7MLL
 
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1NAU
 | | NMR Solution Structure of the Glucagon Antagonist [desHis1, desPhe6, Glu9]Glucagon Amide in the Presence of Perdeuterated Dodecylphosphocholine Micelles | | 分子名称: | Glucagon | | 著者 | Ying, J, Ahn, J.-M, Jacobsen, N.E, Brown, M.F, Hruby, V.J. | | 登録日 | 2002-11-28 | | 公開日 | 2003-03-18 | | 最終更新日 | 2021-10-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Solution Structure of the Glucagon Antagonist [desHis1, desPhe6, Glu9]Glucagon Amide in the Presence of Perdeuterated Dodecylphosphocholine Micelles
Biochemistry, 42, 2003
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8GJI
 | | De novo design of high-affinity protein binders to bioactive helical peptides | | 分子名称: | GCG binder, Glucagon | | 著者 | Torres, S.V, Leung, P.J.Y, Bera, A.K, Baker, D, Kang, A. | | 登録日 | 2023-03-15 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | De novo design of high-affinity binders of bioactive helical peptides.
Nature, 626, 2024
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4APD
 | | Liraglutide | | 分子名称: | LIRAGLUTIDE, N-hexadecanoyl-L-glutamic acid | | 著者 | Ludvigsen, S, Steensgaard, D.B, Thomsen, J.K, Strauss, H, Normann, M. | | 登録日 | 2012-04-02 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Liraglutide
To be Published
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5NIQ
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1T5Q
 | | Solution Structure of GIP(1-30)amide in TFE/Water | | 分子名称: | Gastric inhibitory polypeptide | | 著者 | Alana, I, Hewage, C.M, Malthouse, J.P.G, Parker, J.C, Gault, V.A, O'Harte, F.P.M. | | 登録日 | 2004-05-05 | | 公開日 | 2004-11-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the glucose-dependent insulinotropic polypeptide fragment, GIP(1-30)amide.
Biochem.Biophys.Res.Commun., 325, 2004
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2D2P
 | | The solution structure of micelle-bound peptide | | 分子名称: | Pituitary adenylate cyclase activating polypeptide-38 | | 著者 | Tateishi, Y, Jee, J.G, Inooka, H, Tochio, H, Hiroaki, H, Shirakawa, M. | | 登録日 | 2005-09-14 | | 公開日 | 2006-09-26 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of micelle-bound peptide
To be Published
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2RRI
 | | NMR structure of vasoactive intestinal peptide in DPC Micelle | | 分子名称: | Vasoactive intestinal peptide | | 著者 | Umetsu, Y, Tenno, T, Goda, N, Shirakawa, M, Ikegami, T, Hiroaki, H. | | 登録日 | 2010-12-21 | | 公開日 | 2011-04-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural difference of vasoactive intestinal peptide in two distinct membrane-mimicking environments
Biochim.Biophys.Acta, 1814, 2011
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2RRH
 | | NMR structure of vasoactive intestinal peptide in Methanol | | 分子名称: | VIP peptides | | 著者 | Umetsu, Y, Tenno, T, Goda, N, Ikegami, T, Hiroaki, H. | | 登録日 | 2010-11-12 | | 公開日 | 2011-04-06 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural difference of vasoactive intestinal peptide in two distinct membrane-mimicking environments.
Biochim.Biophys.Acta, 1814, 2011
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1GEA
 | | RECEPTOR-BOUND CONFORMATION OF PACAP21 | | 分子名称: | PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE | | 著者 | Inooka, H, Ohtaki, T, Kitahara, O, Ikegami, T, Endo, S, Kitada, C, Ogi, K, Onda, H, Fujino, M, Shirakawa, M. | | 登録日 | 2000-10-20 | | 公開日 | 2001-04-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conformation of a peptide ligand bound to its G-protein coupled receptor.
Nat.Struct.Biol., 8, 2001
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1KX6
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1JRJ
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1GCN
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1D0R
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6GDZ
 | | exendin-4 based dual GLP-1/glucagon receptor agonist | | 分子名称: | (2~{S})-2-[[(4~{S})-4-(hexadecanoylamino)-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]pentanedioic acid, Exendin-4 | | 著者 | Evers, A, Kurz, M. | | 登録日 | 2018-04-25 | | 公開日 | 2018-06-20 | | 最終更新日 | 2019-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations.
J. Med. Chem., 61, 2018
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6GE2
 | | exendin-4 based dual GLP-1/glucagon receptor agonist | | 分子名称: | (2~{S})-2-[[(4~{S})-4-(hexadecanoylamino)-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]pentanedioic acid, Exendin-4 | | 著者 | Evers, A, Kurz, M. | | 登録日 | 2018-04-25 | | 公開日 | 2018-06-20 | | 最終更新日 | 2019-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations.
J. Med. Chem., 61, 2018
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6NZN
 | | Dimer-of-dimer amyloid fibril structure of glucagon | | 分子名称: | Glucagon | | 著者 | Gelenter, M.D, Smith, K.J, Liao, S.Y, Mandala, V.S, Dregni, A.J, Lamm, M.S, Tian, Y, Wei, X, Pochan, D.J, Tucker, T.J, Su, Y, Hong, M. | | 登録日 | 2019-02-14 | | 公開日 | 2019-06-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | The peptide hormone glucagon forms amyloid fibrils with two coexisting beta-strand conformations.
Nat.Struct.Mol.Biol., 26, 2019
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2B4N
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1BH0
 | | STRUCTURE OF A GLUCAGON ANALOG | | 分子名称: | GLUCAGON | | 著者 | Sturm, N.S, Lin, Y, Burley, S.K, Krstenansky, J.L, Ahn, J.-M, Azizeh, B.Y, Trivedi, D, Hruby, V.J. | | 登録日 | 1998-06-11 | | 公開日 | 1998-11-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure-function studies on positions 17, 18, and 21 replacement analogues of glucagon: the importance of charged residues and salt bridges in glucagon biological activity.
J.Med.Chem., 41, 1998
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7XM8
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2MJ9
 | | Designed Exendin-4 analogues | | 分子名称: | Exendin-4 | | 著者 | Rovo, P, Farkas, V, Straner, P, Szabo, M, Jermendy, A, Hegyi, O, Toth, G.K, Perczel, A. | | 登録日 | 2013-12-30 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Rational design of alpha-helix-stabilized exendin-4 analogues.
Biochemistry, 53, 2014
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2M5Q
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2OBU
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2L64
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2L63
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