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PDB: 19 件
8DVP
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BU of 8dvp by Molmil
Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with substrate purine
分子名称: ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ...
著者Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S.
登録日2022-07-29
公開日2022-11-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
8DW0
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BU of 8dw0 by Molmil
Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an enzyme-generated abasic site (AP) product and crystallized with sodium acetate
分子名称: 1,2-ETHANEDIOL, Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), ...
著者Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S.
登録日2022-07-30
公開日2022-11-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
8DWD
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BU of 8dwd by Molmil
Adenine glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with an AP site generated by the enzyme acting on purine
分子名称: ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ...
著者Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P.
登録日2022-08-01
公開日2023-08-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY
To Be Published
5KN8
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BU of 5kn8 by Molmil
MutY N-terminal domain in complex with undamaged DNA
分子名称: Adenine DNA glycosylase, CALCIUM ION, DNA (5'-D(*AP*GP*CP*AP*CP*AP*GP*GP*AP*T)-3'), ...
著者Wang, L, Chakravarthy, S, Verdine, G.L.
登録日2016-06-27
公開日2017-02-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase.
J. Biol. Chem., 292, 2017
5KN9
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BU of 5kn9 by Molmil
MutY N-terminal domain in complex with DNA containing an intrahelical oxoG:A base-pair
分子名称: Adenine DNA glycosylase, CALCIUM ION, DNA (5'-D(*AP*GP*CP*AP*CP*AP*GP*GP*AP*T)-3'), ...
著者Wang, L, Chakravarthy, S, Verdine, G.L.
登録日2016-06-27
公開日2017-02-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural Basis for the Lesion-scanning Mechanism of the MutY DNA Glycosylase.
J. Biol. Chem., 292, 2017
8DW7
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BU of 8dw7 by Molmil
DNA glycosylase MutY variant N146S in complex with DNA containing the transition state analog 1N paired with d(8-oxo-G)
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Adenine DNA glycosylase, ...
著者Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S.
登録日2022-07-31
公開日2022-11-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
6U7T
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BU of 6u7t by Molmil
MutY adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G)
分子名称: Adenine DNA glycosylase, CALCIUM ION, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), ...
著者O'Shea Murray, V.L, Cao, S, Horvath, M.P, David, S.S.
登録日2019-09-03
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY.
Acs Chem.Biol., 15, 2020
6Q0C
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BU of 6q0c by Molmil
MutY adenine glycosylase bound to DNA containing a transition state analog (1N) paired with undamaged dG
分子名称: 1,2-ETHANEDIOL, A/G-specific adenine glycosylase, CALCIUM ION, ...
著者O'Shea Murray, V.L, Russelburg, L.P, Horvath, M.P, David, S.S.
登録日2019-08-01
公開日2019-08-28
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY.
Acs Chem.Biol., 15, 2020
8DWE
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BU of 8dwe by Molmil
Adenine glycosylase MutY variant E43Q in complex with DNA containing d(8-oxo-G) paired with substrate purine
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Adenine DNA glycosylase, ...
著者Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P.
登録日2022-08-01
公開日2023-08-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY
To Be Published
3G0Q
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BU of 3g0q by Molmil
Crystal Structure of MutY bound to its inhibitor DNA
分子名称: 5'-D(*AP*AP*GP*AP*CP*(8OG)P*GP*GP*GP*AP*C)-3', 5'-D(*GP*TP*CP*CP*CP*AP*GP*TP*CP*TP*T)-3', A/G-specific adenine glycosylase, ...
著者Lee, S, Verdine, G.L.
登録日2009-01-28
公開日2009-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase.
Proc.Natl.Acad.Sci.Usa, 106, 2009
4YOQ
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BU of 4yoq by Molmil
Crystal Structure of MutY bound to its anti-substrate
分子名称: A/G-specific adenine glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(*T*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3'), ...
著者Wang, L, Lee, S, Verdine, G.L.
登録日2015-03-11
公開日2015-05-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase.
J.Biol.Chem., 290, 2015
1RRQ
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BU of 1rrq by Molmil
MutY adenine glycosylase in complex with DNA containing an A:oxoG pair
分子名称: 5'-D(*TP*GP*TP*CP*CP*AP*AP*GP*TP*CP*T)-3', 5'-D(AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3', CALCIUM ION, ...
著者Fromme, J.C, Banerjee, A, Huang, S.J, Verdine, G.L.
登録日2003-12-08
公開日2004-02-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase
Nature, 427, 2004
4YPH
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BU of 4yph by Molmil
Crystal Structure of MutY bound to its anti-substrate with the disulfide cross-linker reduced
分子名称: A/G-specific adenine glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(TP*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3'), ...
著者Wang, L, Lee, S, Verdine, G.L.
登録日2015-03-12
公開日2015-05-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase.
J.Biol.Chem., 290, 2015
8DVY
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BU of 8dvy by Molmil
DNA glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an enzyme-generated abasic site product (AP) and crystalized with calcium acetate
分子名称: ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ...
著者Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S.
登録日2022-07-30
公開日2022-11-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
1RRS
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BU of 1rrs by Molmil
MutY adenine glycosylase in complex with DNA containing an abasic site
分子名称: 5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3', 5'-D(*TP*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*T)-3', CALCIUM ION, ...
著者Fromme, J.C, Banerjee, A, Huang, S.J, Verdine, G.L.
登録日2003-12-08
公開日2004-02-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase
Nature, 427, 2004
8DW4
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BU of 8dw4 by Molmil
Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an abasic site product (AP) generated by the enzyme in crystals by removal of calcium
分子名称: ACETATE ION, Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), ...
著者Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S.
登録日2022-07-31
公開日2022-11-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
1VRL
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BU of 1vrl by Molmil
MutY adenine glycosylase in complex with DNA and soaked adenine free base
分子名称: 5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3', 5'-D(*TP*GP*TP*CP*CP*AP*(HPD)P*GP*TP*CP*T)-3', ADENINE, ...
著者Fromme, J.C, Banerjee, A, Huang, S.J, Verdine, G.L.
登録日2005-03-08
公開日2005-03-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase
Nature, 427, 2004
4YPR
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BU of 4ypr by Molmil
Crystal Structure of D144N MutY bound to its anti-substrate
分子名称: A/G-specific adenine glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(*T*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3'), ...
著者Wang, L, Lee, S, Verdine, G.L.
登録日2015-03-13
公開日2015-05-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase.
J.Biol.Chem., 290, 2015
8DWF
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BU of 8dwf by Molmil
Glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with substrate adenine
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Adenine DNA glycosylase, ...
著者Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P.
登録日2022-08-01
公開日2023-08-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY
To Be Published

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件を2024-07-10に公開中

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