4RZQ

Structural Analysis of Substrate, Reaction Intermediate and Product Binding in Haemophilus influenzae Biotin Carboxylase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Biotin carboxylase	polymer	468	51346.6	1	UniProt (P43873) Pfam (PF00289) Pfam (PF02786) Pfam (PF02785) In PDB	Haemophilus influenzae Rd KW20	Acetyl-CoA carboxylase subunit A, ACC
2	A	methyl (3aS,4S,6aR)-4-(5-methoxy-5-oxopentyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazole-1-carboxylate	non-polymer		316.4	1	Chemie (Y7Y)
3	A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
4		water	water		18.0	84	Chemie (HOH)

Sequence modifications

A: 1 - 448 (UniProt: P43873)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	51346.6
Non-Polymers*	Number of molecules	2
	Total formula weight	743.6
All*	Total formula weight	52090.1

*Water molecules are not included.