4BFY

Crystal structure of Mycobacterium tuberculosis PanK in complex with a biaryl inhibitory compound (2a) and phosphate

Summary for 4BFY

Entry DOI	10.2210/pdb4bfy/pdb
Related	4BFS 4BFT 4BFU 4BFV 4BFW 4BFX 4BFZ
Descriptor	PANTOTHENATE KINASE, PHOSPHATE ION, 2-[4-(4-cyanophenyl)-3-[(4-pyridin-2-ylpiperazin-1-yl)methyl]phenoxy]acetic acid, ... (4 entities in total)
Functional Keywords	transferase, coa pathway, pank, inhibitor
Biological source	MYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains	2
Total formula weight	74114.36
Authors	Bjorkelid, C.,Bergfors, T.,Jones, T.A. (deposition date: 2013-03-22, release date: 2013-05-15, Last modification date: 2023-12-20)
Primary citation	Bjorkelid, C.,Bergfors, T.,Raichurkar, A.K.V.,Mukherjee, K.,Krishnan, M.,Bandodkar, B.,Jones, T.A. Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288:18260-, 2013 Cited by PubMed: 23661699 DOI: 10.1074/JBC.M113.476473 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation