6NZN
Dimer-of-dimer amyloid fibril structure of glucagon
Summary for 6NZN
Entry DOI | 10.2210/pdb6nzn/pdb |
NMR Information | BMRB: 30572 |
Descriptor | Glucagon (1 entity in total) |
Functional Keywords | amyloid, hormone, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 16 |
Total formula weight | 55788.50 |
Authors | Gelenter, M.D.,Smith, K.J.,Liao, S.Y.,Mandala, V.S.,Dregni, A.J.,Lamm, M.S.,Tian, Y.,Wei, X.,Pochan, D.J.,Tucker, T.J.,Su, Y.,Hong, M. (deposition date: 2019-02-14, release date: 2019-06-05, Last modification date: 2023-06-14) |
Primary citation | Gelenter, M.D.,Smith, K.J.,Liao, S.Y.,Mandala, V.S.,Dregni, A.J.,Lamm, M.S.,Tian, Y.,Xu, W.,Pochan, D.J.,Tucker, T.J.,Su, Y.,Hong, M. The peptide hormone glucagon forms amyloid fibrils with two coexisting beta-strand conformations. Nat.Struct.Mol.Biol., 26:592-598, 2019 Cited by PubMed: 31235909DOI: 10.1038/s41594-019-0238-6 PDB entries with the same primary citation |
Experimental method | SOLID-STATE NMR |
Structure validation
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