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PDB: 812 件
167L
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PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
分子名称: T4 LYSOZYME
著者Weaver, L.H, Zhang, X.-J, Matthews, B.W.
登録日1995-03-24
公開日1995-07-10
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
5VNQ
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BU of 5vnq by Molmil
Neutron crystallographic structure of perdeuterated T4 lysozyme cysteine-free pseudo-wild type at cryogenic temperature
分子名称: CHLORIDE ION, Endolysin
著者Li, L, Shukla, S, Meilleur, F, Standaert, R.F, Pierce, J, Myles, D.A.A, Cuneo, M.J.
登録日2017-05-01
公開日2017-07-26
最終更新日2023-10-04
実験手法NEUTRON DIFFRACTION (2.2 Å)
主引用文献Neutron crystallographic studies of T4 lysozyme at cryogenic temperature.
Protein Sci., 26, 2017
5X93
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Human endothelin receptor type-B in complex with antagonist K-8794
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-pyrimidin-4-yl]oxy-N-(2,6-dimethylphenyl)propanamide, CHOLESTEROL, ...
著者Shihoya, W, Nishizawa, T, Yamashita, K, Hirata, K, Okuta, A, Tani, K, Fujiyoshi, Y, Doi, T, Nureki, O.
登録日2017-03-05
公開日2017-08-16
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog
Nat. Struct. Mol. Biol., 24, 2017
1CU0
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BU of 1cu0 by Molmil
T4 LYSOZYME MUTANT I78M
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME
著者Gassner, N.C, Baase, W.A, Lindstrom, J.D, Lu, J, Matthews, B.W.
登録日1999-08-20
公開日1999-11-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding.
Biochemistry, 38, 1999
3GUM
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BU of 3gum by Molmil
T4 lysozyme M102E/L99A mutant with buried charge in apolar cavity--p-xylene binding
分子名称: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
著者Liu, L, Matthews, B.W.
登録日2009-03-30
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Use of stabilizing mutations to engineer a charged group within a ligand-binding hydrophobic cavity in T4 lysozyme.
Biochemistry, 48, 2009
5VBA
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BU of 5vba by Molmil
Structure of EspG1 chaperone from the type VII (ESX-1) secretion system determined with the assistance of N-terminal T4 lysozyme fusion
分子名称: CHLORIDE ION, Lysozyme, ESX-1 secretion-associated protein EspG1 chimera
著者Korotkov, K.V.
登録日2017-03-29
公開日2017-07-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
4IAP
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BU of 4iap by Molmil
Crystal structure of PH domain of Osh3 from Saccharomyces cerevisiae
分子名称: Oxysterol-binding protein homolog 3,Endolysin,Oxysterol-binding protein homolog 3, SULFATE ION
著者Tong, J, Im, Y.J.
登録日2012-12-07
公開日2013-07-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins
Structure, 21, 2013
196L
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THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W.
登録日1995-11-06
公開日1996-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme.
J.Mol.Biol., 259, 1996
1C62
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T4 LYSOZYME MUTANT C54T/C97A/F153A IN THE PRESENCE OF 8 ATM XENON
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, PROTEIN (LYSOZYME), ...
著者Quillin, M.L, Matthews, B.W.
登録日1999-12-21
公開日2000-10-04
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Size versus polarizability in protein-ligand interactions: binding of noble gases within engineered cavities in phage T4 lysozyme.
J.Mol.Biol., 302, 2000
3G3W
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BU of 3g3w by Molmil
Crystal structure of spin labeled T4 Lysozyme (T151R1) at 291 K
分子名称: 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ...
著者Fleissner, M.R, Cascio, D, Hubbell, W.L.
登録日2009-02-02
公開日2009-05-05
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural origin of weakly ordered nitroxide motion in spin-labeled proteins.
Protein Sci., 18, 2009
4YXC
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BU of 4yxc by Molmil
Complex of FliM(SPOA)::FliN fusion protein and FliH(APAR)::T4lysozyme fusion protein
分子名称: Flagellar assembly protein H,Endolysin, Flagellar motor switch protein FliM,Flagellar motor switch protein FliN
著者Notti, R.Q, Stebbins, C.E.
登録日2015-03-23
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
1QTV
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BU of 1qtv by Molmil
T26E APO STRUCTURE OF T4 LYSOZYME
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, PROTEIN (T4 LYSOZYME)
著者Kuroki, R, Weaver, L.H, Matthews, B.W.
登録日1999-06-29
公開日1999-07-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of the conversion of T4 lysozyme into a transglycosidase by reengineering the active site.
Proc.Natl.Acad.Sci.USA, 96, 1999
3C59
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BU of 3c59 by Molmil
Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain
分子名称: Exendin-4, Glucagon-like peptide 1 receptor, decyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside
著者Runge, S.
登録日2008-01-31
公開日2008-02-19
最終更新日2018-05-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the Ligand-bound Glucagon-like Peptide-1 Receptor Extracellular Domain
J.Biol.Chem., 283, 2008
174L
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BU of 174l by Molmil
PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
分子名称: SULFATE ION, T4 LYSOZYME
著者Zhang, X.-J, Matthews, B.W.
登録日1995-03-24
公開日1995-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
1JTN
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BU of 1jtn by Molmil
Alternative Structures of a Sequence Extended T4 Lysozyme Show that the Highly Conserved Beta-Sheet Region has weak intrinsic Folding Propensity
分子名称: LYSOZYME, SULFATE ION
著者Sagermann, M, Matthews, B.W.
登録日2001-08-21
公開日2002-03-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of a T4-lysozyme Duplication-extension Mutant Demonstrate that the Highly Conserved beta-Sheet Region has Low Intrinsic Folding Propensity
J.Mol.Biol., 316, 2002
6ZG4
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BU of 6zg4 by Molmil
Structure of M1-StaR-T4L in complex with HTL0009936 at 2.35A
分子名称: Muscarinic acetylcholine receptor M1,Endolysin,Muscarinic acetylcholine receptor M1, OLEIC ACID, PHOSPHATE ION, ...
著者Rucktooa, P, Cooke, R.M.
登録日2020-06-18
公開日2021-10-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Cell, 184, 2021
4PHU
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BU of 4phu by Molmil
Crystal structure of Human GPR40 bound to allosteric agonist TAK-875
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DIMETHYL SULFOXIDE, Free fatty acid receptor 1,Lysozyme, ...
著者Srivastava, A, Yano, J.K, Hirozane, Y, Kefala, G, Snell, G, Lane, W, Gruswitz, F, Ivetac, A, Aertgeerts, K, Nguyen, J, Jennings, A, Okada, K.
登録日2014-05-07
公開日2014-07-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.332 Å)
主引用文献High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875.
Nature, 513, 2014
4YXA
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BU of 4yxa by Molmil
Complex of SpaO(SPOA1,2 SeMet) and OrgB(APAR)::T4lysozyme fusion protein
分子名称: Oxygen-regulated invasion protein OrgB,Endolysin, Surface presentation of antigens protein SpaO
著者Notti, R.Q, Stebbins, C.E.
登録日2015-03-22
公開日2015-06-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
2HUM
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BU of 2hum by Molmil
Crystal structure of T4 Lysozyme D72C synthetic dimer
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Lysozyme
著者Banatao, D.R, Cascio, D, Yeates, T.O.
登録日2006-07-26
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献An approach to crystallizing proteins by synthetic symmetrization.
Proc.Natl.Acad.Sci.Usa, 103, 2006
8A5X
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BU of 8a5x by Molmil
Crystal structure of phosphatidyl inositol 4-kinase II beta in complex with MM1373
分子名称: 4-azanyl-7-[3-(hydroxymethyl)phenyl]quinazoline-6-carboxamide, Phosphatidylinositol 4-kinase type 2-beta,Endolysin
著者Klima, M, Boura, E.
登録日2022-06-16
公開日2022-10-05
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold.
Bioorg.Med.Chem.Lett., 76, 2022
2RH1
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BU of 2rh1 by Molmil
High resolution crystal structure of human B2-adrenergic G protein-coupled receptor.
分子名称: (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1,4-BUTANEDIOL, ACETAMIDE, ...
著者Cherezov, V, Rosenbaum, D.M, Hanson, M.A, Rasmussen, S.G.F, Thian, F.S, Kobilka, T.S, Choi, H.J, Kuhn, P, Weis, W.I, Kobilka, B.K, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2007-10-05
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.
Science, 318, 2007
2B70
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T4 Lysozyme mutant L99A at ambient pressure
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme
著者Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M, TB Structural Genomics Consortium (TBSGC)
登録日2005-10-03
公開日2005-11-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation
Proc.Natl.Acad.Sci.Usa, 102, 2005
2B6Z
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T4 Lysozyme mutant L99A at ambient pressure
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme
著者Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M.
登録日2005-10-03
公開日2005-11-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation
Proc.Natl.Acad.Sci.Usa, 102, 2005
2B6Y
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T4 Lysozyme mutant L99A at ambient pressure
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme
著者Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M.
登録日2005-10-03
公開日2005-11-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation
Proc.Natl.Acad.Sci.Usa, 102, 2005
1SSY
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Crystal structure of phage T4 lysozyme mutant G28A/I29A/G30A/C54T/C97A
分子名称: Lysozyme
著者He, M.M, Baase, W.A, Xiao, H, Heinz, D.W, Matthews, B.W.
登録日2004-03-24
公開日2004-10-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation
Protein Sci., 13, 2004

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