1P1W
Crystal structure of the GluR2 ligand-binding core (S1S2J) with the L483Y and L650T mutations and in complex with AMPA
Summary for 1P1W
Entry DOI | 10.2210/pdb1p1w/pdb |
Related | 1P1N 1P1O 1P1Q 1P1U |
Descriptor | Glutamate receptor 2 precursor, SULFATE ION, (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, ... (4 entities in total) |
Functional Keywords | ionotropic glutamate receptor, ampa receptor, ion channel, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 2 |
Total formula weight | 59083.75 |
Authors | Armstrong, N.,Mayer, M.L.,Gouaux, E. (deposition date: 2003-04-14, release date: 2003-06-10, Last modification date: 2021-10-27) |
Primary citation | Armstrong, N.,Mayer, M.,Gouaux, E. Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes. Proc.Natl.Acad.Sci.USA, 100:5736-5741, 2003 Cited by PubMed: 12730367DOI: 10.1073/pnas.1037393100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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