 7, 2017
6OJH
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Crystal Structure of Haemophilus Influenzae Biotin Carboxylase Complexed with (R)-7-(3-aminopyrrolidin-1-yl)-6-(naphthalen-1-yl)pyrido[2,3-d]pyrimidin-2-amine
分子名称: 7-[(3R)-3-aminopyrrolidin-1-yl]-6-(naphthalen-1-yl)pyrido[2,3-d]pyrimidin-2-amine, ACETATE ION, Biotin carboxylase, ...
著者Andrews, L.D, Kane, T.R, Dozzo, P, Haglund, C.M, Hilderbrandt, D.J, Linsell, M.S, Machajewski, T, McEnroe, G, Serio, A.W, Wlasichuk, K.B, Neau, D.B, Pakhomova, S, Waldrop, G.L, Sharp, M, Pogliano, J, Cirz, R, Cohen, F.
登録日2019-04-11
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of Haemophilus Influenzae Biotin Carboxylase Complexed with (R)-7-(3-aminopyrrolidin-1-yl)-6-(naphthalen-1-yl)pyrido[2,3-d]pyrimidin-2-amine
To Be Published
6YBQ
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BU of 6ybq by Molmil
Engineered glycolyl-CoA carboxylase (quintuple mutant) with bound CoA
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ...
著者Schuller, J.M, Schuller, S.K, Zarzycki, J, Scheffen, M, Marchal, D.M, Erb, T.J.
登録日2020-03-17
公開日2020-10-28
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (1.96 Å)
主引用文献A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation
Nat Catal, 2021
2C00
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BU of 2c00 by Molmil
Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa in apo form
分子名称: BIOTIN CARBOXYLASE, SULFATE ION
著者Mochalkin, I.
登録日2008-03-21
公開日2008-09-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
6YBP
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BU of 6ybp by Molmil
Propionyl-CoA carboxylase of Methylorubrum extorquens with bound CoA
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ...
著者Schuller, J.M, Schuller, S.K, Zarzycki, J, Scheffen, M, Marchal, D.M, Erb, T.J.
登録日2020-03-17
公開日2020-10-28
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献A new-to-nature carboxylation module to improve natural and synthetic CO2 fixation
Nat Catal, 2021
2YL2
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BU of 2yl2 by Molmil
Crystal structure of human acetyl-CoA carboxylase 1, biotin carboxylase (BC) domain
分子名称: ACETYL-COA CARBOXYLASE 1
著者Muniz, J.R.C, Froese, D.S, Krysztofinska, E, Vollmar, M, Beltrami, A, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Yue, W.W, Oppermann, U.
登録日2011-05-31
公開日2011-06-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Human Acetyl-Coa Carboxylase 1, Biotin Carboxylase (Bc) Domain
To be Published
5CSK
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BU of 5csk by Molmil
Crystal structure of yeast acetyl-CoA carboxylase, unbiotinylated
分子名称: Acetyl-CoA carboxylase
著者Wei, J, Tong, L.
登録日2015-07-23
公開日2015-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer.
Nature, 526, 2015
6OI8
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BU of 6oi8 by Molmil
Crystal Structure of Haemophilus Influenzae Biotin Carboxylase Complexed with 7-((1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-6-(2-chloro-6-(pyridin-3-yl)phenyl)pyrido[2,3-d]pyrimidin-2-amine
分子名称: 1,2-ETHANEDIOL, 7-[(1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-6-[2-chloro-6-(pyridin-3-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine, Biotin carboxylase
著者Andrews, L.D, Kane, T.R, Dozzo, P, Haglund, C.M, Hilderbrandt, D.J, Linsell, M.S, Machajewski, T, McEnroe, G, Serio, A.W, Wlasichuk, K.B, Neau, D.B, Pakhomova, S, Waldrop, G.L, Sharp, M, Pogliano, J, Cirz, R, Cohen, F.
登録日2019-04-09
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Optimization and Mechanistic Characterization of Pyridopyrimidine Inhibitors of Bacterial Biotin Carboxylase.
J.Med.Chem., 62, 2019
3BG5
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BU of 3bg5 by Molmil
Crystal Structure of Staphylococcus Aureus Pyruvate Carboxylase
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
著者Xiang, S, Tong, L.
登録日2007-11-26
公開日2008-02-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction.
Nat.Struct.Mol.Biol., 15, 2008
4RZQ
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BU of 4rzq by Molmil
Structural Analysis of Substrate, Reaction Intermediate and Product Binding in Haemophilus influenzae Biotin Carboxylase
分子名称: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, methyl (3aS,4S,6aR)-4-(5-methoxy-5-oxopentyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazole-1-carboxylate
著者Broussard, T.C, Pakhomova, S, Neau, D.B, Champion, T.S, Bonnot, R, Waldrop, G.L.
登録日2014-12-23
公開日2015-06-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase.
Biochemistry, 54, 2015
5CSL
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BU of 5csl by Molmil
Crystal structure of the 500 kD yeast acetyl-CoA carboxylase holoenzyme dimer
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Acetyl-CoA carboxylase, COENZYME A
著者Wei, J, Tong, L.
登録日2015-07-23
公開日2015-10-28
最終更新日2022-03-23
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer.
Nature, 526, 2015
2DZD
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BU of 2dzd by Molmil
Crystal structure of the biotin carboxylase domain of pyruvate carboxylase
分子名称: pyruvate carboxylase
著者Kondo, S, Nakajima, Y, Sugio, S, Sueda, S, Islam, M.N, Kondo, H.
登録日2006-09-27
公開日2007-09-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the biotin carboxylase domain of pyruvate carboxylase from Bacillus thermodenitrificans
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
8F41
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3-methylcrotonyl-CoA carboxylase in filament, alpha-subunit centered
分子名称: 3-methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit, ...
著者Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H.
登録日2022-11-10
公開日2023-01-11
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.
Structure, 31, 2023
8F3D
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BU of 8f3d by Molmil
3-methylcrotonyl-CoA carboxylase in filament, beta-subunit centered
分子名称: 3-methylcrotonyl-CoA carboxylase alpha-subunit, 3-methylcrotonyl-CoA carboxylase beta-subunit, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL
著者Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H.
登録日2022-11-09
公開日2023-01-11
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.
Structure, 31, 2023
4RCN
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BU of 4rcn by Molmil
Structure and function of a single-chain, multi-domain long-chain acyl-coa carboxylase
分子名称: long-chain acyl-CoA carboxylase
著者Tran, T.H, Tong, L.
登録日2014-09-16
公開日2014-11-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase.
Nature, 518, 2015
3OUU
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BU of 3ouu by Molmil
Crystal Structure of Biotin Carboxylase-beta-gamma-ATP Complex from Campylobacter jejuni
分子名称: Biotin carboxylase, CACODYLATE ION, CALCIUM ION, ...
著者Maltseva, N, Kim, Y, Makowska-Grzyska, M, Mulligan, R, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-09-15
公開日2010-10-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.252 Å)
主引用文献Crystal Structure of Biotin Carboxylase-beta-gamma-ATP Complex from Campylobacter jejuni
TO BE PUBLISHED
3OUZ
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BU of 3ouz by Molmil
Crystal Structure of Biotin Carboxylase-ADP complex from Campylobacter jejuni
分子名称: ADENOSINE-5'-DIPHOSPHATE, Biotin carboxylase, D-MALATE, ...
著者Maltseva, N, Kim, Y, Makowska-Grzyska, M, Mulligan, R, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-09-15
公開日2010-10-13
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Crystal Structure of Biotin Carboxylase-ADP complex from Campylobacter jejuni
TO BE PUBLISHED
1BNC
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BU of 1bnc by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE BIOTIN CARBOXYLASE SUBUNIT OF ACETYL-COA CARBOXYLASE
分子名称: BIOTIN CARBOXYLASE, PHOSPHATE ION
著者Waldrop, G, Rayment, I, Holden, H.M.
登録日1994-07-06
公開日1995-08-30
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase.
Biochemistry, 33, 1994
7KCT
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BU of 7kct by Molmil
Crystal Structure of the Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase (OGC) Biotin Carboxylase (BC) Domain Dimer in Complex with Adenosine 5'-Diphosphate Magnesium Salt (MgADP), Adenosine 5'-Diphosphate (ADP, and Bicarbonate Anion (Hydrogen Carbonate/HCO3-)
分子名称: 2-oxoglutarate carboxylase small subunit, ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, ...
著者Buhrman, G.K, Rose, R.B, Enriquez, P, Truong, V.
登録日2020-10-07
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structure, Function, and Thermal Adaptation of the Biotin Carboxylase Domain Dimer from Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase.
Biochemistry, 60, 2021
3N6R
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BU of 3n6r by Molmil
CRYSTAL STRUCTURE OF the holoenzyme of PROPIONYL-COA CARBOXYLASE (PCC)
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-CoA carboxylase, alpha subunit, ...
著者Huang, C.S, Sadre-Bazzaz, K, Tong, L.
登録日2010-05-26
公開日2010-08-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase.
Nature, 466, 2010

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