4E0K
| Crystal Structure of the amyloid-fibril forming peptide KDWSFY derived from human Beta 2 Microglobulin (58-63) | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Amyloidogenic peptide segment KDWSFY, SODIUM ION | 著者 | Zhao, M, Liu, C, Sawaya, M.R, Eisenberg, D. | 登録日 | 2012-03-04 | 公開日 | 2012-12-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | 主引用文献 | Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates. Proc.Natl.Acad.Sci.USA, 109, 2012
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1K5N
| HLA-B*2709 BOUND TO NONA-PEPTIDE M9 | 分子名称: | GLYCEROL, beta-2-microglobulin, light chain, ... | 著者 | Hulsmeyer, M, Hillig, R.C, Volz, A, Ruhl, M, Schroder, W, Saenger, W, Ziegler, A, Uchanska-Ziegler, B. | 登録日 | 2001-10-11 | 公開日 | 2002-10-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | HLA-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural Alterations J.Biol.Chem., 277, 2002
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3MRE
| Crystal Structure of MHC class I HLA-A2 molecule complexed with EBV bmlf1-280-288 nonapeptide | 分子名称: | 9-meric peptide from mRNA export factor EB2, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans. J.Immunol., 193, 2014
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8E2Z
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2YXF
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7NMR
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8ROP
| Crystal structure of HLA B*18:01 in complex with QEIRTFSF, an 8-mer epitope from Influenza A | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CHLORIDE ION, ... | 著者 | Murdolo, L.D, Maddumage, J.C, Gras, S. | 登録日 | 2024-01-12 | 公開日 | 2024-05-08 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Characterisation of novel influenza-derived HLA-B*18:01-restricted epitopes. Clin Transl Immunology, 13, 2024
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7R7W
| Crystal structure of HLA-B*5301 complex with an HIV-1 Gag-derived epitope QW9 S3T variant | 分子名称: | Beta-2-microglobulin, GLN-ALA-THR-GLN-GLU-VAL-LYS-ASN-TRP, MHC class I antigen | 著者 | Li, X.L, Tan, K.M, Walker, B.D, Wang, J.H. | 登録日 | 2021-06-25 | 公開日 | 2022-06-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | 主引用文献 | Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide. Nat Commun, 14, 2023
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4U1M
| HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | 登録日 | 2014-07-15 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape. Retrovirology, 12, 2015
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6Y26
| Crystal structure of HLA-B2705 complexed with the nona-peptide mA | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, GLY-ARG-LEU-ASN-ALA-PRO-ILE-LYS-VAL, ... | 著者 | Loll, B, Rueckert, C, Ziegler, B.-U, Ziegler, A. | 登録日 | 2020-02-15 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | A CENTRAL PEPTIDE RESIDUE CAN CONTROL
MHC POLYMORPHISM-DEPENDENT ANTIGEN PRESENTATION to be published
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7NMO
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7NMT
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7NMC
| Crystal structure of beta-2-microglobulin D76E mutant | 分子名称: | Beta-2-microglobulin, GLYCEROL, TRIETHYLENE GLYCOL | 著者 | Guthertz, N. | 登録日 | 2021-02-23 | 公開日 | 2022-08-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | The effect of mutation on an aggregation-prone protein: An in vivo, in vitro, and in silico analysis. Proc.Natl.Acad.Sci.USA, 119, 2022
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3CZF
| Crystal structure of HLA-B*2709 complexed with the glucagon receptor (GR) peptide (residues 412-420) | 分子名称: | BETA-2-MICROGLOBULIN, GLUCAGON RECEPTOR PEPTIDE, GLYCEROL, ... | 著者 | Loll, B, Fiorillo, M.T, Rueckert, C, Saenger, W, Sorrentino, R, Ziegler, A, Uchanska-Ziegler, B. | 登録日 | 2008-04-29 | 公開日 | 2009-04-07 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Conformational Plasticity of HLA-B27 Molecules Correlates Inversely With Efficiency of Negative T Cell Selection. Front Immunol, 11, 2020
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6MT3
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8EC5
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4RMT
| Crystal structure of the D98N Beta-2 Microglobulin mutant | 分子名称: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | de Rosa, M, Bolognesi, M, Ricagno, S. | 登録日 | 2014-10-22 | 公開日 | 2015-11-18 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.242 Å) | 主引用文献 | Decoding the Structural Bases of D76N 2-Microglobulin High Amyloidogenicity through Crystallography and Asn-Scan Mutagenesis. Plos One, 10, 2015
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7NN5
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3IB4
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7TUC
| Crystal structure of HLA-B*44:05 (T73C) with 9mer EEFGRAFSF | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Jiang, J, Natarajan, K, Kim, E, Boyd, L.F, Margulies, D.H. | 登録日 | 2022-02-02 | 公開日 | 2022-09-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation. Nat Commun, 13, 2022
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7NMY
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6Y2A
| Crystal structure of HLA-B2705 complexed with the nona-peptide mQ | 分子名称: | Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... | 著者 | Loll, B, Rueckert, C, Ziegler, B.-U, Ziegler, A. | 登録日 | 2020-02-15 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | A CENTRAL PEPTIDE RESIDUE CAN CONTROL
MHC POLYMORPHISM-DEPENDENT ANTIGEN PRESENTATION to be published
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6V2O
| HLA-B*57:01 presenting the peptide ASLNLPAVSW | 分子名称: | ACETATE ION, Beta-2-microglobulin, MHC class I antigen, ... | 著者 | Maclachlan, B, Rossjohn, J, Vivian, J.P. | 登録日 | 2019-11-25 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | 主引用文献 | The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function. Proc.Natl.Acad.Sci.USA, 117, 2020
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6Y29
| Crystal structure of HLA-B2709 complexed with the nona-peptide mE | 分子名称: | Beta-2-microglobulin, GLYCEROL, Lymphocyte antigen HLA-B27, ... | 著者 | Loll, B, Rueckert, C, Ziegler, B.-U, Ziegler, A. | 登録日 | 2020-02-15 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | A CENTRAL PEPTIDE RESIDUE CAN CONTROL
MHC POLYMORPHISM-DEPENDENT ANTIGEN PRESENTATION to be published
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7WJ2
| Crystal structure of HLA-C*1402 complexed with 8-mer HIV gag peptide | 分子名称: | 1,2-ETHANEDIOL, 8-mer peptide, ACETATE ION, ... | 著者 | Kuroha, J, Morita, D, Asa, M, Sugita, M. | 登録日 | 2022-01-05 | 公開日 | 2022-06-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding. J.Biol.Chem., 298, 2022
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