5XLV
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![BU of 5xlv by Molmil](/molmil-images/mine/5xlv) | Mycobacterium tuberculosis Pantothenate kinase mutant F254A | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Pantothenate kinase, ... | 著者 | Paul, A, Kumar, P, Surolia, A, Vijayan, M. | 登録日 | 2017-05-11 | 公開日 | 2018-05-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Biochemical and structural studies of mutants indicate concerted movement of the dimer interface and ligand-binding region of Mycobacterium tuberculosis pantothenate kinase Acta Crystallogr F Struct Biol Commun, 73, 2017
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4BFZ
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3AEZ
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![BU of 3aez by Molmil](/molmil-images/mine/3aez) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with GDP and Phosphopantothenate | 分子名称: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanine, ... | 著者 | Chetnani, B, Kumar, P, Surolia, A, Vijayan, M. | 登録日 | 2010-02-18 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | M. tuberculosis pantothenate kinase: dual substrate specificity and unusual changes in ligand locations J.Mol.Biol., 400, 2010
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5XLW
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![BU of 5xlw by Molmil](/molmil-images/mine/5xlw) | Mycobacterium tuberculosis Pantothenate kinase mutant F247A/F254A | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PENTAETHYLENE GLYCOL, ... | 著者 | Paul, A, Kumar, P, Surolia, A, Vijayan, M. | 登録日 | 2017-05-11 | 公開日 | 2018-05-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Biochemical and structural studies of mutants indicate concerted movement of the dimer interface and ligand-binding region of Mycobacterium tuberculosis pantothenate kinase Acta Crystallogr F Struct Biol Commun, 73, 2017
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4BFW
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![BU of 4bfw by Molmil](/molmil-images/mine/4bfw) | Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1e) and phosphate | 分子名称: | N-[1-(5-{[2-(4-fluorophenoxy)ethyl]sulfanyl}-4-[(4-fluorophenyl)methyl]-4H-1,2,4-triazol-3-yl)ethyl]-2-(trifluoromethyl)benzamide, PANTOTHENATE KINASE, PHOSPHATE ION | 著者 | Bjorkelid, C, Bergfors, T, Jones, T.A. | 登録日 | 2013-03-22 | 公開日 | 2013-05-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
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4BFU
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![BU of 4bfu by Molmil](/molmil-images/mine/4bfu) | Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1c) and phosphate | 分子名称: | N-[1-(5-{[(4-fluorophenyl)methyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)ethyl]-2-(trifluoromethyl)benzamide, PANTOTHENATE KINASE, PHOSPHATE ION | 著者 | Bjorkelid, C, Bergfors, T, Jones, T.A. | 登録日 | 2013-03-22 | 公開日 | 2013-05-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
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4BFT
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![BU of 4bft by Molmil](/molmil-images/mine/4bft) | Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1b) and phosphate | 分子名称: | 2-chloro-N-[1-(5-{[2-(4-fluorophenoxy)ethyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)ethyl]benzamide, PANTOTHENATE KINASE, PHOSPHATE ION | 著者 | Bjorkelid, C, Bergfors, T, Jones, T.A. | 登録日 | 2013-03-22 | 公開日 | 2013-05-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
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4BFV
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![BU of 4bfv by Molmil](/molmil-images/mine/4bfv) | Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1d) and phosphate | 分子名称: | N-[1-(4-methyl-5-{[2-(2-methylphenoxy)ethyl]sulfanyl}-4H-1,2,4-triazol-3-yl)ethyl]-2-(trifluoromethyl)benzamide, PANTOTHENATE KINASE, PHOSPHATE ION | 著者 | Bjorkelid, C, Bergfors, T, Jones, T.A. | 登録日 | 2013-03-22 | 公開日 | 2013-05-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
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4BFY
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3AF2
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![BU of 3af2 by Molmil](/molmil-images/mine/3af2) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with AMPPCP | 分子名称: | GLYCEROL, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Pantothenate kinase | 著者 | Chetnani, B, Kumar, P, Surolia, A, Vijayan, M. | 登録日 | 2010-02-22 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | M. tuberculosis pantothenate kinase: dual substrate specificity and unusual changes in ligand locations J.Mol.Biol., 400, 2010
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2GET
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![BU of 2get by Molmil](/molmil-images/mine/2get) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with a coenzyme A derivative, Form-I (LT) | 分子名称: | GLYCEROL, Pantothenate kinase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-3-HYDROXY-4-{[3-({2-[(2-HYDROXYETHYL)DITHIO]ETHYL}AMINO)-3-OXOPROPYL]AMINO}-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE | 著者 | Das, S, Kumar, P, Bhor, V, Surolia, A, Vijayan, M. | 登録日 | 2006-03-20 | 公開日 | 2006-06-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK. Acta Crystallogr.,Sect.D, 62, 2006
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2GEV
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![BU of 2gev by Molmil](/molmil-images/mine/2gev) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with a coenzyme A derivative, Form-II (LT) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Pantothenate kinase, ... | 著者 | Das, S, Kumar, P, Bhor, V, Surolia, A, Vijayan, M. | 登録日 | 2006-03-20 | 公開日 | 2006-06-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK. Acta Crystallogr.,Sect.D, 62, 2006
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3AF3
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![BU of 3af3 by Molmil](/molmil-images/mine/3af3) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with GMPPCP and Pantothenate | 分子名称: | GLYCEROL, PANTOTHENOIC ACID, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | 著者 | Chetnani, B, Kumar, P, Surolia, A, Vijayan, M. | 登録日 | 2010-02-22 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | M. tuberculosis pantothenate kinase: dual substrate specificity and unusual changes in ligand locations J.Mol.Biol., 400, 2010
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2GES
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![BU of 2ges by Molmil](/molmil-images/mine/2ges) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with a coenzyme A derivative, Form-I (RT) | 分子名称: | Pantothenate kinase, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-3-HYDROXY-4-{[3-({2-[(2-HYDROXYETHYL)DITHIO]ETHYL}AMINO)-3-OXOPROPYL]AMINO}-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE | 著者 | Das, S, Kumar, P, Bhor, V, Surolia, A, Vijayan, M. | 登録日 | 2006-03-20 | 公開日 | 2006-06-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK. Acta Crystallogr.,Sect.D, 62, 2006
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2ZSA
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![BU of 2zsa by Molmil](/molmil-images/mine/2zsa) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with ADP and Phosphopantothenate | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | 著者 | Chetnani, B, Das, S, Kumar, P, Surolia, A, Vijayan, M. | 登録日 | 2008-09-04 | 公開日 | 2009-07-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action Acta Crystallogr.,Sect.D, 65, 2009
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3AF0
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![BU of 3af0 by Molmil](/molmil-images/mine/3af0) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with GDP and Pantothenate | 分子名称: | CHLORIDE ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Chetnani, B, Kumar, P, Surolia, A, Vijayan, M. | 登録日 | 2010-02-19 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | M. tuberculosis pantothenate kinase: dual substrate specificity and unusual changes in ligand locations J.Mol.Biol., 400, 2010
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2ZSE
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![BU of 2zse by Molmil](/molmil-images/mine/2zse) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with AMPPCP and Pantothenate | 分子名称: | 1,2-ETHANEDIOL, CITRATE ANION, GLYCEROL, ... | 著者 | Chetnani, B, Das, S, Kumar, P, Surolia, A, Vijayan, M. | 登録日 | 2008-09-05 | 公開日 | 2009-07-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action Acta Crystallogr.,Sect.D, 65, 2009
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2ZSD
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![BU of 2zsd by Molmil](/molmil-images/mine/2zsd) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with Coenzyme A | 分子名称: | 1,2-ETHANEDIOL, COENZYME A, GLYCEROL, ... | 著者 | Chetnani, B, Das, S, Kumar, P, Surolia, A, Vijayan, M. | 登録日 | 2008-09-05 | 公開日 | 2009-07-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action Acta Crystallogr.,Sect.D, 65, 2009
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3AF1
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![BU of 3af1 by Molmil](/molmil-images/mine/3af1) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with GDP | 分子名称: | CHLORIDE ION, CITRATE ANION, GLYCEROL, ... | 著者 | Chetnani, B, Kumar, P, Surolia, A, Vijayan, M. | 登録日 | 2010-02-19 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | M. tuberculosis pantothenate kinase: dual substrate specificity and unusual changes in ligand locations J.Mol.Biol., 400, 2010
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3AVO
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![BU of 3avo by Molmil](/molmil-images/mine/3avo) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with Pantothenate | 分子名称: | CITRATE ANION, GLYCEROL, PANTOTHENOIC ACID, ... | 著者 | Chetnani, B, Kumar, P, Abhinav, K.V, Chhibber, M, Surolia, A, Vijayan, M. | 登録日 | 2011-03-06 | 公開日 | 2011-08-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Location and conformation of pantothenate and its derivatives in Mycobacterium tuberculosis pantothenate kinase: insights into enzyme action Acta Crystallogr.,Sect.D, 67, 2011
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3AF4
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![BU of 3af4 by Molmil](/molmil-images/mine/3af4) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with GMPPCP | 分子名称: | GLYCEROL, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Pantothenate kinase | 著者 | Chetnani, B, Kumar, P, Surolia, A, Vijayan, M. | 登録日 | 2010-02-22 | 公開日 | 2010-05-26 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | M. tuberculosis pantothenate kinase: dual substrate specificity and unusual changes in ligand locations J.Mol.Biol., 400, 2010
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3AVP
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![BU of 3avp by Molmil](/molmil-images/mine/3avp) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with Pantothenol | 分子名称: | (2S)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide, CITRATE ANION, GLYCEROL, ... | 著者 | Chetnani, B, Kumar, P, Abhinav, K.V, Chhibber, M, Surolia, A, Vijayan, M. | 登録日 | 2011-03-06 | 公開日 | 2011-08-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Location and conformation of pantothenate and its derivatives in Mycobacterium tuberculosis pantothenate kinase: insights into enzyme action Acta Crystallogr.,Sect.D, 67, 2011
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2ZS7
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![BU of 2zs7 by Molmil](/molmil-images/mine/2zs7) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with citrate anion | 分子名称: | CITRATE ANION, GLYCEROL, Pantothenate kinase, ... | 著者 | Chetnani, B, Das, S, Kumar, P, Surolia, A, Vijayan, M. | 登録日 | 2008-09-03 | 公開日 | 2009-07-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action Acta Crystallogr.,Sect.D, 65, 2009
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4BFX
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![BU of 4bfx by Molmil](/molmil-images/mine/4bfx) | Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1f) and phosphate | 分子名称: | 2,6-difluoro-N-[1-(5-{[2-(4-fluorophenoxy)ethyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)ethyl]benzamide, PANTOTHENATE KINASE, PHOSPHATE ION | 著者 | Bjorkelid, C, Bergfors, T, Jones, T.A. | 登録日 | 2013-03-22 | 公開日 | 2013-05-15 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
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2ZS9
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![BU of 2zs9 by Molmil](/molmil-images/mine/2zs9) | Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with ADP and Pantothenate | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, PANTOTHENOIC ACID, ... | 著者 | Chetnani, B, Das, S, Kumar, P, Surolia, A, Vijayan, M. | 登録日 | 2008-09-04 | 公開日 | 2009-07-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action Acta Crystallogr.,Sect.D, 65, 2009
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