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PDB: 462 件

6WD3
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Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure II-B1)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
5KCR
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Cryo-EM structure of the Escherichia coli 70S ribosome in complex with antibiotic Avilamycin C, mRNA and P-site tRNA at 3.6A resolution
分子名称: (2R,3S,4R,6S)-4-hydroxy-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7aR)-4'-hydroxy-6-{[(2S,3R,4R,5S,6R)-3-hydroxy-2-{[(2R,3S,4S,5S,6S)-4-hydroxy-6-({(2R,3aS,3a'R,6S,6'R,7R,7'R,7aR,7a'R)-7'-hydroxy-7'-[(1S)-1-hydroxyethyl]-6'-methyl-7-[(2-methylpropanoyl)oxy]octahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}oxy)-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl]oxy}-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Arenz, S, Juette, M.F, Graf, M, Nguyen, F, Huter, P, Polikanov, Y.S, Blanchard, S.C, Wilson, D.N.
登録日2016-06-06
公開日2016-08-17
最終更新日2019-12-25
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.
Proc.Natl.Acad.Sci.USA, 113, 2016
3J9Z
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Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J.
登録日2015-03-27
公開日2015-07-01
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
5NP6
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70S structure prior to bypassing
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Agirrezabala, X, Samatova, E, Klimova, M, Zamora, M, Gil-Carton, D, Rodnina, M, Valle, M.
登録日2017-04-13
公開日2017-06-14
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Ribosome rearrangements at the onset of translational bypassing.
Sci Adv, 3, 2017
6WD2
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Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure II-A)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
6WDK
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Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Non-cognate Structure V-A2)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
6WD5
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Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure II-C1)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
6WDM
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Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Non-cognate Structure V-B2)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
3JA1
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Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J.
登録日2015-03-30
公開日2015-07-01
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
5WF0
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70S ribosome-EF-Tu H84A complex with GTP and near-cognate tRNA (Complex C2)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Fislage, M, Frank, J.
登録日2017-07-11
公開日2018-05-02
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A.
Nucleic Acids Res., 46, 2018
6OSK
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RF1 accommodated 70S complex at 60 ms
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J.
登録日2019-05-01
公開日2019-06-26
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
5JU8
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Cryo-EM structure of an ErmBL-stalled ribosome in complex with P-, and E-tRNA
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Arenz, S, Bock, L.V, Graf, M, Innis, C.A, Beckmann, R, Grubmueller, H, Vaiana, A.C, Wilson, D.N.
登録日2016-05-10
公開日2016-07-20
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest.
Nat Commun, 7, 2016
5LZA
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BU of 5lza by Molmil
Structure of the 70S ribosome with SECIS-mRNA and P-site tRNA (Initial complex, IC)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Fischer, N, Neumann, P, Bock, L.V, Maracci, C, Wang, Z, Paleskava, A, Konevega, A.L, Schroeder, G.F, Grubmueller, H, Ficner, R, Rodnina, M.V, Stark, H.
登録日2016-09-29
公開日2016-11-23
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The pathway to GTPase activation of elongation factor SelB on the ribosome.
Nature, 540, 2016
5UYL
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BU of 5uyl by Molmil
70S ribosome bound with cognate ternary complex base-paired to A site codon (Structure II)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
登録日2017-02-24
公開日2017-06-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Ensemble cryo-EM elucidates the mechanism of translation fidelity.
Nature, 546, 2017
3JBU
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Mechanisms of Ribosome Stalling by SecM at Multiple Elongation Steps
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhang, J, Pan, X.J, Yan, K.G, Sun, S, Gao, N, Sui, S.F.
登録日2015-10-16
公開日2016-01-27
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Mechanisms of ribosome stalling by SecM at multiple elongation steps
Elife, 4, 2015
8PHJ
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BU of 8phj by Molmil
cA4-bound Cami1 in complex with 70S ribosome
分子名称: 16S rRNA, 23S rRNA (2862-MER), 5S rRNA, ...
著者Tamulaitiene, G, Mogila, I, Sasnauskas, G, Tamulaitis, G.
登録日2023-06-20
公開日2023-12-13
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling.
Science, 382, 2023
4V89
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Crystal Structure of Release Factor RF3 Trapped in the GTP State on a Rotated Conformation of the Ribosome (without viomycin)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhou, J, Lancaster, L, Trakhanov, S, Noller, H.F.
登録日2011-11-17
公開日2014-07-09
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Crystal structure of release factor RF3 trapped in the GTP state on a rotated conformation of the ribosome.
Rna, 18, 2012
6YSU
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Structure of the P+0 ArfB-ribosome complex in the post-hydrolysis state
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
登録日2020-04-23
公開日2020-08-19
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
6WDJ
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Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Non-cognate Structure V-A1)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Korostelev, A.A.
登録日2020-03-31
公開日2020-07-01
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
5L3P
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BU of 5l3p by Molmil
Cryo-EM structure of stringent response factor RelA bound to ErmCL-stalled ribosome complex
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Arenz, S, Wilson, D.N.
登録日2016-05-24
公開日2016-07-20
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis.
Nucleic Acids Res., 44, 2016
3JCD
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Structure of Escherichia coli EF4 in posttranslocational ribosomes (Post EF4)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Zhang, D, Yan, K, Liu, G, Song, G, Luo, J, Shi, Y, Cheng, E, Wu, S, Jiang, T, Low, J, Gao, N, Qin, Y.
登録日2015-12-01
公開日2016-01-13
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome
Nat. Struct. Mol. Biol., 23, 2016
7BL2
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pre-50S-ObgE particle state 1
分子名称: 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ...
著者Hilal, T, Nikolay, R, Schmidt, S, Spahn, C.M.T.
登録日2021-01-18
公開日2021-05-12
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Snapshots of native pre-50S ribosomes reveal a biogenesis factor network and evolutionary specialization.
Mol.Cell, 81, 2021
3JCJ
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Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T.
登録日2015-12-18
公開日2016-03-09
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
6XDQ
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Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 30 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
著者Molodtsov, V, Ebright, R.H, Wang, C, Su, M.
登録日2020-06-11
公開日2020-09-02
最終更新日2020-09-23
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of transcription-translation coupling.
Science, 369, 2020
6Q9A
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Structure of tmRNA SmpB bound past E site of E. coli 70S ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rae, C.D.
登録日2018-12-17
公開日2019-04-17
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献How a circularized tmRNA moves through the ribosome.
Science, 363, 2019

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