1P1W
Crystal structure of the GluR2 ligand-binding core (S1S2J) with the L483Y and L650T mutations and in complex with AMPA
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Glutamate receptor 2 precursor | polymer | 263 | 29259.6 | 2 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) Pfam (PF00497) In PDB | Rattus norvegicus (Norway rat) | GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2 |
2 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
3 | A, B | (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID | non-polymer | 186.2 | 2 | Chemie (AMQ) | |||
4 | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 117 (UniProt: P19491)
A, B: 120 - 263 (UniProt: P19491)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | cloning artifact |
Ala 2 | - | cloning artifact |
Tyr 94 | Leu 504 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 118 | - | insertion |
Thr 119 | - | insertion |
Thr 138 | Leu 672 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 58519.3 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 564.5 | |
All* | Total formula weight | 59083.7 |