4RZQ

Structural Analysis of Substrate, Reaction Intermediate and Product Binding in Haemophilus influenzae Biotin Carboxylase

Summary for 4RZQ

• Entry DOI: 10.2210/pdb4rzq/pdb
• Descriptor: Biotin carboxylase, methyl (3aS,4S,6aR)-4-(5-methoxy-5-oxopentyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazole-1-carboxylate, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: atp grasp, carboxylase, biotin carboxyl carrier protein and carboxyltransferase, ligase
• Biological source: Haemophilus influenzae Rd KW20
• Total number of polymer chains: 1
• Total formula weight: 52090.13

Authors

Broussard, T.C.,Pakhomova, S.,Neau, D.B.,Champion, T.S.,Bonnot, R.,Waldrop, G.L. (deposition date: 2014-12-23, release date: 2015-06-10, Last modification date: 2023-09-20)

• Primary citation: Broussard, T.C.,Pakhomova, S.,Neau, D.B.,Bonnot, R.,Waldrop, G.L.; Structural Analysis of Substrate, Reaction Intermediate, and Product Binding in Haemophilus influenzae Biotin Carboxylase.; Biochemistry, 54:3860-3870, 2015; PubMed: 26020841; DOI: 10.1021/acs.biochem.5b00340

Experimental method

X-RAY DIFFRACTION (1.98 Å)