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PDB: 12 件
2QND
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Crystal Structure of the KH1-KH2 domains from human Fragile X Mental Retardation Protein
分子名称: FMR1 protein, MAGNESIUM ION
著者Valverde, R, Regan, L.
登録日2007-07-18
公開日2007-11-06
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Fragile X mental retardation syndrome: structure of the KH1-KH2 domains of fragile X mental retardation protein.
Structure, 15, 2007
5UWO
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Crystal Structure of Engineered FMRP-1b NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Engineered FMRP-1b peptide, Exportin-1, GLYCEROL, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.347 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
5UWJ
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Crystal Structure of FMRP NES Peptide in complex with CRM1-Ran-RanBP1
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Fung, H.Y.J, Chook, Y.M.
登録日2017-02-21
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.221 Å)
主引用文献Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals.
Elife, 6, 2017
2FMR
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KH1 FROM THE FRAGILE X PROTEIN FMR1, NMR, 18 STRUCTURES
分子名称: FMR1 PROTEIN
著者Musco, G, Kharrat, A, Stier, G, Fraternali, F, Gibson, T.J, Nilges, M, Pastore, A.
登録日1997-10-06
公開日1998-04-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The solution structure of the first KH domain of FMR1, the protein responsible for the fragile X syndrome.
Nat.Struct.Biol., 4, 1997
2BKD
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Structure of the N-terminal domain of Fragile X Mental Retardation Protein
分子名称: Fragile X messenger ribonucleoprotein 1
著者Ramos, A, Hollingworth, D, Adinolfi, S, Castets, M, Kelly, G, Frenkiel, T.A, Bardoni, B, Pastore, A.
登録日2005-02-15
公開日2006-01-18
最終更新日2023-02-01
実験手法SOLUTION NMR
主引用文献The structure of the N-terminal domain of the fragile X mental retardation protein: a platform for protein-protein interaction.
Structure, 14, 2006
2LA5
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RNA Duplex-Quadruplex Junction Complex with FMRP RGG peptide
分子名称: Fragile X mental retardation 1 protein, RNA (36-MER)
著者Phan, A, Kuryavyi, V, Darnell, J, Serganov, A, Majumdar, A, Ilin, S, Darnell, R, Patel, D.
登録日2011-03-03
公開日2011-06-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction.
Nat.Struct.Mol.Biol., 18, 2011
5DE8
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Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, iridium hexammine bound form.
分子名称: Fragile X mental retardation protein 1, IRIDIUM HEXAMMINE ION, POTASSIUM ION, ...
著者Vasilyev, N, Polonskaia, A, Darnell, J.C, Darnell, R.B, Patel, D.J, Serganov, A.
登録日2015-08-25
公開日2015-09-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.1003 Å)
主引用文献Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP.
Proc.Natl.Acad.Sci.USA, 112, 2015
5DEA
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Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA, cesium bound form.
分子名称: CESIUM ION, Fragile X mental retardation protein 1, POTASSIUM ION, ...
著者Vasilyev, N, Polonskaia, A, Darnell, J.C, Darnell, R.B, Patel, D.J, Serganov, A.
登録日2015-08-25
公開日2015-09-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.7973 Å)
主引用文献Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP.
Proc.Natl.Acad.Sci.USA, 112, 2015
4OVA
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Structure of the two tandem Tudor domains and a new identified KH0 domain from human Fragile X Mental Retardation Protein
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Fragile X mental retardation protein 1
著者Chen, Z.H, Chen, Z.Z.
登録日2014-02-21
公開日2015-02-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The amino-terminal structure of human fragile X mental retardation protein obtained using precipitant-immobilized imprinted polymers
Nat Commun, 6, 2015
5DE5
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Crystal structure of the complex between human FMRP RGG motif and G-quadruplex RNA.
分子名称: Fragile X mental retardation protein 1, POTASSIUM ION, sc1
著者Vasilyev, N, Polonskaia, A, Darnell, J.C, Darnell, R.B, Patel, D.J, Serganov, A.
登録日2015-08-25
公開日2015-09-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.0011 Å)
主引用文献Crystal structure reveals specific recognition of a G-quadruplex RNA by a beta-turn in the RGG motif of FMRP.
Proc.Natl.Acad.Sci.USA, 112, 2015
4QW2
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FMRP N-terminal domain (R138Q)
分子名称: 1,2-ETHANEDIOL, Fragile X mental retardation protein 1, LEAD (II) ION
著者Myrick, L.K, Hashimoto, H, Cheng, X, Warren, S.T.
登録日2014-07-16
公開日2014-12-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.989 Å)
主引用文献Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain.
Hum.Mol.Genet., 24, 2015
4QVZ
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FMRP N-terminal domain
分子名称: 1,2-ETHANEDIOL, Fragile X mental retardation protein 1
著者Myrick, L.K, Hashimoto, H, Cheng, X, Warren, S.T.
登録日2014-07-16
公開日2014-12-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.195 Å)
主引用文献Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain.
Hum.Mol.Genet., 24, 2015

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