Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 24 件
6TZ3
DownloadVisualize
BU of 6tz3 by Molmil
Crystal Structure of Human Synaptotagmin 1 C2B without Ca2+
分子名称: SULFATE ION, Synaptotagmin-1
著者Dominguez, M.J, Karmakar, S, Meyer, A.G, Sutton, R.B.
登録日2019-08-09
公開日2020-05-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
6U4U
DownloadVisualize
BU of 6u4u by Molmil
1.3 A structure of a pathogenic human Syt 1 C2B (I368T)
分子名称: SULFATE ION, Synaptotagmin-1
著者Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B.
登録日2019-08-26
公開日2020-05-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
7TUA
DownloadVisualize
BU of 7tua by Molmil
Human Synaptotagmin-1 C2B Y312F without Ca2+
分子名称: SULFATE ION, Synaptotagmin
著者Dominguez, M.J, Karmakar, S, Fuson, K.L, Sutton, R.B.
登録日2022-02-02
公開日2023-03-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Human Synaptotagmin-1 C2B Y312F without Ca2+
To Be Published
3F04
DownloadVisualize
BU of 3f04 by Molmil
Crystal Structure of Synaptotagmin I C2A domain
分子名称: SULFATE ION, Synaptotagmin-1
著者Guo, F, Dakshinamurthy, R, Thallapuranam, S.K.K, Sakon, J.
登録日2008-10-24
公開日2009-09-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Cystal structure of synaptotagmin I C2A
to be published
3F00
DownloadVisualize
BU of 3f00 by Molmil
Crystal Structure of Synaptotagmin I C2A domain with Cu(II)
分子名称: COPPER (II) ION, SULFATE ION, Synaptotagmin-1
著者Guo, F, Dakshinamurthy, R, Thallapuranam, S.K.K, Sakon, J.
登録日2008-10-24
公開日2009-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Crystal structure of Synaptotagmin I C2A
To be Published
6U4W
DownloadVisualize
BU of 6u4w by Molmil
1.4 A structure of a pathogenic human Syt 1 C2B (D366E)
分子名称: SULFATE ION, Synaptotagmin-1
著者Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B.
登録日2019-08-26
公開日2020-05-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
3F05
DownloadVisualize
BU of 3f05 by Molmil
Crystal Structure of Synaptotagmin I C2A domain with Mn(II)
分子名称: MANGANESE (II) ION, SULFATE ION, Synaptotagmin-1
著者Guo, F, Dakshinamurthy, R, Thallapuranam, S.K.K, Sakon, J.
登録日2008-10-24
公開日2009-10-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Cystal structure of synaptotagmin I C2A
to be published
7U4Q
DownloadVisualize
BU of 7u4q by Molmil
Human Synaptotagmin-1 C2A Y181F Ca2+ bound
分子名称: CALCIUM ION, Synaptotagmin-1
著者Dominguez, M.J, Karmakar, S, Fuson, K.L, Sutton, R.B.
登録日2022-02-28
公開日2023-03-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Human Synaptotagmin-1 C2A Y181F Ca2+ bound
To Be Published
6U41
DownloadVisualize
BU of 6u41 by Molmil
1.7 angstrom structure of a pathogenic human Syt 1 C2B (D304G)
分子名称: SULFATE ION, Synaptotagmin-1
著者Dominguez, M.J, Bradberry, M.M, Chapman, E.R, Sutton, R.B.
登録日2019-08-22
公開日2020-05-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder.
Neuron, 107, 2020
3F01
DownloadVisualize
BU of 3f01 by Molmil
Crystal Structure of Synaptotagmin I C2A domain with Cu(II)
分子名称: COPPER (II) ION, SULFATE ION, Synaptotagmin-1
著者Guo, F, Dakshinamurthy, R, Thallapuranam, S.K.K, Sakon, J.
登録日2008-10-24
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of synaptotagmin I C2A
To be Published
4V11
DownloadVisualize
BU of 4v11 by Molmil
Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84
分子名称: CALCIUM ION, GLYCEROL, SYNAPTIC VESICLE GLYCOPROTEIN 2A, ...
著者Zhang, N, Gordon, S.L, Fritsch, M.J, Esoof, N, Campbell, D, Gourlay, R, Velupillai, S, Macartney, T, Peggie, M, vanAalten, D.M.F, Cousin, M.A, Alessi, D.R.
登録日2014-09-22
公開日2015-02-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1.
J.Neurosci., 35, 2015
6G5K
DownloadVisualize
BU of 6g5k by Molmil
Crystal structure of the binding domain of Botulinum Neurotoxin type B in complex with human synaptotagmin 1
分子名称: Botulinum neurotoxin type B, Synaptotagmin-1
著者Masuyer, G, Elliot, M, Favre-Guilmard, C, Liu, S.M, Maignel, J, Beard, M, Carre, D, Kalinichev, M, Lezmi, S, Mir, I, Nicoleau, C, Palan, S, Perier, C, Raban, E, Dong, M, Krupp, J, Stenmark, P.
登録日2018-03-29
公開日2019-01-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models.
Sci Adv, 5, 2019
6QNS
DownloadVisualize
BU of 6qns by Molmil
Crystal structure of the binding domain of Botulinum Neurotoxin type B mutant I1248W/V1249W in complex with human synaptotagmin 1 and GD1a receptors
分子名称: Botulinum neurotoxin type B, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Synaptotagmin-1
著者Masuyer, G, Yin, L, Zhang, S, Miyashita, S.I, Dong, M, Stenmark, P.
登録日2019-02-12
公開日2020-02-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy.
Plos Biol., 18, 2020
6ZVN
DownloadVisualize
BU of 6zvn by Molmil
Botulinum neurotoxin B2 binding domain in complex with human synaptotagmin I
分子名称: Neurotoxin, Synaptotagmin-1
著者Davies, J.R, Masuyer, G, Stenmark, P.
登録日2020-07-25
公開日2020-10-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and Biochemical Characterization of Botulinum Neurotoxin Subtype B2 Binding to Its Receptors.
Toxins, 12, 2020
6G5F
DownloadVisualize
BU of 6g5f by Molmil
Crystal structure of an engineered Botulinum Neurotoxin type B mutant E1191M/S1199Y in complex with human synaptotagmin 1
分子名称: Botulinum neurotoxin type B, GLYCEROL, MALONATE ION, ...
著者Masuyer, G, Elliot, M, Favre-Guilmard, C, Liu, S.M, Maignel, J, Beard, M, Carre, D, Kalinichev, M, Lezmi, S, Mir, I, Nicoleau, C, Palan, S, Perier, C, Raban, E, Dong, M, Krupp, J, Stenmark, P.
登録日2018-03-29
公開日2019-01-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models.
Sci Adv, 5, 2019
4ISQ
DownloadVisualize
BU of 4isq by Molmil
Binding domain of Botulinum neurotoxin DC in complex with human synaptotagmin I
分子名称: GLYCEROL, Neurotoxin, SULFATE ION, ...
著者Berntsson, R.P.-A, Peng, L, Svensson, L.M, Dong, M, Stenmark, P.
登録日2013-01-17
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II.
Structure, 21, 2013
2R83
DownloadVisualize
BU of 2r83 by Molmil
Crystal structure analysis of human synaptotagmin 1 C2A-C2B
分子名称: CHLORIDE ION, Synaptotagmin-1
著者Sutton, R.B, Fuson, K.L, Montes, M, Robert, J.J.
登録日2007-09-10
公開日2008-02-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of human synaptotagmin 1 C2AB in the absence of Ca2+ reveals a novel domain association.
Biochemistry, 46, 2007
8B8I
DownloadVisualize
BU of 8b8i by Molmil
Nanobody (NbLumSyt1) bound to human Syt1
分子名称: Nanobody (NbLumSyt1), Synaptotagmin-1
著者Liu, H, Scaletti, E, Stenmark, P.
登録日2022-10-04
公開日2024-04-17
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Nanobody (NbLumSyt1) bound to human Syt1
To Be Published
2LHA
DownloadVisualize
BU of 2lha by Molmil
Solution structure of C2B with IP6
分子名称: INOSITOL HEXAKISPHOSPHATE, Synaptotagmin-1
著者Joung, M, Mohan, S.K, Yu, C.
登録日2011-08-08
公開日2012-05-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Molecular Level Interaction of Inositol Hexaphosphate with the C2B Domain of Human Synaptotagmin I
Biochemistry, 2012
2K4A
DownloadVisualize
BU of 2k4a by Molmil
FGF-1-C2A binary complex structure: a key component in the fibroblast growthfactor non-classical pathway
分子名称: Heparin-binding growth factor 1, Synaptotagmin-1
著者Yu, C, Mohan, S.K.
登録日2008-06-02
公開日2009-06-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献FGF-1-C2A binary complex structure: key component in the acidic fibroblast growth factor release
To be Published
2K45
DownloadVisualize
BU of 2k45 by Molmil
C2A domain of synaptototagmin I solution structure in the FGF-1-C2A binary complex: key component in the fibroblast growthfactor non-classical pathway
分子名称: Synaptotagmin-1
著者Mohan, S.K, Yu, C.
登録日2008-05-28
公開日2009-06-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献FGF-1-C2A binary complex structure: key component in the acidic fibroblast growth factor release
To be Published
2N1T
DownloadVisualize
BU of 2n1t by Molmil
Dynamic binding mode of a synaptotagmin-1-SNARE complex in solution
分子名称: Synaptosomal-associated protein 25, Synaptotagmin-1, Syntaxin-1A, ...
著者Brewer, K, Bacaj, T, Cavalli, A, Camilloni, C, Swarbrick, J, Liu, J, Zhou, A, Zhou, P, Barlow, N, Xu, J, Seven, A, Prinslow, E, Voleti, R, Haussinger, D, Bonvin, A, Tomchick, D, Vendruscolo, M, Graham, B, Sudhof, T, Rizo, J.
登録日2015-04-21
公開日2015-06-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution.
Nat.Struct.Mol.Biol., 22, 2015
2KI6
DownloadVisualize
BU of 2ki6 by Molmil
The FGF1-S100A13-C2A hetero-hexameric complex structure: A component in the non-classical pathway for FGF1 secretion
分子名称: Heparin-binding growth factor 1, Protein S100-A13, Synaptotagmin-1
著者Krishna, S.M, Rani, S.G, Yu, C.
登録日2009-04-28
公開日2010-03-09
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献The heterohexameric complex structure, a component in the non-classical pathway for fibroblast growth factor 1 (FGF1) secretion.
J.Biol.Chem., 285, 2010
2K8M
DownloadVisualize
BU of 2k8m by Molmil
S100A13-C2A binary complex structure
分子名称: Protein S100-A13, Putative uncharacterized protein
著者Mohan, S.K, Rani, S.G, Kumar, S.M, Yu, C.
登録日2008-09-14
公開日2009-03-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献S100A13-C2A binary complex structure-a key component in the acidic fibroblast growth factor for the non-classical pathway.
Biochem.Biophys.Res.Commun., 380, 2009

222036

件を2024-07-03に公開中

PDB statisticsPDBj update infoContact PDBjnumon