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PDB: 1174 件
4E0K
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BU of 4e0k by Molmil
Crystal Structure of the amyloid-fibril forming peptide KDWSFY derived from human Beta 2 Microglobulin (58-63)
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Amyloidogenic peptide segment KDWSFY, SODIUM ION
著者Zhao, M, Liu, C, Sawaya, M.R, Eisenberg, D.
登録日2012-03-04
公開日2012-12-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (0.97 Å)
主引用文献Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates.
Proc.Natl.Acad.Sci.USA, 109, 2012
1K5N
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BU of 1k5n by Molmil
HLA-B*2709 BOUND TO NONA-PEPTIDE M9
分子名称: GLYCEROL, beta-2-microglobulin, light chain, ...
著者Hulsmeyer, M, Hillig, R.C, Volz, A, Ruhl, M, Schroder, W, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
登録日2001-10-11
公開日2002-10-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献HLA-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural Alterations
J.Biol.Chem., 277, 2002
3MRE
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BU of 3mre by Molmil
Crystal Structure of MHC class I HLA-A2 molecule complexed with EBV bmlf1-280-288 nonapeptide
分子名称: 9-meric peptide from mRNA export factor EB2, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Gras, S, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D.
登録日2010-04-29
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans.
J.Immunol., 193, 2014
2YXF
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BU of 2yxf by Molmil
The high resolution crystal structure of beta2-microglobulin under physiological conditions
分子名称: Beta-2-microglobulin
著者Iwata, K, Matsuura, T, Nakagawa, A, Goto, Y.
登録日2007-04-26
公開日2007-10-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献High-resolution Crystal Structure of {beta}2-Microglobulin Formed at pH 7.0
J.Biochem.(Tokyo), 142, 2007
8E2Z
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BU of 8e2z by Molmil
Structures of HLA-B8E76C loaded with long peptides reveal novel features at the N-terminus of the groove
分子名称: ALA-PHE-ALA-LYS-LYS-LYS-TYR-CYS-LEU, Beta-2-microglobulin, MHC class I protein (Fragment)
著者Li, L, Bouvier, M.
登録日2022-08-16
公開日2023-08-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.13 Å)
主引用文献Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing.
Nat Commun, 14, 2023
7NMR
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BU of 7nmr by Molmil
Crystal structure of beta-2-microglobulin D76S mutant
分子名称: Beta-2-microglobulin, GLYCEROL
著者Guthertz, N.
登録日2021-02-23
公開日2022-08-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
8ROP
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BU of 8rop by Molmil
Crystal structure of HLA B*18:01 in complex with QEIRTFSF, an 8-mer epitope from Influenza A
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, CHLORIDE ION, ...
著者Murdolo, L.D, Maddumage, J.C, Gras, S.
登録日2024-01-12
公開日2024-05-08
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Crystal structure of HLA B*18:01 in complex with QEIRTFSF, an 8-mer epitope from Influenza A
To Be Published
7R7W
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BU of 7r7w by Molmil
Crystal structure of HLA-B*5301 complex with an HIV-1 Gag-derived epitope QW9 S3T variant
分子名称: Beta-2-microglobulin, GLN-ALA-THR-GLN-GLU-VAL-LYS-ASN-TRP, MHC class I antigen
著者Li, X.L, Tan, K.M, Walker, B.D, Wang, J.H.
登録日2021-06-25
公開日2022-06-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide.
Nat Commun, 14, 2023
4U1M
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BU of 4u1m by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-15
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.18 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
3CZF
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BU of 3czf by Molmil
Crystal structure of HLA-B*2709 complexed with the glucagon receptor (GR) peptide (residues 412-420)
分子名称: BETA-2-MICROGLOBULIN, GLUCAGON RECEPTOR PEPTIDE, GLYCEROL, ...
著者Loll, B, Fiorillo, M.T, Rueckert, C, Saenger, W, Sorrentino, R, Ziegler, A, Uchanska-Ziegler, B.
登録日2008-04-29
公開日2009-04-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Conformational Plasticity of HLA-B27 Molecules Correlates Inversely With Efficiency of Negative T Cell Selection.
Front Immunol, 11, 2020
7NMO
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BU of 7nmo by Molmil
Crystal structure of beta-2-microglobulin D76A mutant
分子名称: Beta-2-microglobulin
著者Guthertz, N.
登録日2021-02-23
公開日2022-08-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NMT
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BU of 7nmt by Molmil
Crystal structure of beta-2-microglobulin D76G mutant
分子名称: Beta-2-microglobulin
著者Guthertz, N.
登録日2021-02-23
公開日2022-08-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7NMC
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BU of 7nmc by Molmil
Crystal structure of beta-2-microglobulin D76E mutant
分子名称: Beta-2-microglobulin, GLYCEROL, TRIETHYLENE GLYCOL
著者Guthertz, N.
登録日2021-02-23
公開日2022-08-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
6Y26
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BU of 6y26 by Molmil
Crystal structure of HLA-B2705 complexed with the nona-peptide mA
分子名称: Beta-2-microglobulin, CHLORIDE ION, GLY-ARG-LEU-ASN-ALA-PRO-ILE-LYS-VAL, ...
著者Loll, B, Rueckert, C, Ziegler, B.-U, Ziegler, A.
登録日2020-02-15
公開日2020-12-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献A CENTRAL PEPTIDE RESIDUE CAN CONTROL MHC POLYMORPHISM-DEPENDENT ANTIGEN PRESENTATION
to be published
6MT3
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BU of 6mt3 by Molmil
Crystal Structure of HLA-B*18:01 in complex with NP338 influenza peptide
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-18 alpha chain, ...
著者Gras, S.
登録日2018-10-19
公開日2019-02-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Broad CD8+T cell cross-recognition of distinct influenza A strains in humans.
Nat Commun, 9, 2018
8EC5
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BU of 8ec5 by Molmil
Structures of HLA-B8E76C loaded with long peptides reveal novel features at the N-terminus of the groove
分子名称: Beta-2-microglobulin, MHC class I antigen, peptide RARARARARARAFVKKKYCL
著者Li, L, Bouvier, M.
登録日2022-09-01
公開日2023-07-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献Crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing.
Nat Commun, 14, 2023
4RMT
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BU of 4rmt by Molmil
Crystal structure of the D98N Beta-2 Microglobulin mutant
分子名称: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
著者de Rosa, M, Bolognesi, M, Ricagno, S.
登録日2014-10-22
公開日2015-11-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.242 Å)
主引用文献Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis.
Plos One, 10, 2015
7NN5
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BU of 7nn5 by Molmil
Crystal structure of beta-2-microglobulin D76K mutant
分子名称: Beta-2-microglobulin
著者Guthertz, N.
登録日2021-02-24
公開日2022-08-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.242 Å)
主引用文献The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TUC
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BU of 7tuc by Molmil
Crystal structure of HLA-B*44:05 (T73C) with 9mer EEFGRAFSF
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Jiang, J, Natarajan, K, Kim, E, Boyd, L.F, Margulies, D.H.
登録日2022-02-02
公開日2022-09-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation.
Nat Commun, 13, 2022
7NMY
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BU of 7nmy by Molmil
Crystal structure of beta-2-microglobulin D76Y mutant
分子名称: Beta-2-microglobulin
著者Guthertz, N.
登録日2021-02-23
公開日2022-08-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis.
Proc.Natl.Acad.Sci.USA, 119, 2022
6Y2A
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BU of 6y2a by Molmil
Crystal structure of HLA-B2705 complexed with the nona-peptide mQ
分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ...
著者Loll, B, Rueckert, C, Ziegler, B.-U, Ziegler, A.
登録日2020-02-15
公開日2020-12-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献A CENTRAL PEPTIDE RESIDUE CAN CONTROL MHC POLYMORPHISM-DEPENDENT ANTIGEN PRESENTATION
to be published
3IB4
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BU of 3ib4 by Molmil
The double mutant of Beta-2 microglobulin K58P-W60G
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Beta-2-microglobulin
著者Colombo, M, Ricagno, S, Bolognesi, M.
登録日2009-07-15
公開日2010-07-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal structure of the Beta-2 microglobulin mutant K58P-W60G
To be Published
6V2O
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BU of 6v2o by Molmil
HLA-B*57:01 presenting the peptide ASLNLPAVSW
分子名称: ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ...
著者Maclachlan, B, Rossjohn, J, Vivian, J.P.
登録日2019-11-25
公開日2020-05-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function.
Proc.Natl.Acad.Sci.USA, 117, 2020
7WJ2
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BU of 7wj2 by Molmil
Crystal structure of HLA-C*1402 complexed with 8-mer HIV gag peptide
分子名称: 1,2-ETHANEDIOL, 8-mer peptide, ACETATE ION, ...
著者Kuroha, J, Morita, D, Asa, M, Sugita, M.
登録日2022-01-05
公開日2022-06-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding.
J.Biol.Chem., 298, 2022
6Y29
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BU of 6y29 by Molmil
Crystal structure of HLA-B2709 complexed with the nona-peptide mE
分子名称: Beta-2-microglobulin, GLYCEROL, Lymphocyte antigen HLA-B27, ...
著者Loll, B, Rueckert, C, Ziegler, B.-U, Ziegler, A.
登録日2020-02-15
公開日2020-12-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献A CENTRAL PEPTIDE RESIDUE CAN CONTROL MHC POLYMORPHISM-DEPENDENT ANTIGEN PRESENTATION
to be published

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