4BFV

Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1d) and phosphate

Summary for 4BFV

Entry DOI	10.2210/pdb4bfv/pdb
Related	4BFS 4BFT 4BFU 4BFW 4BFX 4BFY 4BFZ
Descriptor	PANTOTHENATE KINASE, PHOSPHATE ION, N-[1-(4-methyl-5-{[2-(2-methylphenoxy)ethyl]sulfanyl}-4H-1,2,4-triazol-3-yl)ethyl]-2-(trifluoromethyl)benzamide, ... (4 entities in total)
Functional Keywords	transferase, coa pathway, inhibitor
Biological source	MYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains	2
Total formula weight	74186.40
Authors	Bjorkelid, C.,Bergfors, T.,Jones, T.A. (deposition date: 2013-03-22, release date: 2013-05-15, Last modification date: 2023-12-20)
Primary citation	Bjorkelid, C.,Bergfors, T.,Raichurkar, A.K.V.,Mukherjee, K.,Krishnan, M.,Bandodkar, B.,Jones, T.A. Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288:18260-, 2013 Cited by PubMed: 23661699 DOI: 10.1074/JBC.M113.476473 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation