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PDB: 666 件
6UGF
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BU of 6ugf by Molmil
Katanin hexamer in the ring conformation with resolved protomer one in complex with substrate
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Meiotic spindle formation protein mei-1, ...
著者Zehr, E.A, Roll-Mecak, A.
登録日2019-09-26
公開日2019-10-09
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Katanin Grips the beta-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules.
Dev.Cell, 52, 2020
6UQE
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BU of 6uqe by Molmil
ClpA/ClpP Disengaged State bound to RepA-GFP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ATP-dependent Clp protease proteolytic subunit, ...
著者Lopez, K.L, Rizo, A.R, Southworth, D.R.
登録日2019-10-18
公開日2020-04-22
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
6V11
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BU of 6v11 by Molmil
Lon Protease from Yersinia pestis
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease
著者Shin, M, Puchades, C, Asmita, A, Puri, N, Adjei, E, Wiseman, R.L, Karzai, A.W, Lander, G.C.
登録日2019-11-19
公開日2020-01-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis for distinct operational modes and protease activation in AAA+ protease Lon.
Sci Adv, 6, 2020
6UQO
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BU of 6uqo by Molmil
ClpA/ClpP Engaged State bound to RepA-GFP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp endopeptidase proteolytic subunit ClpP, ATP-dependent Clp protease ATP-binding subunit ClpA, ...
著者Lopez, K.L, Rizo, A.N, Southworth, D.R.
登録日2019-10-21
公開日2020-04-22
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
7MDM
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BU of 7mdm by Molmil
Structure of human p97 ATPase L464P mutant
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F.
登録日2021-04-05
公開日2021-08-25
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.86 Å)
主引用文献Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity.
Biochem.J., 478, 2021
7MDO
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BU of 7mdo by Molmil
Structure of human p97 ATPase L464P mutant
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Zhang, X, Gui, L, Li, S, Nandi, P, Columbres, R.C, Wong, D.E, Moen, D.R, Lin, H.J, Chiu, P.-L, Chou, T.-F.
登録日2021-04-05
公開日2021-08-25
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.12 Å)
主引用文献Conserved L464 in p97 D1-D2 linker is critical for p97 cofactor regulated ATPase activity.
Biochem.J., 478, 2021
7MHS
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BU of 7mhs by Molmil
Structure of p97 (subunits A to E) with substrate engaged
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
著者Xu, Y, Han, H, Cooney, I, Hill, C.P, Shen, P.S.
登録日2021-04-15
公開日2022-05-11
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Active conformation of the p97-p47 unfoldase complex.
Nat Commun, 13, 2022
7NFY
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BU of 7nfy by Molmil
P1a-state of wild type human mitochondrial LONP1 protease with bound substrate protein and ATPgS
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial, ...
著者Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
登録日2021-02-08
公開日2021-02-24
最終更新日2022-11-09
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NG5
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BU of 7ng5 by Molmil
P1c-state of wild type human mitochondrial LONP1 protease with bound substrate protein in presence of ATP/ADP mix
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
著者Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
登録日2021-02-08
公開日2021-02-24
最終更新日2022-11-09
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NG4
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BU of 7ng4 by Molmil
P1b-state of wild type human mitochondrial LONP1 protease with bound endogenous substrate protein and in presence of ATP/ADP mix
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
著者Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
登録日2021-02-08
公開日2021-02-24
最終更新日2022-11-09
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
6W20
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BU of 6w20 by Molmil
ClpAP Disengaged State bound to RepA-GFP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ...
著者Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R.
登録日2020-03-04
公開日2020-05-06
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
6W1Z
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BU of 6w1z by Molmil
ClpAP Engaged1 State bound to RepA-GFP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ...
著者Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R.
登録日2020-03-04
公開日2020-05-06
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
6W23
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BU of 6w23 by Molmil
ClpA Disengaged State bound to RepA-GFP (Focused Classification)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ...
著者Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R.
登録日2020-03-04
公開日2020-05-06
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
7MHB
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BU of 7mhb by Molmil
Crystal structure of ATP-dependent protease ATPase subunit HslU in complex with Adenosine 5'-diphosphate
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-04-15
公開日2021-04-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of ATP-dependent protease ATPase subunit HslU in complex with Adenosine 5'-diphosphate
to be published
6W24
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BU of 6w24 by Molmil
ClpA Engaged2 State bound to RepA-GFP (Focused Classification)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ...
著者Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R.
登録日2020-03-04
公開日2020-05-06
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
6W6G
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BU of 6w6g by Molmil
The Mycobacterium tuberculosis ClpB disaggregase hexamer structure in conformation I in the presence of DnaK chaperone and a model substrate
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Yin, Y, Li, H.
登録日2020-03-16
公開日2021-03-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
Cell Rep, 35, 2021
7NGC
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BU of 7ngc by Molmil
P2a-state of wild type human mitochondrial LONP1 protease with bound substrate protein and in presence of ATPgS
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial, ...
著者Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
登録日2021-02-09
公開日2021-04-07
最終更新日2022-11-09
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NGQ
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BU of 7ngq by Molmil
Human mitochondrial Lon protease homolog, D2-state
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
著者Mohammed, I, Abrahams, J.P, Schmitz, K.A, Maier, T, Schenck, N.
登録日2021-02-09
公開日2021-04-28
最終更新日2022-11-09
実験手法ELECTRON MICROSCOPY (12 Å)
主引用文献Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NGF
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BU of 7ngf by Molmil
P2c-state of wild type human mitochondrial LONP1 protease with bound endogenous substrate protein and in presence of ATP/ADP mix
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ...
著者Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
登録日2021-02-09
公開日2021-04-28
最終更新日2022-11-09
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
6W21
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BU of 6w21 by Molmil
ClpAP Engaged2 State bound to RepA-GFP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpA, ...
著者Lopez, K.L, Rizo, A.N, Tse, E, Lin, J, Scull, N.W, Thwin, A.C, Lucius, A.L, Shorter, J, Southworth, D.R.
登録日2020-03-04
公開日2020-05-13
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis.
Nat.Struct.Mol.Biol., 27, 2020
7NGP
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BU of 7ngp by Molmil
D1-state of wild type human mitochondrial LONP1 protease
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
著者Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
登録日2021-02-09
公開日2021-04-28
最終更新日2022-11-09
実験手法ELECTRON MICROSCOPY (15 Å)
主引用文献Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7NGL
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BU of 7ngl by Molmil
R-state of wild type human mitochondrial LONP1 protease bound to endogenous ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
著者Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T, Abrahams, J.P.
登録日2021-02-09
公開日2021-04-28
最終更新日2022-11-09
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Catalytic cycling of human mitochondrial Lon protease.
Structure, 30, 2022
7MCA
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BU of 7mca by Molmil
Structure of the S. cerevisiae origin recognition complex bound to the replication initiator Cdc6 and the ARS1 origin DNA.
分子名称: Cell division control protein 6, DNA (85-MER), MAGNESIUM ION, ...
著者Feng, X, Li, H.
登録日2021-04-01
公開日2021-06-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.
Nat Commun, 12, 2021
6WJD
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BU of 6wjd by Molmil
SA-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Chen, X, Walters, K.J.
登録日2020-04-13
公開日2020-08-05
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
Structure, 28, 2020
6VVO
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BU of 6vvo by Molmil
Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen, PCNA)
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Gaubitz, C, Liu, X, Stone, N.P, Kelch, B.A.
登録日2020-02-18
公開日2020-02-26
最終更新日2020-03-25
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism
Biorxiv, 2020

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件を2024-06-12に公開中

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