5WMN
 
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6D2R
 | | HLA-B*57:01 presenting GSFDYSGVHLW | | 分子名称: | Beta-2-microglobulin, GLY-SER-PHE-ASP-TYR-SER-GLY-VAL-HIS-LEU-TRP, HLA class I histocompatibility antigen, ... | | 著者 | Vivian, J.P, Rossjohn, J. | | 登録日 | 2018-04-13 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands.
Sci Immunol, 3, 2018
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5DEG
 | | Crystal structure of B*27:06 bound to the pVIPR peptide | | 分子名称: | Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... | | 著者 | Loll, B, Fabian, H, Hee, C.S, Huser, H, Uchanska-Ziegler, B, Ziegler, A. | | 登録日 | 2015-08-25 | | 公開日 | 2015-11-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Increased Conformational Flexibility of HLA-B*27 Subtypes Associated With Ankylosing Spondylitis.
Arthritis Rheumatol, 68, 2016
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8GLH
 | | Crystal Structure of Human CD1b in Complex with Endogenous PC C40:5 | | 分子名称: | (11E)-hexadec-11-enoic acid, 1,2-ETHANEDIOL, Beta-2-microglobulin, ... | | 著者 | Farquhar, R, Rossjohn, J, Shahine, A. | | 登録日 | 2023-03-22 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.
Cell, 186, 2023
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8EMG
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7ZT7
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4NT6
 | | HLA-C*0801 Crystal Structure | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, Cw-8 alpha chain, ... | | 著者 | Liu, J.X, Toh, X.Y, Ren, E.C. | | 登録日 | 2013-12-01 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | The immunodominant influenza A virus M158-66 cytotoxic T lymphocyte epitope exhibits degenerate class I major histocompatibility complex restriction in humans.
J.Virol., 88, 2014
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6PUL
 | | Structure of human MAIT A-F7 TCR in complex with human MR1 3'D-5-OP-RU | | 分子名称: | 1,3-dideoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-erythro-pentitol, ACETATE ION, Beta-2-microglobulin, ... | | 著者 | Awad, W, Keller, A.N, Rossjohn, J. | | 登録日 | 2019-07-18 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | The molecular basis underpinning the potency and specificity of MAIT cell antigens.
Nat.Immunol., 21, 2020
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8XG2
 | | The structure of HLA-A/Pep14 | | 分子名称: | Beta-2-microglobulin, HLA class I heavy chain, Spike protein S1 | | 著者 | Zhang, J.N, Yue, C, Liu, J. | | 登録日 | 2023-12-14 | | 公開日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
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3KPQ
 | | Crystal Structure of HLA B*4405 in complex with EEYLKAWTF, a mimotope | | 分子名称: | Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ... | | 著者 | Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. | | 登録日 | 2009-11-16 | | 公開日 | 2009-12-22 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | T cell allorecognition via molecular mimicry.
Immunity, 31, 2009
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7SA2
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8ELH
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6PUC
 | | Structure of human MAIT A-F7 TCR in complex with human MR1-5-OP-RU | | 分子名称: | 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, CHLORIDE ION, ... | | 著者 | Awad, W, Rossjohn, J. | | 登録日 | 2019-07-18 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The molecular basis underpinning the potency and specificity of MAIT cell antigens.
Nat.Immunol., 21, 2020
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2HJK
 | | Crystal Structure of HLA-B5703 and HIV-1 peptide | | 分子名称: | Beta-2-microglobulin, Gag protein, HLA class I histocompatibility antigen B-57 | | 著者 | Gillespie, G.M.A, Stewart-Jones, G, Rengasamy, J, Beattie, T, Bwayo, J.J, Plummer, F.A. | | 登録日 | 2006-06-30 | | 公開日 | 2006-10-03 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection.
J.Immunol., 177, 2006
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4Z77
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3VFR
 | | crystal structure of HLA B*3508LPEP-P4Ala, peptide mutant P4-ala | | 分子名称: | Beta-2-microglobulin, LPEP peptide from EBV, P4A, ... | | 著者 | Liu, Y.C, Rossjohn, J, Gras, S. | | 登録日 | 2012-01-10 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
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6C98
 | | Crystal structure of FcRn bound to UCB-84 | | 分子名称: | 1-[7-(3-fluorophenyl)-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethan-1-one, Beta-2-microglobulin, CYSTEINE, ... | | 著者 | Fox III, D, Lukacs, C.M. | | 登録日 | 2018-01-25 | | 公開日 | 2018-05-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
PLoS Biol., 16, 2018
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8GLE
 | | Crystal Structure of Human CD1b in Complex with Lysosulfatide | | 分子名称: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl 3-O-sulfo-beta-D-galactopyranoside, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Shahine, A. | | 登録日 | 2023-03-22 | | 公開日 | 2023-09-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.
Cell, 186, 2023
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3VFS
 | | crystal structure of HLA B*3508LPEP-P5Ala , peptide mutant P5-ala | | 分子名称: | Beta-2-microglobulin, LPEP peptide from EBV, P5A, ... | | 著者 | Liu, Y.C, Rossjohn, J, Gras, S. | | 登録日 | 2012-01-10 | | 公開日 | 2012-02-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
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5ENW
 | | Structure of HLA-A2:01 with peptide G9L | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Remesh, S.G, Zajonc, D.M. | | 登録日 | 2015-11-09 | | 公開日 | 2016-11-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.
J. Biol. Chem., 292, 2017
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5EO1
 | | Crystal Structure of HLA-B0702-RL9 | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ... | | 著者 | Josephs, T.M, Gras, S, Rossjohn, J. | | 登録日 | 2015-11-10 | | 公開日 | 2016-02-24 | | 最終更新日 | 2016-04-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | HIV-1-Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection.
J Immunol., 196, 2016
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1JF1
 | | Crystal structure of HLA-A2*0201 in complex with a decameric altered peptide ligand from the MART-1/Melan-A | | 分子名称: | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, ZINC ION, ... | | 著者 | Sliz, P, Michielin, O, Cerottini, J.C, Luescher, I, Romero, P, Karplus, M, Wiley, D.C. | | 登録日 | 2001-06-19 | | 公開日 | 2001-09-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes.
J.Immunol., 167, 2001
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3VFP
 | | crystal structure of HLA B*3508 LPEP158G, HLA mutant Gly158 | | 分子名称: | ACETATE ION, Beta-2-microglobulin, LPEP peptide from EBV, ... | | 著者 | Liu, Y.C, Rossjohn, J, Gras, S. | | 登録日 | 2012-01-10 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
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7N4K
 | | 6218 TCR in complex with H2-Db PA 224 | | 分子名称: | Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain, ... | | 著者 | Szeto, C, Gras, S. | | 登録日 | 2021-06-04 | | 公開日 | 2022-07-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.
Nat Commun, 13, 2022
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4PRA
 | | Crystal structure of a HLA-B*35:01-HPVG-Q5 | | 分子名称: | Beta-2-microglobulin, Epstein-Barr nuclear antigen 1, MHC class I antigen | | 著者 | Yu Chih, L, Rossjohn, J, Gras, S. | | 登録日 | 2014-03-05 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism.
J.Biol.Chem., 289, 2014
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