4BFT
Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1b) and phosphate
Summary for 4BFT
Entry DOI | 10.2210/pdb4bft/pdb |
Related | 4BFS 4BFU 4BFV 4BFW 4BFX 4BFY 4BFZ |
Descriptor | PANTOTHENATE KINASE, PHOSPHATE ION, 2-chloro-N-[1-(5-{[2-(4-fluorophenoxy)ethyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)ethyl]benzamide, ... (4 entities in total) |
Functional Keywords | transferase, coa pathway, inhibitor |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 2 |
Total formula weight | 74127.23 |
Authors | Bjorkelid, C.,Bergfors, T.,Jones, T.A. (deposition date: 2013-03-22, release date: 2013-05-15, Last modification date: 2023-12-20) |
Primary citation | Bjorkelid, C.,Bergfors, T.,Raichurkar, A.K.V.,Mukherjee, K.,Krishnan, M.,Bandodkar, B.,Jones, T.A. Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288:18260-, 2013 Cited by PubMed: 23661699DOI: 10.1074/JBC.M113.476473 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
Download full validation report