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PDB: 202 件
1RH8
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Three-dimensional structure of the calcium-free Piccolo C2A-domain
分子名称: Piccolo protein
著者Garcia, J, Gerber, S.H, Sugita, S, Sudhof, T.C, Rizo, J.
登録日2003-11-14
公開日2004-01-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A conformational switch in the Piccolo C2A domain regulated by alternative splicing.
Nat.Struct.Mol.Biol., 11, 2004
1RLW
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BU of 1rlw by Molmil
CALCIUM-PHOSPHOLIPID BINDING DOMAIN FROM CYTOSOLIC PHOSPHOLIPASE A2
分子名称: CADMIUM ION, CALCIUM ION, PHOSPHOLIPASE A2
著者Perisic, O, Williams, R.L.
登録日1997-10-28
公開日1998-02-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2.
J.Biol.Chem., 273, 1998
3N5A
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Synaptotagmin-7, C2B-domain, calcium bound
分子名称: CALCIUM ION, Synaptotagmin-7
著者Tomchick, D.R, Rizo, J, Craig, T.K.
登録日2010-05-24
公開日2010-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.441 Å)
主引用文献Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7.
Plos One, 5, 2010
3PYC
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BU of 3pyc by Molmil
Crystal structure of human SMURF1 C2 domain
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase SMURF1, SULFATE ION
著者Li, X, Li, P.
登録日2010-12-13
公開日2011-04-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structure of human SMURF1 C2 domain
To be Published
8FAM
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Edited Octopus bimaculoides Synaptotagmin 1 C2A (I248V) at room temperature
分子名称: Synaptotagmin
著者McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.J, Sutton, R.B.
登録日2022-11-28
公開日2023-07-19
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Temperature-dependent RNA editing in octopus extensively recodes the neural proteome.
Cell, 186, 2023
8FAF
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Unedited Octopus bimaculoides Synaptotagmin 1 C2A at room temperature
分子名称: Synaptotagmin
著者McNeme, S, Dominguez, M.J, Birk, M.A, Rosenthal, J.C, Sutton, R.B.
登録日2022-11-26
公開日2023-07-19
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Temperature-dependent RNA editing in octopus extensively recodes the neural proteome.
Cell, 186, 2023
2LHA
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Solution structure of C2B with IP6
分子名称: INOSITOL HEXAKISPHOSPHATE, Synaptotagmin-1
著者Joung, M, Mohan, S.K, Yu, C.
登録日2011-08-08
公開日2012-05-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Molecular Level Interaction of Inositol Hexaphosphate with the C2B Domain of Human Synaptotagmin I
Biochemistry, 2012
6ANK
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Synaptotagmin-7, C2A- and C2B-domains
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Synaptotagmin-7
著者Tomchick, D.R, Rizo, J, Voleti, R.
登録日2017-08-13
公開日2017-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.254 Å)
主引用文献Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6BTZ
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Crystal structure of the PI3KC2alpha C2 domain in space group C121
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, GLYCEROL, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, ...
著者Chen, K.-E, Collins, B.M.
登録日2017-12-08
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
2NSQ
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Crystal structure of the C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase NEDD4-like protein, GLYCEROL
著者Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-11-06
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The C2 domain of the human E3 ubiquitin-protein ligase NEDD4-like protein
To be Published
4RJ9
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Structure of a plant specific C2 domain protein, OsGAP1 from rice
分子名称: C2 domain-containing protein-like, POTASSIUM ION
著者Miao, R, Fong, Y.H, Wong, K.B, Lam, H.M.
登録日2014-10-08
公開日2015-08-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Site-directed Mutagenesis Shows the Significance of Interactions with Phospholipids and the G-protein OsYchF1 for the Physiological Functions of the Rice GTPase-activating Protein 1 (OsGAP1).
J.Biol.Chem., 290, 2015
6BTY
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Crystal structure of the PI3KC2alpha C2 domain in space group P41212
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
著者Chen, K.-E, Collins, B.M.
登録日2017-12-08
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.678 Å)
主引用文献Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
4TS6
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BU of 4ts6 by Molmil
Crystal structure of the RIM C2A domain from Drosophila.
分子名称: GLYCEROL, Rab3 interacting molecule variant 2
著者Hatzopoulos, G.N, Shiroma, J, Vakonakis, I.
登録日2014-06-18
公開日2015-07-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystal structure of the RIM C2A domain from Drosophila.
To Be Published
6BU0
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Crystal structure of the PI3KC2alpha C2 domain in complex with IP6
分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, FORMIC ACID, INOSITOL HEXAKISPHOSPHATE, ...
著者Chen, K.-E, Collins, B.M.
登録日2017-12-08
公開日2018-10-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.427 Å)
主引用文献Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2 alpha.
Structure, 26, 2018
6ANJ
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Synaptotagmin-7, C2A domain
分子名称: ACETATE ION, CALCIUM ION, Synaptotagmin-7, ...
著者Tomchick, D.R, Rizo, J, Voleti, R.
登録日2017-08-13
公開日2017-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6CXW
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Synaptotagmin 1 C2A beta4 chimera with enhanced PIP2 binding function
分子名称: Synaptotagmin 1 C2A beta4 chimera
著者Sutton, R.B.
登録日2018-04-04
公開日2019-04-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.832 Å)
主引用文献Engineering a C2-domain to bind PIP2
To Be Published
2Q3X
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The RIM1alpha C2B domain
分子名称: CHLORIDE ION, Regulating synaptic membrane exocytosis protein 1, SODIUM ION, ...
著者Guan, R, Dai, H, Tomchick, D.R, Machius, M, Sudhof, T.C, Rizo, J.
登録日2007-05-30
公開日2007-08-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Crystal Structure of the RIM1alpha C(2)B Domain at 1.7 A Resolution.
Biochemistry, 46, 2007
2NQ3
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Crystal structure of the C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase
分子名称: CHLORIDE ION, Itchy homolog E3 ubiquitin protein ligase
著者Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-10-30
公開日2006-11-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The C2 Domain of Human Itchy Homolog E3 Ubiquitin Protein Ligase
To be Published
2NCE
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BU of 2nce by Molmil
Solution Structure of Ca2+-bound C2 domain from Protein Kinase C alpha in the form of complex with V5-pHM peptide
分子名称: CALCIUM ION, Protein kinase C alpha type
著者Yang, Y, Igumenova, T.I.
登録日2016-03-28
公開日2017-03-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Ca2+-sensing domain contributes to auto-inhibition of protein kinase Calpha through interactions with C-terminal tail
To be Published
2K3H
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BU of 2k3h by Molmil
Structural determinants for Ca2+ and PIP2 binding by the C2A domain of rabphilin-3A
分子名称: CALCIUM ION, Rabphilin-3A
著者Coudevylle, N, Montaville, P, Leonov, A, Zweckstetter, M, Becker, S.
登録日2008-05-08
公開日2008-10-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural Determinants for Ca2+ and Phosphatidylinositol 4,5-Bisphosphate Binding by the C2A Domain of Rabphilin-3A.
J.Biol.Chem., 283, 2008
2JQZ
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Solution Structure of the C2 domain of human Smurf2
分子名称: E3 ubiquitin-protein ligase SMURF2
著者Wiesner, S, Ogunjimi, A.A, Wang, H, Rotin, D, Sicheri, F, Wrana, J.L, Forman-Kay, J.D.
登録日2007-06-15
公開日2007-09-11
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Autoinhibition of the HECT-Type Ubiquitin Ligase Smurf2 through Its C2 Domain
Cell(Cambridge,Mass.), 130, 2007
2K45
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C2A domain of synaptototagmin I solution structure in the FGF-1-C2A binary complex: key component in the fibroblast growthfactor non-classical pathway
分子名称: Synaptotagmin-1
著者Mohan, S.K, Yu, C.
登録日2008-05-28
公開日2009-06-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献FGF-1-C2A binary complex structure: key component in the acidic fibroblast growth factor release
To be Published
3F05
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Crystal Structure of Synaptotagmin I C2A domain with Mn(II)
分子名称: MANGANESE (II) ION, SULFATE ION, Synaptotagmin-1
著者Guo, F, Dakshinamurthy, R, Thallapuranam, S.K.K, Sakon, J.
登録日2008-10-24
公開日2009-10-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Cystal structure of synaptotagmin I C2A
to be published
3FDW
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Crystal structure of a C2 domain from human synaptotagmin-like protein 4
分子名称: Synaptotagmin-like protein 4
著者Bonanno, J.B, Rutter, M, Bain, K.T, Miller, S, Romero, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-11-26
公開日2008-12-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a C2 domain from human synaptotagmin-like protein 4
To be Published
3F00
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Crystal Structure of Synaptotagmin I C2A domain with Cu(II)
分子名称: COPPER (II) ION, SULFATE ION, Synaptotagmin-1
著者Guo, F, Dakshinamurthy, R, Thallapuranam, S.K.K, Sakon, J.
登録日2008-10-24
公開日2009-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Crystal structure of Synaptotagmin I C2A
To be Published

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