Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 663 件
7YSV
DownloadVisualize
BU of 7ysv by Molmil
GluK1-1a extracellular domain captured in SYM2081 bound desensitized state
分子名称: Glutamate receptor
著者Dhingra, S, Kumar, J.
登録日2022-08-13
公開日2023-08-16
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (8.01 Å)
主引用文献Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors
Elife, 2023
7YSJ
DownloadVisualize
BU of 7ysj by Molmil
GluK1-1a in nanodisc captured in SYM2081 bound desensitized state
分子名称: Glutamate receptor
著者Dhingra, S, Kumar, J.
登録日2022-08-12
公開日2023-08-16
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors
Elife, 2023
6FQI
DownloadVisualize
BU of 6fqi by Molmil
GluA2(flop) G724C ligand binding core dimer bound to L-Glutamate (Form B) at 2.91 Angstrom resolution
分子名称: GLUTAMIC ACID, Glutamate receptor 2
著者Coombs, I.D, Soto, D, Gold, M.G, Farrant, M.F, Cull-Candy, S.G.
登録日2018-02-14
公開日2019-03-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.91001153 Å)
主引用文献Homomeric GluA2(R) AMPA receptors can conduct when desensitized.
Nat Commun, 10, 2019
6FQK
DownloadVisualize
BU of 6fqk by Molmil
GluA2(flop) S729C ligand binding core dimer bound to ZK200775 at 1.98 Angstrom resolution
分子名称: Glutamate receptor 2,Glutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
著者Coombs, I.D, Soto, D, Gold, M.G, Farrant, M.F, Cull-Candy, S.G.
登録日2018-02-14
公開日2019-03-13
最終更新日2019-10-02
実験手法X-RAY DIFFRACTION (1.98010445 Å)
主引用文献Homomeric GluA2(R) AMPA receptors can conduct when desensitized.
Nat Commun, 10, 2019
6FQJ
DownloadVisualize
BU of 6fqj by Molmil
GluA2(flop) G724C ligand binding core dimer bound to ZK200775 at 2.50 Angstrom resolution
分子名称: Glutamate receptor 2,Glutamate receptor 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
著者Coombs, I.D, Soto, D, Gold, M.G, Farrant, M.F, Cull-Candy, S.G.
登録日2018-02-14
公開日2019-03-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.500017 Å)
主引用文献Homomeric GluA2(R) AMPA receptors can conduct when desensitized.
Nat Commun, 10, 2019
6FQG
DownloadVisualize
BU of 6fqg by Molmil
GluA2(flop) G724C ligand binding core dimer bound to L-Glutamate (Form A) at 2.34 Angstrom resolution
分子名称: GLUTAMIC ACID, Glutamate receptor 2
著者Coombs, I.D, Soto, D, Gold, M.G, Farrant, M.F, Cull-Candy, S.G.
登録日2018-02-14
公開日2019-03-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.34139085 Å)
主引用文献X-ray structure of GluA2 flop G724C ligand binding core dimer bound to glutamate at 2.32 Angstroms resolution
To Be Published
1P1N
DownloadVisualize
BU of 1p1n by Molmil
GluR2 Ligand Binding Core (S1S2J) Mutant L650T in Complex with Kainate
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2
著者Armstrong, N, Mayer, M.L, Gouaux, E.
登録日2003-04-13
公開日2003-06-10
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1PB8
DownloadVisualize
BU of 1pb8 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-SERINE AT 1.45 ANGSTROMS RESOLUTION
分子名称: D-SERINE, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-06-24
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PB9
DownloadVisualize
BU of 1pb9 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-CYCLOSERINE AT 1.60 ANGSTROMS RESOLUTION
分子名称: (R)-4-AMINO-ISOXAZOLIDIN-3-ONE, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-06-24
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
1PBQ
DownloadVisualize
BU of 1pbq by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH 5,7-DICHLOROKYNURENIC ACID (DCKA) AT 1.90 ANGSTROMS RESOLUTION
分子名称: 5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-07-29
最終更新日2020-07-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
8SS4
DownloadVisualize
BU of 8ss4 by Molmil
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 (apo state)
分子名称: Glutamate receptor 2, Voltage-dependent calcium channel gamma-5 subunit chimera, Protein cornichon homolog 2, ...
著者Yen, L.Y, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2023-05-08
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SS8
DownloadVisualize
BU of 8ss8 by Molmil
Structure of AMPA receptor GluA2 complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, CHOLESTEROL, ...
著者Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2023-05-08
公開日2023-09-06
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SS5
DownloadVisualize
BU of 8ss5 by Molmil
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 (apo state)
分子名称: Glutamate receptor 2, Voltage-dependent calcium channel gamma-5 subunit chimera, SODIUM ION
著者Yen, L.Y, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2023-05-08
公開日2023-09-06
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SSA
DownloadVisualize
BU of 8ssa by Molmil
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2, ...
著者Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2023-05-08
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SSB
DownloadVisualize
BU of 8ssb by Molmil
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine (desensitized state)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2, ...
著者Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2023-05-08
公開日2023-09-06
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SS7
DownloadVisualize
BU of 8ss7 by Molmil
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel (closed state)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, CHOLESTEROL, ...
著者Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2023-05-08
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SS3
DownloadVisualize
BU of 8ss3 by Molmil
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, Digitonin, ...
著者Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2023-05-08
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SS2
DownloadVisualize
BU of 8ss2 by Molmil
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, Digitonin, ...
著者Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2023-05-08
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SS9
DownloadVisualize
BU of 8ss9 by Molmil
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, CHOLESTEROL, ...
著者Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2023-05-08
公開日2023-09-06
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
8SS6
DownloadVisualize
BU of 8ss6 by Molmil
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel (closed state)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, CHOLESTEROL, ...
著者Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2023-05-08
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2.
Nat.Struct.Mol.Biol., 30, 2023
1PB7
DownloadVisualize
BU of 1pb7 by Molmil
CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH GLYCINE AT 1.35 ANGSTROMS RESOLUTION
分子名称: GLYCINE, N-methyl-D-aspartate Receptor Subunit 1
著者Furukawa, H, Gouaux, E.
登録日2003-05-14
公開日2003-06-24
最終更新日2017-07-26
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core
Embo J., 22, 2003
8JF7
DownloadVisualize
BU of 8jf7 by Molmil
Triheteromeric NMDA receptor GluN1-GluN2A-GluN3A in complex with glycine, glutamate, a GluN1-specific Fab,and a GluN2A-specific Fab
分子名称: GluN1-specific antibody fragment heavy chain, GluN1-specific antibody fragment light chain, GluN2A-specific antibody fragment heavy chain, ...
著者Kou, Z, Zhu, S.
登録日2023-05-17
公開日2024-05-22
実験手法ELECTRON MICROSCOPY (7.73 Å)
主引用文献Probing the architecture of native GluN1-N2-N3A NMDA receptors by cryo-EM and click chemistry.
To Be Published
2PBW
DownloadVisualize
BU of 2pbw by Molmil
Crystal Structure of the Ligand-Binding Core of iGluR5 in Complex with the Partial agonist Domoic Acid at 2.5 A Resolution
分子名称: (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, Glutamate receptor, ionotropic kainate 1
著者Hald, H, Naur, P, Gajhede, M, Kastrup, J.S.
登録日2007-03-29
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.
J.Biol.Chem., 282, 2007
2OJT
DownloadVisualize
BU of 2ojt by Molmil
Structure and mechanism of kainate receptor modulation by anions
分子名称: (S)-1-(2-AMINO-2-CARBOXYETHYL)-3(2-CARBOXYTHIOPHENE-3-YL-METHYL)-5-METHYLPYRIMIDINE-2,4-DIONE, BROMIDE ION, Glutamate receptor, ...
著者Mayer, M.L.
登録日2007-01-14
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and mechanism of kainate receptor modulation by anions.
Neuron, 53, 2007
1NNK
DownloadVisualize
BU of 1nnk by Molmil
X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-ATPA at 1.85 A resolution. Crystallization with zinc ions.
分子名称: 3-(5-TERT-BUTYL-3-OXIDOISOXAZOL-4-YL)-L-ALANINATE, CHLORIDE ION, Glutamate receptor 2, ...
著者Lunn, M.-L, Hogner, A, Stensbol, T.B, Gouaux, E, Egebjerg, J, Kastrup, J.S.
登録日2003-01-14
公開日2003-03-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Three-Dimensional Structure of the Ligand-Binding Core of GluR2 in Complex with the Agonist (S)-ATPA: Implications for Receptor Subunit Selectivity.
J.Med.Chem., 46, 2003

221371

件を2024-06-19に公開中

PDB statisticsPDBj update infoContact PDBjnumon