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PDB: 1515 件
5YDR
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BU of 5ydr by Molmil
Structure of DNMT1 RFTS domain in complex with ubiquitin
分子名称: DNA (cytosine-5)-methyltransferase 1, PHOSPHATE ION, Polyubiquitin-B, ...
著者Qian, C.
登録日2017-09-14
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation.
Nucleic Acids Res., 46, 2018
5YIK
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BU of 5yik by Molmil
Structure of a Legionella effector with its substrate
分子名称: SdeA, ubiquitin
著者Feng, Y, Dong, Y, Liu, Z.
登録日2017-10-05
公開日2018-05-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
5YIJ
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BU of 5yij by Molmil
Structure of a Legionella effector with substrates
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, SdeA, Ubiquitin
著者Feng, Y, Mu, Y, Wang, H.
登録日2017-10-05
公開日2018-05-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
5YMY
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BU of 5ymy by Molmil
The structure of the complex between Rpn13 and K48-diUb
分子名称: Proteasomal ubiquitin receptor ADRM1, Ubiquitin
著者Liu, Z, Dong, X, Gong, Z, Yi, H.W, Liu, K, Yang, J, Zhang, W.P, Tang, C.
登録日2017-10-22
公開日2019-03-13
最終更新日2019-04-24
実験手法SOLUTION NMR
主引用文献Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13.
Cell Discov, 5, 2019
5ZQ4
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BU of 5zq4 by Molmil
PDE-Ubi-ADPr
分子名称: ADENOSINE MONOPHOSPHATE, SidE, ubiquitin
著者Wang, Y, Gao, A, Gao, P.
登録日2018-04-17
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.217 Å)
主引用文献Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
5W8T
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BU of 5w8t by Molmil
Crystal structure of MERS-CoV papain-like protease in complex with the C-terminal domain of human ISG15
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ORF1ab, Ubiquitin-like protein ISG15, ...
著者Daczkowski, C.M, Goodwin, O.Y, Dzimianski, J.V, Farhat, J.J, Pegan, S.D.
登録日2017-06-22
公開日2017-09-27
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.758 Å)
主引用文献Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus.
J. Virol., 91, 2017
5W8U
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BU of 5w8u by Molmil
Crystal structure of MERS-CoV papain-like protease in complex with the C-terminal domain of human ISG15
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ORF1ab, Ubiquitin-like protein ISG15, ...
著者Daczkowski, C.M, Goodwin, O.Y, Dzimianski, J.D, Pegan, S.D.
登録日2017-06-22
公開日2017-09-27
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.411 Å)
主引用文献Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus.
J. Virol., 91, 2017
5WVO
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BU of 5wvo by Molmil
Crystal structure of DNMT1 RFTS domain in complex with K18/K23 mono-ubiquitylated histone H3
分子名称: DNA (cytosine-5)-methyltransferase 1, Histone H3.1, Ubiquitin, ...
著者Ishiyama, S, Nishiyama, A, Nakanishi, M, Arita, K.
登録日2016-12-28
公開日2017-11-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance
Mol. Cell, 68, 2017
5ZQ3
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BU of 5zq3 by Molmil
PDE-Ubiquitin
分子名称: SidE, Ubiquitin
著者Wang, Y, Gao, A, Gao, P.
登録日2018-04-17
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.182 Å)
主引用文献Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
5XVE
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BU of 5xve by Molmil
Crystal structure of human USP2 C276S mutant in complex with ubiquitin
分子名称: Ubiquitin carboxyl-terminal hydrolase 2, Ubiquitin-40S ribosomal protein S27a, ZINC ION
著者Chou, C.Y, Tang, H.C.
登録日2017-06-27
公開日2018-02-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献6-Thioguanine is a noncompetitive and slow binding inhibitor of human deubiquitinating protease USP2
Sci Rep, 8, 2018
5ZQ5
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BU of 5zq5 by Molmil
SidE-Ubi
分子名称: SidE, Ubiquitin
著者Wang, Y, Gao, A, Gao, P.
登録日2018-04-17
公開日2018-05-23
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (2.487 Å)
主引用文献Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
5WQ4
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BU of 5wq4 by Molmil
Crystal structure of OPTN and linear diubiquitin complex
分子名称: Optineurin, ubiquitin
著者Li, F, Pan, L.
登録日2016-11-23
公開日2017-12-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation.
Autophagy, 14, 2018
5ZBI
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BU of 5zbi by Molmil
Crystal structure of asparaginyl endopeptidases from Viola Canadensis
分子名称: Peptide asparaginyl ligase, SODIUM ION
著者Wong, Y.H, Lescar, J.
登録日2018-02-12
公開日2018-05-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Crystal structure of Peptide asparaginyl ligase from Viola canadensis
To Be Published
5ZQ7
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BU of 5zq7 by Molmil
SidE-Ubi-NAD
分子名称: ADENOSINE MONOPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SidE, ...
著者Wang, Y, Gao, A, Gao, P.
登録日2018-04-17
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.847 Å)
主引用文献Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
5ZQ6
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BU of 5zq6 by Molmil
SidE-Ubi-ADPr
分子名称: ADENOSINE-5'-DIPHOSPHATE, SidE, Ubiquitin
著者Wang, Y, Gao, A, Gao, P.
登録日2018-04-17
公開日2018-05-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.009 Å)
主引用文献Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
6A43
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BU of 6a43 by Molmil
R1EN(5-225)-ubiquitin fusion
分子名称: ACETIC ACID, RNA-directed DNA polymerase homolog (R1),Polyubiquitin-C
著者Maita, N.
登録日2018-06-19
公開日2018-10-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure Determination of Ubiquitin by Fusion to a Protein That Forms a Highly Porous Crystal Lattice
J. Am. Chem. Soc., 140, 2018
6A44
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BU of 6a44 by Molmil
R1EN(5-227)-ubiquitin fusion
分子名称: ACETIC ACID, RNA-directed DNA polymerase homolog (R1),Polyubiquitin-C
著者Maita, N.
登録日2018-06-19
公開日2018-10-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure Determination of Ubiquitin by Fusion to a Protein That Forms a Highly Porous Crystal Lattice
J. Am. Chem. Soc., 140, 2018
8ST7
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BU of 8st7 by Molmil
Structure of E3 ligase VsHECT bound to ubiquitin
分子名称: E3 ubiquitin-protein ligase SopA-like catalytic domain-containing protein, Ubiquitin, prop-2-en-1-amine
著者Franklin, T.G, Pruneda, J.N.
登録日2023-05-09
公開日2023-07-12
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
8ST9
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BU of 8st9 by Molmil
Structure of E3 ligase NleL bound to ubiquitin
分子名称: E3 ubiquitin-protein ligase SopA, Ubiquitin, prop-2-en-1-amine
著者Franklin, T.G, Pruneda, J.N.
登録日2023-05-09
公開日2023-07-12
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
8ST8
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BU of 8st8 by Molmil
Structure of E3 ligase SopA bound to ubiquitin
分子名称: E3 ubiquitin-protein ligase SopA, Ubiquitin, prop-2-en-1-amine
著者Franklin, T.G, Pruneda, J.N.
登録日2023-05-09
公開日2023-07-12
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
6JH1
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BU of 6jh1 by Molmil
Crystal structure of bISG15/NS1B complex
分子名称: Non-structural protein 1, Ubiquitin-like protein ISG15
著者Jiang, Y.N, Wang, X.W.
登録日2019-02-16
公開日2019-10-16
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of bISG15/NS1B complex
To Be Published
6J62
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BU of 6j62 by Molmil
Crystal structure of mISG15/NS1B complex
分子名称: Non-structural protein 1, Ubiquitin-like protein ISG15
著者Jiang, Y.N, Wang, X.Q.
登録日2019-01-12
公開日2019-12-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.486 Å)
主引用文献Crystal structure of mISG15/NS1B complex
To Be Published
8SH2
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BU of 8sh2 by Molmil
KLHDC2 in complex with EloB and EloC
分子名称: Elongin-B, Elongin-C, Kelch domain-containing protein 2
著者Digianantonio, K.M, Bekes, M.
登録日2023-04-13
公開日2024-01-03
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.74 Å)
主引用文献Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules.
Nat.Struct.Mol.Biol., 31, 2024
8SVG
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BU of 8svg by Molmil
Ubiquitin variant i53 in complex with 53BP1 Tudor domain
分子名称: Tumor protein p53 binding protein 1, Ubiquitin variant i53
著者Holden, J.K, Partridge, J.R, Wibowo, A.S, Mulichak, A.
登録日2023-05-16
公開日2024-03-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024
8SVH
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BU of 8svh by Molmil
Ubiquitin variant i53 mutant L67R bound to 53BP1 Tudor Domain
分子名称: Tumor protein p53 binding protein 1, Ubiquitin variant i53: mutant L67R
著者Holden, J.K, Partridge, J.R, Wibowo, A.S, Mulichak, A.
登録日2023-05-16
公開日2024-03-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair.
Nat Commun, 15, 2024

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